Glucagon analogues
First Claim
Patent Images
1. A compound having the formula R1-X-Z-R2 whereinR1 is H, C1-4 alkyl, acetyl, formyl, benzoyl or trifluoroacetyl;
- R2 is OH or NH2;
X is a peptide which has the formula I;
1 Assignment
0 Petitions
Accused Products
Abstract
The invention provides materials and methods for promoting weight loss or preventing weight gain, and in the treatment of diabetes, metabolic syndrome and associated disorders. In particular, the invention provides novel glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
-
Citations
37 Claims
-
1. A compound having the formula R1-X-Z-R2
wherein R1 is H, C1-4 alkyl, acetyl, formyl, benzoyl or trifluoroacetyl; -
R2 is OH or NH2; X is a peptide which has the formula I; - View Dependent Claims (3, 4, 6, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 37)
-
-
2. A compound having the formula R1-X-Z-R2
wherein R1 is H, C1-4 alkyl, acetyl, formyl, benzoyl or trifluoroacetyl; -
R2 is OH or NH2; X is a peptide which has the formula I; - View Dependent Claims (5, 7, 36)
-
Specification