Extracorporeal fluid circuit and related components

• US 8,663,463 B2
• Filed: 02/18/2009
• Issued: 03/04/2014
• Est. Priority Date: 02/18/2009
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Inventors: Weaver, Colin, Crnkovich, Martin Joseph, Kotsos, Michael Emmanuel, Frazer, John Marion
• Primary Examiner(s): Kim, Vickie
• Assistant Examiner(s): FITZSIMMONS, ALLISON G
• Application Number:
  US12/388,003
• Publication Number:
  US 20100206784A1
• Time in Patent Office: 1,840 Days
• Field of Search: None
• US Class Current: 210/94
• CPC Class Codes: A61M 1/3639 Blood pressure control, pressure transducers specially adapted therefor
• CPC Class Codes: A61M 2205/7536 allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
• CPC Class Codes: B01D 11/00 Solvent extraction

Abstract

A vent assembly is described for use in an extracorporeal fluid unit. A vent structure adjacent to a micro-porous membrane forms the assembly. The vent structure is porous and changes color when the vent structure becomes wet, thereby providing a visual indication that the vent structure has been exposed to liquid.

Claims

1. An extracorporeal medical fluid circuit component, comprising:

a vent assembly comprising;

a micro-porous membrane; and

a vent structure adjacent to the micro-porous membrane, the vent structure comprising a porous material capable of changing color when the porous material is moistened, the porous material also being capable of swelling in a manner to create a seal that prevents the passage of liquid through the porous material when the porous material is moistened,

wherein the component is capable of being used in an extracorporeal medical fluid circuit.

2. The component of claim 1, wherein the vent structure comprises a color change additive.

3. The component of claim 2, wherein the color change additive comprises powdered or granulated dye or a pH indicator.

4. The component of claim 2, wherein the color change additive comprises bromophenol blue.

5. The component of claim 1, wherein the vent structure comprises about 0.05% by weight to about 2% by weight of a color change additive.

6. The component of claim 1, wherein the vent structure includes polyethylene, polypropylene, or polystyrene.

7. The component of claim 1, wherein the vent structure comprises carboxymethylcellulose.

8. The component of claim 1, wherein the vent structure comprises a blend of polyethylene, carboxymethylcellulose, and a color change additive.

9. The component of claim 7, wherein a color change additive is covalently bonded to the carboxymethylcellulose.

10. The component of claim 1, wherein the vent structure comprises a blend of polyethylene, carboxymethylcellulose, and a pH indicator.

11. The component of claim 10, wherein the pH indicator is bromophenol blue.

12. The component of claim 7, wherein a pH indicator is covalently bonded to the carboxymethylcellulose.

13. The component of claim 1, wherein the vent structure has an average pore size of about 15 microns to about 45 microns.

14. The component of claim 1, wherein the vent structure has an average pore size of about 0.05 to about 0.45 microns.

15. The component of claim 1, wherein the micro-porous membrane has an average pore size of about 0.2 microns.

16. The component of claim 1, wherein the component is configured for use with a device adapted to remove air from blood.

17. The component of claim 1, wherein the component is capable of being used in a blood circuit.

18. The component of claim 1, wherein the micro-porous membrane is hydrophobic.

32. The component of claim 1, wherein the porous material of the vent structure is configured to allow gases to pass therethrough prior to being moistened.

34. The component of claim 1, wherein the component is configured for use in a transducer protector.

19. A system, comprising:

a machine body;

a pump on the machine body;

fluid circuitry in fluid communication with the pump, wherein the pump is configured to push fluid through the circuitry;

a vent assembly in fluid communication with the fluid circuitry, the vent assembly comprising;

a micro-porous membrane; and

a vent structure adjacent to the micro-porous membrane, the vent structure comprising a porous material capable of changing color when the porous material is moistened, the porous material also being capable of swelling in a manner to create a seal that prevents the passage of liquid through the porous material when the porous material is moistened.

20. The system of claim 19, wherein the system is a dialysis system.

21. The system of claim 20, wherein the dialysis system is a hemodialysis system.

22. The system of claim 19, further comprising an electro-optical assembly arranged to detect a change in color of the vent structure.

23. The system of claim 22, wherein the electro-optical assembly comprises

a light emitter arranged to emit light towards the vent structure;

and

a light detector arranged to detect light reflected off of the vent structure.

24. The system of claim 23, further comprising a controller in electrical communication with the electro-optical assembly and the pump, wherein the controller is configured to halt operation of the pump in response to receiving a signal from the electro-optical assembly indicating that the vent structure has changed color.

25. The system of claim 23, further comprising a speaker;

and a controller in electrical communication with the electro-optical assembly and the speaker,

wherein the controller is configured to sound an audible alarm through the speaker in response to receiving a signal from the electro-optical assembly indicating that the vent structure has changed color.

26. The system of claim 25, wherein the controller is configured to sound an alarm in response to receiving a signal from the electro-optical assembly indicating that the light detector detected reflected light having a wavelength that falls within a predetermined range.

27. The system of claim 26, wherein the predetermined range is 440 nm to about 490 nm.

28. The system of claim 23, further comprising a display;

and a controller in electrical communication with the electro-optical assembly and the display,

wherein the controller is configured to provide a visual alarm on the display in response to receiving a signal from the electro-optical assembly indicating that the vent structure has changed color.

29. The system of claim 19, further comprising:

a pressure transducer; and

a transducer protector disposed between, and in fluid communication with, the fluid circuitry and the pressure transducer,

wherein the transducer protector comprises the vent assembly.

30. The system of claim 19, further comprising:

a chamber in fluid communication with the fluid circuitry, the chamber comprising

a fluid entry port; and

a fluid exit port,

wherein the fluid circuitry is configured to allow liquid to pass through the chamber from the entry port to the exit port, and

wherein the vent assembly is arranged to allow gas to exit the chamber through the vent assembly as the liquid passes through the chamber.

31. The system of claim 19, wherein the micro-porous filter is hydrophobic.

33. The system of claim 19, wherein the porous material of the vent structure is configured to allow gases to pass therethrough prior to being moistened.

35. A transducer protector comprising:

a body defining a fluid pathway; and

a vent assembly disposed within the fluid pathway, the vent assembly comprising

a micro-porous membrane; and

a vent structure adjacent to the micro-porous membrane, the vent structure comprising a porous material capable of changing color when the porous material is moistened, the porous material also being capable of swelling in a manner to create a seal that prevents the passage of liquid through the porous material when the porous material is moistened,

wherein the transducer protector is capable of being connected in fluid communication with a fluid circuit and a pressure transducer such that the vent assembly inhibits liquid flowing within the fluid circuit from contacting the pressure transducer.

36. The transducer protector of claim 35, wherein the porous material is capable of swelling when moistened.

37. The transducer protector of claim 35, wherein the micro-porous membrane is hydrophobic.

38. An extracorporeal medical fluid circuit apparatus, comprising:

a chamber including a fluid entry port and a fluid exit port; and

a vent assembly comprising;

a micro-porous membrane; and

a vent structure adjacent to the micro-porous membrane, the vent structure comprising a porous material capable of changing color when the porous material is moistened, the porous material also being capable of swelling in a manner to create a seal that prevents the passage of liquid through the porous material when the porous material is moistened,

wherein the fluid entry port and the fluid exit port are arranged to allow liquid to pass through the chamber from the fluid entry port to the fluid exit port, and

wherein the vent assembly is arranged to allow gas to exit the chamber as the liquid passes through the chamber.

39. The apparatus of claim 38, wherein the porous material includes an additive that is capable of swelling when moistened.

40. The apparatus of claim 38, wherein the micro-porous membrane is hydrophobic.