Apparatus and method for determining the relative position and orientation of neurostimulation leads

• US 8,682,447 B2
• Filed: 01/30/2006
• Issued: 03/25/2014
• Est. Priority Date: 12/04/2001
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Bradley, Kerry, Thacker, James R.
• Primary Examiner(s): GETZOW, SCOTT M
• Application Number:
  US11/343,007
• Publication Number:
  US 20060122654A1
• Time in Patent Office: 2,976 Days
• Field of Search: 607 59- 62, 607/27, 607/28, 607/117, 607/43, 607/2
• US Class Current: 607/62
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes

Abstract

Interelectrode impedance or electric field potential measurements are used to determine the relative orientation of one lead to other leads in the spinal column or other body/tissue location. Interelectrode impedance is determined by measuring impedance vectors. The value of the impedance vector is due primarily to the electrode-electrolyte interface, and the bulk impedance between the electrodes. The bulk impedance between the electrodes is, in turn, made up of (1) the impedance of the tissue adjacent to the electrodes, and (2) the impedance of the tissue between the electrodes. In one embodiment, the present invention makes both monopolar and bipolar impedance measurements, and then corrects the bipolar impedance measurements using the monopolar measurements to eliminate the effect of the impedance of the tissue adjacent the electrodes. The orientation and position of the leads may be inferred from the relative minima of the corrected bipolar impedance values. These corrected impedance values may also be mapped and stored to facilitate a comparison with subsequent corrected impedance measurement values.

Claims

1. A method, comprising:

determining, using circuitry, a relative two-dimensional orientation of first and second multiple-electrode leads implanted within a user;

conveying electrical stimulation energy from a pulse generator implanted within the user into tissue of the user via the first and second multiple-electrode leads; and

displaying the relative two-dimensional orientation of the first and second multiple-electrode leads.

2. A method as claimed in claim 1, wherein determining the relative two-dimensional orientation of first and second multiple-electrode leads comprises measuring impedance vectors between lead electrodes and inferring the relative two-dimensional orientation of the leads by the relative minima of the impedance vectors.

3. A method as claimed in claim 1, wherein determining the relative two-dimensional orientation of the first and second multiple-electrode leads comprises measuring impedance vectors between respective electrode pairs that each include one of the electrodes on the first multiple-electrode lead and one of the electrodes on the second multiple-electrode lead.

4. A method as claimed in claim 1, wherein determining the relative two-dimensional orientation of first and second multiple-electrode leads comprises applying a stimulus to a selected group of lead electrodes and measuring the voltage at the electrodes not included in the group of electrodes to which the stimulus is applied.

5. A method as claimed in claim 1, wherein displaying the relative two-dimensional orientation of the first and second multiple-electrode leads comprises displaying the relative two-dimensional orientation of the first and second multiple-electrode leads on a programmer display.

6. A method as claimed in claim 1, further comprising:

comparing the displayed relative two-dimensional orientation of the first and second multiple-electrode leads with a display of a previously measured relative two-dimensional orientation of the first and second multiple-electrode leads.

7. A method as claimed in claim 1, further comprising:

comparing the displayed relative two-dimensional orientation of the first and second multiple-electrode leads with a display of a previously entered relative two-dimensional orientation of the first and second multiple-electrode leads.

8. An apparatus as claimed in claim 7, wherein the means for determining the relative two-dimensional orientation comprises means to determine the distances between two or more electrodes carried by the first lead and two or more electrodes carried by the second lead.

9. A method as claimed in claim 1, wherein determining the relative two-dimensional orientation comprises determining the distances between two or more electrodes carried by the first lead and two or more electrodes carried by the second lead.

10. An apparatus for use with first and second implantable leads that include respective pluralities of electrodes, the apparatus comprising:

an implantable pulse generator configured for conveying electrical stimulation energy to the first and second leads;

means for determining a relative two-dimensional orientation of the first and second leads; and

means for displaying the relative two-dimensional orientation of the first and second leads.

11. An apparatus as claimed in claim 10, further comprising:

means for comparing the displayed relative two-dimensional orientation of the first and second leads with a display of a previously measured relative two-dimensional orientation of the first and second leads.

12. An apparatus as claimed in claim 10, further comprising:

means for comparing the displayed relative two-dimensional orientation of the first and second leads with a display of a previously entered relative two-dimensional orientation of the first and second leads.

13. An apparatus for use with first and second implantable leads that include respective pluralities of electrodes, the apparatus comprising:

an implantable pulse generator configured for conveying electrical stimulation energy to the first and second leads;

a display;

circuitry to determine a relative two-dimensional orientation of the first and second leads; and

circuitry to display the relative two-dimensional orientation of the first and second leads on the display.

14. An apparatus as claimed in claim 13, wherein the display is associated with a programmer.

15. An apparatus as claimed in claim 13, wherein the circuitry to determine the relative two-dimensional orientation comprises circuitry to measure impedance vectors between lead electrodes and infer the relative two-dimensional orientation of the leads by the relative minima of the impedance vectors.

16. An apparatus as claimed in claim 13, wherein the circuitry to determine the relative two-dimensional orientation comprises circuitry to measure impedance vectors between respective electrode pairs that each include one of the electrodes on the first lead and one of the electrodes on the second lead.

17. An apparatus as claimed in claim 13, wherein the circuitry to determine the relative two-dimensional orientation comprises circuitry to apply a stimulus to a selected group of lead electrodes and measure the voltage at the electrodes not included in the group of electrodes to which the stimulus is applied.

18. An apparatus as claimed in claim 13, further comprising:

circuitry to compare the displayed relative two-dimensional orientation of the first and second leads with a display of a previously measured relative two-dimensional orientation of the first and second leads.

19. An apparatus as claimed in claim 13, further comprising:

circuitry to compare the displayed relative two-dimensional orientation of the first and second leads with a display of a previously entered relative two-dimensional orientation of the first and second leads.

20. An apparatus as claimed in claim 13, wherein the circuitry to determine the relative two-dimensional orientation comprises circuitry to determine the distances between two or more electrodes carried by the first lead and two or more electrodes carried by the second lead.