System and method for increasing relative intensity between cathodes and anodes of neurostimulation system

• US 8,660,655 B2
• Filed: 07/08/2013
• Issued: 02/25/2014
• Est. Priority Date: 07/28/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Peterson, David K. L., Bradley, Kerry, Holsheimer, Jan
• Primary Examiner(s): Wieland, Robert N
• Application Number:
  US13/937,035
• Publication Number:
  US 20130296992A1
• Time in Patent Office: 232 Days
• Field of Search: 607/46
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/3616 Voltage density or current density

Abstract

A method and neurostimulation system for providing therapy to a patient is provided. A plurality of electrodes is placed adjacent to tissue of the patient. The electrodes include first and second electrodes, with the first electrode having a first tissue contacting surface area and the second electrode having a second tissue contact surface area greater than the first tissue contacting surface area. Anodic electrical current is simultaneously sourced from one of the first and second electrodes to the tissue and while cathodic electrical current is sunk from the tissue to another of the first and second electrodes to provide the therapy to the patient.

Claims

1. A method of providing therapy to a patient, comprising:

placing a plurality of electrodes adjacent to tissue of the patient, the electrodes including first and second electrodes, the first electrode having a first tissue contacting surface area and the second electrode having a second tissue contacting surface area greater than the first tissue contacting surface area; and

simultaneously sourcing anodic electrical current from the first electrode to a first neural fiber bundle, thereby increasing an action potential threshold of the first neural fiber bundle, and sinking cathodic electrical current from a second neural fiber bundle to the second electrode, thereby providing the therapy to the patient.

2. The method of claim 1, wherein electrical current is conveyed between the first and second electrodes to source the anodic electrical current from the first electrode and sink the cathodic electrical current to the second electrode.

3. The method of claim 1, wherein the second tissue contacting surface area is at least twice the first tissue contacting surface area.

4. The method of claim 1, wherein the current density on the first tissue contacting surface is greater than the current density on the second tissue contacting surface.

5. The method of claim 1, wherein the anodic electrical current and cathodic electrical current comprises a plurality of electrical pulses.

6. The method of claim 1, wherein the tissue is spinal cord tissue.

7. The method of claim 6, wherein the electrodes are arranged medio-laterally along the spinal cord tissue.

8. The method of claim 7, wherein the second neural fiber bundle comprises dorsal column neural fibers of the spinal cord tissue, the first neural fiber bundle comprises dorsal root neural fibers of the spinal cord tissue, the sunk cathodic electrical current generates action potentials in the dorsal column neural fibers to provide the therapy to the patient, and the sourced anodic electrical current increases the action potential threshold of the at least one dorsal root neural fiber.

9. The method of claim 6, wherein the electrodes are arranged rostro-caudally along the spinal cord tissue.

10. The method of claim 9, wherein each of the first and second neural fiber bundles comprises dorsal column neural fibers of the spinal cord tissue, the second electrode is a first distance from the first neural fiber bundle and is a second greater distance from the second neural fiber bundle, the sunk cathodic electrical current generates action potentials in the first neural fiber bundle, and generates additional action potentials in the second neural fiber bundle to provide therapy to the patient, and the sourced anodic electrical current blocks at least some of the action potentials in the first neural fiber bundle.

11. A neurostimulation system, comprising:

a lead;

a plurality of electrodes carried by the lead, the plurality of electrodes configured for being placed adjacent to tissue of a patient, the electrodes including first and second electrodes, the first electrode having a first tissue contacting surface area and the second electrode having a second tissue contact surface area greater than the first tissue contacting surface area; and

output stimulation circuitry coupled to the plurality of electrodes, the output stimulation circuitry configured for sourcing anodic electrical current to the first electrode and sinking cathodic electrical current from the second electrode to provide therapy to the patient.

12. The neurostimulation system of claim 11, wherein the output stimulation circuitry is configured for conveying electrical current between the first and second electrodes to source the anodic electrical current from the first electrode and sink the cathodic electrical current to the second electrode.

13. The neurostimulation system of claim 11, wherein the second tissue contacting surface area is at least twice the first tissue contacting surface area.

14. The neurostimulation system of claim 11, wherein the output stimulation circuitry is configured for generating a current density on the first tissue contacting surface that is greater than the current density on the second tissue contacting surface.

15. The neurostimulation system of claim 11, wherein the anodic electrical current and cathodic electrical current comprises a plurality of electrical pulses.

16. The neurostimulation system of claim 11, wherein the lead is a spinal cord stimulation lead.

17. The neurostimulation system of claim 11, wherein the lead is an in-line lead, and the electrodes are arranged in a single column along the axis of the in-line lead.

18. The neurostimulation system of claim 11, wherein the lead is a paddle lead, and the electrodes comprises three electrodes arranged along a line transverse to the axis of the paddle lead.