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Sub-mucosal agent delivery, apparatus, system and method

  • US 8,652,118 B2
  • Filed: 02/10/2011
  • Issued: 02/18/2014
  • Est. Priority Date: 04/08/2010
  • Status: Active Grant
First Claim
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1. A method for administering a pharmacological agent formulation to a sub-mucosal compartment of an organ, comprising the steps of (i) providing a needleless agent delivery apparatus containing the pharmacological agent formulation in an internal formulation chamber, said agent delivery apparatus including an elongated agent delivery member, said agent delivery member including an integral nozzle member-positioning hood assembly, said nozzle member-positioning hood assembly comprising a first nozzle member and a deformable positioning hood that is adapted to substantially conform to the surface of an organ and position said agent delivery member on said organ when in an engagement position thereon, and force generating means that is adapted to generate sufficient force to expel the pharmacological agent formulation from said agent delivery apparatus and into an organ, (ii) positioning said agent delivery apparatus on a surface of a first organ, and (iii) activating the agent delivery apparatus, whereby the pharmacological agent formulation is expelled from the agent delivery apparatus by said force generating means and delivered to the surface of said first organ with a delivery pressure in the range of approximately 100-1000 psi and, whereby a first volume of the pharmacological agent formulation is administered to a sub-mucosal compartment of said first organ.

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