Prosthesis with a selectively applied bone growth promoting agent

• US 8,679,166 B2
• Filed: 07/13/2012
• Issued: 03/25/2014
• Est. Priority Date: 04/25/2007
• Status: Active Grant

• Current Assignee: Jmea Corporation
• Original Assignee: Jmea Corporation
• Inventors: Bhatnagar, Mohit K., Yeh, Jack Y.
• Primary Examiner(s): Hoffman, Mary
• Assistant Examiner(s): NEGRELLIRODRIGUE, CHRISTINA
• Application Number:
  US13/548,612
• Publication Number:
  US 20120277804A1
• Time in Patent Office: 620 Days
• Field of Search: 606/246, 606280-299, 606/70, 606/71
• US Class Current: 606/298
• CPC Class Codes: A61B 17/7208 Flexible pins, e.g. ENDER pins
• CPC Class Codes: A61B 17/7233 with special means of locking the nail to the bone
• CPC Class Codes: A61B 17/7266 with fingers moving radially outwardly
• CPC Class Codes: A61B 17/80 Cortical plates , i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
• CPC Class Codes: A61B 17/864 hollow, e.g. with socket or cannulated
• CPC Class Codes: A61B 17/866 Material or manufacture
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2002/0081 directly machined on the prosthetic surface, e.g. holes, grooves A61F2/30771 takes precedence

Abstract

An implantable prosthesis system including a selectively applied bone growth promoting agent is disclosed. The types of prostheses which may include a selectively applied bone growth promoting agent include rods, fracture plates, screws, as well as other types of prostheses. Additionally, the structural composition of many types of prostheses may be modified to help induce bone ingrowth and allow for fusion with the implantable prosthesis.

Claims

1. An implantable prosthesis system, comprising:

a fracture plate configured to be attached to a bone;

the fracture plate including a first portion and a second portion along a lower surface;

wherein a bone growth promoting agent is selectively applied to the first portion of the lower surface;

wherein the second portion lacks the bone growth promoting agent;

wherein the fracture plate includes a third portion;

wherein the second and third portions are separated by the first portion;

wherein the bone growth promoting agent is disposed in one of a vertical strip and a diagonal strip in the first portion; and

wherein the second and third portions lack the bone growth promoting agent.

2. The implantable prosthesis system according to claim 1, wherein the fracture plate includes holes.

3. The implantable prosthesis system according to claim 2, wherein each hole extends partially into the lower surface.

4. The implantable prosthesis system according to claim 3, wherein each hole includes a bone growth promoting agent applied to at least one of a side wall surface and a distal wall surface of the each hole.

5. The implantable prosthesis system according to claim 2, wherein the holes are configured to contact a tissue adjacent to the bone.

6. The implantable prosthesis system according to claim 1, wherein the fracture plate includes at least one hole configured to receive a screw.

7. The implantable prosthesis system according to claim 6, wherein the fracture plate includes two holes, each hole being configured to receive a screw.

8. The implantable prosthesis system according to claim 6, wherein the fracture plate includes more than two holes.

9. An implantable prosthesis system, comprising:

a fracture plate configured to be attached to a bone;

the fracture plate including a recess;

a liner disposed within the recess, wherein the liner includes a first portion and a second portion along a lower surface configured to contact the bone;

wherein a bone growth promoting agent is selectively applied to the first portion of the lower surface;

wherein the liner includes a third portion along the lower surface;

wherein the second and third portions are separated by the first portion;

wherein a bone growth promoting agent is disposed in a first design on the first portion;

wherein a bone growth promoting agent is disposed in a second design on the second portion of the lower surface; and

wherein the first design is different from the second design.

10. The implantable prosthesis system according to claim 9, wherein the depth of the recess is approximately equal to the thickness of the liner.

11. The implantable prosthesis system according to claim 9, wherein the liner is a wafer of bone.

12. The implantable prosthesis system according to claim 9, wherein the liner is attached to the fracture plate with an attachment selected from the group consisting essentially of an adhesive, hooks, microscopic hooks, temperature difference, interference fit, a Morris taper, and magnetic features.

15. The implantable prosthesis system according to claim 9, wherein the liner includes a plurality of holes each extending partially into the lower surface.

16. The implantable prosthesis system according to claim 9, wherein a bone growth promoting agent is disposed in the second design on the third portion.

13. An implantable prosthesis system comprising:

a fracture plate configured to be attached to a bone;

the fracture plate including a recess;

a liner disposed within the recess, wherein the liner includes a first portion and a second portion along a lower surface configured to contact the bone;

wherein a bone growth promoting agent is selectively applied to the first portion of the lower surface;

wherein the liner includes a third portion;

wherein the second and third portions are separated by the first portion;

wherein the bone growth promoting agent is disposed in one of a vertical strip and a diagonal strip in the first portion; and

wherein the second and third portions lack the bone growth promoting agent.

14. The implantable prosthesis system according to claim 13, wherein the fracture plate includes a plurality of holes each extending partially into the lower surface.

17. An implantable prosthesis system, comprising:

a fracture plate configured to be attached to a bone;

the fracture plate including a first portion, a second portion, and a third portion along a lower surface;

wherein the first and third portions are separated by the second portion;

wherein a bone growth promoting agent is disposed in a first design on the first portion of the lower surface;

wherein a bone growth promoting agent is disposed in a second design on the second portion of the lower surface; and

wherein the first design is different from the second design.

18. The implantable prosthesis system according to claim 17, wherein a bone growth promoting agent is disposed in the first design on the third portion of the lower surface.

19. The implantable prosthesis system according to claim 18, wherein the first design comprises a striped pattern and the second design comprises a spotted pattern.

20. The implantable prosthesis system according to claim 18, wherein the first design comprises a high density geometric pattern and the second design comprises a low density geometric pattern.

21. An implantable prosthesis system comprising:

a fracture plate configured to be attached to a bone;

the fracture plate including a recess;

a liner disposed within the recess, wherein the liner includes a first portion and a second portion along a lower surface configured to contact the bone;

wherein a bone growth promoting agent is selectively applied to the first portion of the lower surface;

wherein the liner includes a third portion along the lower surface;

wherein the second and third portions are separated by the first portion;

wherein the bone growth promoting agent is disposed in one of a striped pattern, a spotted pattern, and a geometric pattern in the first portion; and

wherein the second and third portions lack the bone growth promoting agent.