System and method for conditioning implantable medical devices
First Claim
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1. A system for passivating a biomaterial surface, said system comprising:
- (a) a treatment chamber housing defining a chamber therewithin, and having a treatment fluid inlet and a treatment fluid outlet in fluid communication with said chamber;
(b) a treatment fluid source comprising blood or blood plasma;
(c) a first treatment fluid conduit for conveying treatment fluid from said source to said treatment chamber;
(d) a first electrode electrically coupled to said biomaterial surface in said chamber, said first electrode providing an electrical conduction path from said housing to said chamber; and
(e) an electrical energy source for generating therapeutic electrical current, said electrical energy source being capable of delivering said therapeutic electrical current to said first electrode.
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Abstract
A method for passivating a biomaterial surface includes exposing the biomaterial surface to therapeutic electrical energy in the presence of blood or plasma. The biomaterial surface may be removably secured within a chamber of a treatment system, which communicates the therapeutic electrical energy to the biomaterial surface while interfacing the biomaterial surface with blood or plasma.
67 Citations
17 Claims
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1. A system for passivating a biomaterial surface, said system comprising:
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(a) a treatment chamber housing defining a chamber therewithin, and having a treatment fluid inlet and a treatment fluid outlet in fluid communication with said chamber; (b) a treatment fluid source comprising blood or blood plasma; (c) a first treatment fluid conduit for conveying treatment fluid from said source to said treatment chamber; (d) a first electrode electrically coupled to said biomaterial surface in said chamber, said first electrode providing an electrical conduction path from said housing to said chamber; and (e) an electrical energy source for generating therapeutic electrical current, said electrical energy source being capable of delivering said therapeutic electrical current to said first electrode. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A system for passivating a biomaterial surface, said system comprising:
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(a) a treatment chamber housing defining a chamber therewithin, and having treatment fluid inlet and a treatment fluid outlet in fluid communication with said chamber; (b) a treatment fluid source; (c) a first treatment fluid conduit for conveying treatment fluid from said source to said treatment chamber; (d) a first electrode electrically coupled to said biomaterial surface in said chamber, said first electrode providing an electrical conduction path from said housing to said chamber; (e) a second treatment fluid conduit for conveying treatment fluid from said treatment chamber to a cardiopulmonary bypass system; and (f) an electrical energy source for generating therapeutic electrical current, said electrical enemy source being capable of delivering said therapeutic electrical current to said first electrode. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17)
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Specification