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Biosensor with laser-sealed capillary space and method of making

  • US 8,679,853 B2
  • Filed: 07/03/2007
  • Issued: 03/25/2014
  • Est. Priority Date: 06/20/2003
  • Status: Active Grant
First Claim
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1. A method, comprising:

  • depositing a reagent on a base substrate;

    laser welding together the base substrate and a cover layer to form a sample-receiving chamber of a biosensor that contains the reagent, wherein no reagent is deposited where the layers are laser welded together;

    providing continuous webs of the base substrate and the cover layer;

    wherein said laser welding includes laser welding together the continuous webs of the base substrate and the cover layer to form a laminate, wherein the laminate includes multiple sample-receiving chambers containing the reagent;

    rotating a rotary-type mask as the continuous webs of the base substrate and the cover layer move thereby, wherein the rotary-type mask includes a plurality of mask apertures that form laser welding patterns for said laser welding;

    wherein said laser welding includes shining a laser beam through at least one of the mask apertures to form a laser weld in the shape of one of the laser welding patterns between the continuous webs;

    wherein one of the base substrate and the cover layer is more transparent than the other; and

    wherein said laser welding includes laser welding through the one that is more transparent by directing a laser beam through the one that is more transparent.

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