Systems approach to comorbidity assessment
First Claim
1. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform a method for assessing a body system for an emergence of a comorbidity associated with a primary disease, comprising:
- receiving at least one of an autonomic index, a neurologic index, a stress marker index, a psychiatric index, an endocrine index, or a quality of life index of a patient;
comparing the at least one index to at least one reference value associated with the at least one index;
assessing a susceptibility of a the body system to the emergence of the comorbidity at least partially caused by the primary disease based on the comparing, wherein the body system comprises at least one of an autonomic system, a neurologic system, a psychiatric system, an endocrine system, or subsystems of the foregoing; and
providing an output relating to the assessing, wherein the output comprises at least one of increased susceptibility, decreased susceptibility, stable susceptibility, or a determination that a the susceptibility cannot be determined.
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Abstract
Methods, systems, and apparatus for assessing a state of a comorbidity associated with a primary disease are provided. The methods comprise receiving at least one autonomic index, neurologic index, stress marker index, psychiatric index, endocrine index, adverse effect of therapy index, physical fitness index, or quality of life index of a patient; comparing the at least one index to at least one reference value; and assessing a state of a body system of the patient that is a site of the comorbidity, based on the comparison. A computer readable program storage device encoded with instructions that, when executed by a computer, perform the method described above is also provided. A medical device system capable of implementing the method described above is also provided.
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Citations
20 Claims
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1. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform a method for assessing a body system for an emergence of a comorbidity associated with a primary disease, comprising:
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receiving at least one of an autonomic index, a neurologic index, a stress marker index, a psychiatric index, an endocrine index, or a quality of life index of a patient; comparing the at least one index to at least one reference value associated with the at least one index; assessing a susceptibility of a the body system to the emergence of the comorbidity at least partially caused by the primary disease based on the comparing, wherein the body system comprises at least one of an autonomic system, a neurologic system, a psychiatric system, an endocrine system, or subsystems of the foregoing; and providing an output relating to the assessing, wherein the output comprises at least one of increased susceptibility, decreased susceptibility, stable susceptibility, or a determination that a the susceptibility cannot be determined. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 20)
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18. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform a method for assessing a body system for an emergence of a comorbidity associated with a primary disease, comprising:
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receiving a first index selected from the group consisting of an autonomic index, a neurologic index, a stress marker index, a psychiatric index, an endocrine index, a physical fitness index, and a quality of life index of a patient; comparing the first index to at least one reference value associated with the at least first index; assessing a susceptibility of a body system to the emergence of the comorbidity at least partially caused by the primary disease based on the comparing, wherein the body system comprises at least one of an autonomic system, a neurologic system, a psychiatric system, an endocrine system, or subsystems of the foregoing; assessing a state of the patient'"'"'s health based on the assessing the susceptibility of the body system to the emergence of the comorbidity; and providing an output relating to at least one of the assessment of the susceptibility of the body system or the assessment of the state of the patient'"'"'s health, wherein the output comprises at least one of increased susceptibility, decreased susceptibility, stable susceptibility, a determination that the susceptibility of the body system cannot be determined, a stable health state, a poorer health state, an improved health state, or a finding that the state of the patient'"'"'s health cannot be determined.
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19. A medical device system, comprising:
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a body index determination unit capable of determining at least one of an autonomic index, at least one neurologic index, at least one stress marker index, at least one psychiatric index, at least one endocrine index, at least one adverse effect of therapy index, at least one physical fitness index, or at least one quality of life index; an index comparison unit capable of comparing at least one said index with at least one reference value; a body system susceptibility assessment unit capable of assessing a susceptibility of a body system to an emergence of a comorbidity at least partially caused by a primary disease of a patient, wherein the body system comprises at least one of an autonomic system, a neurologic system, a psychiatric system, an endocrine system, an hepatic system, a renal system, a bone marrow system, a skin system, or subsystems of the foregoing; and an output unit capable of providing an output relating to the assessing, wherein the output comprises at least one of increased susceptibility, decreased susceptibility, stable susceptibility, or a determination that a susceptibility of the body system cannot be determined.
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Specification