Fluid transfer device

• US 8,667,996 B2
• Filed: 05/04/2010
• Issued: 03/11/2014
• Est. Priority Date: 05/04/2009
• Status: Active Grant

• Current Assignee: Mannkind Corporation
• Original Assignee: Valeritas, Inc. (Zealand Pharma A/S)
• Inventors: Gonnelli, Robert R., Levesque, Steven F., Standley, Robert L.
• Primary Examiner(s): MAUST, TIMOTHY LEWIS
• Application Number:
  US12/773,679
• Publication Number:
  US 20100276034A1
• Time in Patent Office: 1,407 Days
• Field of Search: 141319-323, 141/329, 141/330, 604/407, 604/414
• US Class Current: 141/322
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2017 having three or more piercing ends
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: B65B 3/26 Methods or devices for controlling the quantity of the material fed or filled
• CPC Class Codes: G01F 11/262 for liquid or semi-liquid
• CPC Class Codes: Y10T 137/8593 Systems

Abstract

A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.

Claims

1. A fluid transfer device comprising:

a metering reservoir;

a manifold forming at least part of a first channel, the first channel fluidly connected with the metering reservoir, the first channel comprising a first cannula extending from the manifold, the manifold forming at least part of a second channel, the second channel fluidly connected with the metering reservoir, the second channel comprising a second cannula extending from the manifold;

a third channel extending through the manifold and comprising a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula;

a first check valve disposed within the first channel; and

a second check valve disposed within the second channel,

wherein the distal end of the first cannula and the first end of the third cannula are configured to fluidly couple to a supply reservoir and the distal end of the second cannula and the second end of the third cannula are configured to fluidly couple to a fill reservoir, and

wherein when the distal end of the first cannula and the first end of the third cannula are fluidly coupled to the supply reservoir, and the distal end of the second cannula and the second end of the third cannula are fluidly coupled to the fill reservoir, expanding the metering reservoir draws fluid from the supply reservoir into the metering reservoir, compressing the metering reservoir expels the fluid from the metering reservoir into the fill reservoir and expelling the fluid into the fill reservoir displaces air in the fill reservoir into the supply reservoir.

2. The fluid transfer device of claim 1, wherein the third cannula extends at least partially through the first cannula.

3. The fluid transfer device of claim 1, wherein the first cannula has a larger cross sectional area than a cross sectional area of the second cannula.

4. The fluid transfer device of claim 1 further comprising:

a supply support configured to couple the fill reservoir with the supply reservoir.

5. The fluid transfer device of claim 4, wherein the supply support includes at least one catch proximate the first cannula and configured to releasably retain the supply reservoir.

6. The fluid transfer device of claim 5, wherein the at least one catch includes at least two catches spaced different distances from the first cannula.

7. The fluid transfer device of claim 4, wherein the supply support includes at least one catch proximate the first cannula and configured to non-releasably retain the supply reservoir.

8. The fluid transfer device of claim 1 further comprising:

a member supporting the second cannula and the second end of the third cannula; and

a tray support connected to the member and configured to align the fill reservoir with the second cannula and the second end of the third cannula.

9. The fluid transfer device of claim 8 further comprising:

a tray slideably connected to the tray support and configured to accommodate the fill reservoir.

10. The fluid transfer device of claim 9, wherein at least one of the tray support and the tray further comprises a safety lock configured to prevent the tray from moving relative to the tray support when the tray is empty and exposing the second cannula.

11. The fluid transfer device of claim 9 further comprising:

a safety reservoir configured to removeably couple with the tray and configured to block access to the second cannula in an initial position.

12. The fluid transfer device of claim 1, wherein the first cannula extends from the manifold in a first direction and the second cannula extends in a second direction from the manifold, the first direction being generally opposite the second direction.

13. The fluid transfer device of claim 12, wherein the metering reservoir extends from the manifold generally in the first direction.

14. The fluid transfer device of claim 1, wherein the metering reservoir includes a plunger.

15. The fluid transfer device of claim 14, wherein the plunger comprises a plunger rod and a plunger tip.

16. The fluid transfer device of claim 1, wherein the metering reservoir has a metering stop.

17. The fluid transfer device of claim 16, wherein the metering stop is adjustable.

18. The fluid transfer device of claim 1, wherein the first cannula is configured to transfer substantially all of the fluid from the supply reservoir.

19. The fluid transfer device of claim 1, wherein the first cannula includes a beveled tip.

20. The fluid transfer device of claim 1, wherein the second cannula includes a beveled tip.

21. The fluid transfer device of claim 1, wherein the second end of the third cannula comprises a beveled tip.

22. The fluid transfer device of claim 1, wherein the third cannula is disposed within the first cannula and the first end of the third cannula is curved toward an inner side wall of the first cannula proximate the distal end of the first cannula.

23. The fluid transfer device of claim 1, wherein the first end of the third cannula and the second end of the third cannula extend in opposite directions and the second cannula extends further from the metering reservoir than the second end of the third cannula.

24. The fluid transfer device of claim 1, wherein the volume of the metering reservoir is larger than the volume of the fill reservoir.

25. The fluid transfer device of claim 1, wherein the volume of the supply reservoir is larger than the volume of the metering reservoir.

26. The fluid transfer device of claim 1, wherein the first and second channels each comprise less than 200 μ

l of fluid transfer space.

27. The fluid transfer device of claim 1, wherein the fill reservoir comprises a fluid delivery device and the supply reservoir comprises a vial.

28. A fluid transfer device comprising:

a metering reservoir;

a manifold forming at least part of a first channel, the first channel fluidly connected with the metering reservoir, the first channel comprising a first cannula extending from the manifold, the manifold forming at least part of a second channel, the second channel fluidly connected with the metering reservoir, the second channel comprising a second cannula extending from the manifold;

a third channel extending through the manifold and comprising a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula, the first end of the third cannula and the distal end of the first cannula extending in a first direction and the second end of the third cannula and the distal end of the second cannula extending in a second direction, the first direction being generally opposite the second direction;

a first check valve disposed within the first channel; and

a second check valve disposed within the second channel.