Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses
First Claim
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1. A method of manufacturing a silicone hydrogel contact lens, comprising:
- forming a silicone hydrogel contact lens body having an anterior surface and a posterior surface, wherein, after hydration in water or an aqueous solution, at least one of the anterior surface and the posterior surface of the lens body when wet is substantially smooth and comprises a plurality of depressions extending inwardly into the lens body from the substantially smooth surface, the plurality of depressions having at least one of an average diameter between about 150 nanometers and less than 1500 nanometers and an average density from about 100 depressions per 900 μ
m2 to about 1200 depressions per 900 μ
m2, and wherein the lens body has not been subjected to a form of plasma treatment, the lens body has not been treated with a polymerizable swelling agent after the lens body is formed, or both, at least one of the anterior surface and the posterior surface of the lens body has an average surface roughness from about 5 nanometers RMS to about 30 nanometers RMS, and the lens body has a swell factor of at least 20%.
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Abstract
Silicone hydrogel contact lenses, when hydrated, have a plurality of depressions on one or more of the lens surfaces. The depressions have a depth less than 1 micrometer, or less than 100 nanometers. The silicone hydrogel contact lenses have not been subject to treatment with plasma. Methods of manufacturing the silicone hydrogel contact lenses are also disclosed.
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Citations
19 Claims
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1. A method of manufacturing a silicone hydrogel contact lens, comprising:
forming a silicone hydrogel contact lens body having an anterior surface and a posterior surface, wherein, after hydration in water or an aqueous solution, at least one of the anterior surface and the posterior surface of the lens body when wet is substantially smooth and comprises a plurality of depressions extending inwardly into the lens body from the substantially smooth surface, the plurality of depressions having at least one of an average diameter between about 150 nanometers and less than 1500 nanometers and an average density from about 100 depressions per 900 μ
m2 to about 1200 depressions per 900 μ
m2, and wherein the lens body has not been subjected to a form of plasma treatment, the lens body has not been treated with a polymerizable swelling agent after the lens body is formed, or both, at least one of the anterior surface and the posterior surface of the lens body has an average surface roughness from about 5 nanometers RMS to about 30 nanometers RMS, and the lens body has a swell factor of at least 20%.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A silicone hydrogel contact lens, comprising:
a silicone hydrogel lens body comprising an anterior surface and a posterior surface, wherein, after hydration in water or an aqueous solution, at least one of the anterior surface and the posterior surface of the lens body when wet is substantially smooth and comprises a plurality of depressions extending inwardly into the lens body from the substantially smooth surface, the plurality of depressions having an average diameter between about 150 nanometers and less than 1500 nanometers, and wherein the lens body has not been subjected to a form of plasma treatment, the lens body has not been treated with a polymerizable swelling agent after the lens body is formed, or both, at least one of the anterior surface and the posterior surface of the lens body has an average surface roughness from about 5 nanometers RMS to about 30 nanometers RMS, and the lens body has a swell factor of at least 20%. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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19. A silicone hydrogel contact lens, comprising:
a non-plasma treated silicone hydrogel lens body comprising an anterior surface and a posterior surface, at least one of the anterior surface and the posterior surface being substantially smooth and comprising a plurality of depressions extending inwardly into the lens body from the substantially smooth surface, the plurality of depressions having an average density from about 100 depressions per 900 μ
m2 to about 1200 depressions per 900 μ
m2, at least one of the anterior surface and the posterior surface of the lens body has an average surface roughness from about 5 nanometers RMS to about 30 nanometers RMS, and the lens body has a swell factor of at least 20%.
Specification