Electrophysiological analysis system
DCFirst Claim
1. An electrophysiological analysis system which is intended, in particular for the detection of pathological conditions, the system comprising:
- a series of electrodes intended to be placed at various regions of a human body distant from one another;
an adjustable DC voltage source controlled in order to produce successive waves of a DC voltage which varies from one wave to the other, a duration of the waves being greater than or equal to approximately 0.2 second;
a switching circuit designed to selectively connect a pair of active electrodes to the voltage source, and to connect at least one other high-impedance electrode;
a measuring circuit designed to collect data representative of current in the active electrodes and of the potentials on at least some electrodes connected in high impedance, in response to the application of the waves, and in that, from one wave to the other, the range of voltages covered by the waves is capable of causing the appearance or disappearance of electrochemical phenomena in a vicinity of the active electrodes; and
the measuring circuit including a resistor designed to be connected between one of the electrodes of an active pair and a reference voltage.
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Abstract
The invention provides an electrophysiological analysis system, in particular for detecting pathological states. This system comprises: electrodes intended to be placed in different regions of the body that are well away from each other; an adjustable DC voltage source for generating successive DC voltage pulses varying in magnitude from one pulse to another, the duration of the pulses being equal to or greater than about 0.2 seconds; a switching circuit for selectively connecting a pair of active electrodes to the voltage source and for connecting at least one other high-impedance electrode; and a measurement circuit for recording data representative of the current in the active electrodes and potentials on at least certain high-impedance connected electrodes in response to the application of said pulses. The range of voltages covered causes, from one pulse to another, the appearance or disappearance of electrochemical phenomena in the vicinity of the active electrodes.
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Citations
23 Claims
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1. An electrophysiological analysis system which is intended, in particular for the detection of pathological conditions, the system comprising:
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a series of electrodes intended to be placed at various regions of a human body distant from one another; an adjustable DC voltage source controlled in order to produce successive waves of a DC voltage which varies from one wave to the other, a duration of the waves being greater than or equal to approximately 0.2 second; a switching circuit designed to selectively connect a pair of active electrodes to the voltage source, and to connect at least one other high-impedance electrode; a measuring circuit designed to collect data representative of current in the active electrodes and of the potentials on at least some electrodes connected in high impedance, in response to the application of the waves, and in that, from one wave to the other, the range of voltages covered by the waves is capable of causing the appearance or disappearance of electrochemical phenomena in a vicinity of the active electrodes; and the measuring circuit including a resistor designed to be connected between one of the electrodes of an active pair and a reference voltage. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A method for diagnosing a patient, with a view to detecting a disease, a pathological predisposition or another disorder, wherein the method comprises:
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receiving a set of data comprising measurements revealing electrochemical phenomena in the vicinity of the electrodes applied to skin of the patient at predetermined locations; accessing at least one set of stored reference data comprising measurements revealing electrochemical phenomena, which were obtained under the same conditions, on patients identified as suffering or not suffering from this disease; and reconciling the set of data received with the sets of reference data, and, based on proximity criteria between the set of data received and the sets of reference data, identifying the patient as ill or not ill; wherein the measured data is obtained from current values in the active electrodes and from potential values on high-impedance electrodes, in response to the application of voltage waves between active electrodes, the level of which varies from one wave to the other, in order to cause the appearance or disappearance of electrochemical phenomena in the vicinity of the active electrodes. - View Dependent Claims (20, 21, 22, 23)
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Specification