Charged particle cancer therapy patient positioning method and apparatus

• US 8,688,197 B2
• Filed: 05/21/2009
• Issued: 04/01/2014
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Yegorovich Balakin
• Inventors: Balakin, Vladimir Yegorovich
• Primary Examiner(s): Chen, Tse
• Assistant Examiner(s): Brutus, Joel F
• Application Number:
  US12/994,125
• Publication Number:
  US 20110218430A1
• Time in Patent Office: 1,776 Days
• Field of Search: 600/427, 378/65, 378/95, 378/205
• US Class Current: 600/427
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/10 X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy A61N5/01 takes precedence
• CPC Class Codes: G03B 42/02 using X-rays
• CPC Class Codes: G21K 1/087 by electrical means
• CPC Class Codes: G21K 1/093 by magnetic means
• CPC Class Codes: G21K 1/14 using charge exchange devices, e.g. for neutralising or changing the sign of the electrical charges of beams producing or accelerating neutral particle beams H05H3/00
• CPC Class Codes: H01J 3/14 Arrangements for focusing or reflecting ray or beam H01J3/02, H01J3/04 take precedence
• CPC Class Codes: H01J 3/34 along a circle, spiral, or rotating radial line
• CPC Class Codes: H05H 13/04 Synchrotrons
• CPC Class Codes: H05H 7/04 Magnet systems , e.g. undulators, wigglers free-electron laser H01S3/0903; Energisation thereof
• CPC Class Codes: H05H 7/08 Arrangements for injecting particles into orbits
• CPC Class Codes: H05H 7/10 Arrangements for ejecting particles from orbits

Abstract

The invention comprises a patient positioning and/or repositioning system, such as a laying, semi-vertical, or seated patient positioning, alignment, and/or control method and apparatus used in conjunction with multi-axis charged particle radiation therapy. Patient positioning constraints optionally include one or more of: a seat support, a back support, a head support, an arm support, a knee support, and a foot support. One or more of the positioning constraints are preferably movable and/or under computer control for rapid positioning, repositioning, and/or immobilization of the patient. The system optionally uses an X-ray beam that lies in substantially the same path as a proton beam path of a particle beam cancer therapy system. The generated image is usable for: fine tuning body alignment relative to the proton beam path, to control the charged particle beam path to accurately and precisely target the tumor, and/or in system verification and validation.

Claims

1. A method for positioning a tumor of a patient for treatment with positively charged particles, comprising the steps of:

positioning the patient with a patient positioning system, said patient positioning system comprising an upper body support, wherein said upper body support comprises a semi-upright patient support surface;

after said step of positioning, collecting multi-field images of the tumor in the patient;

developing a tumor irradiation plan;

repositioning the tumor using said patient positioning system;

after said step of repositioning, verifying position of the tumor;

irradiating the tumor of the patient with the positively charged particles from a charged particle system, said charged particle system comprising a charged particle beam path, said charge particle beam path passing within about six inches of said semi-upright patient support surface;

repeating said step of irradiating in at least four rotation positions;

controlling an energy of the charged particle using an accelerator in said charged particle system, said accelerator comprising;

a set of at least ten coils;

a set of at least ten wire loops; and

a set of at least ten microcircuits, each of said at least ten microcircuits integrated to a corresponding one of said at least ten wire loops, wherein each of said at least ten wire loops completes at least one turn about at least one of said at least ten coils; and

using a radio-frequency synthesizer, sending a low voltage signal to each of said at least ten microcircuits, each of said at least ten microcircuits amplifying said low voltage signal yielding an acceleration voltage.

2. The method of claim 1, further comprising the step of:

timing delivery of the charged particles to the tumor using a respiration monitor.

3. The method of claim 1, further comprising the step of:

varying intensity of the charged particles dependent upon efficiency, wherein efficiency is a comparison of;

(1) delivery of energy of the charged particles within the tumor and (2) delivery of energy of the charged particles to healthy tissue of the patient.

4. The method of claim 1, further comprising the step of:

increasing an intensity of the charged particles when targeting a distal portion of the tumor, wherein said distal portion of said tumor changes with rotation of the patient on a platform rotating to as least ten distinct rotational positions in a period of less than one minute during irradiation of the tumor by the charged particles, said platform holding the patient.

5. The method of claim 1, further comprising the steps of:

horizontally controlling the charged particles;

vertically controlling the charged particles; and

providing an X-ray input signal, wherein said X-ray input signal comprises a signal generated by an X-ray source proximate the charged particle beam;

wherein both said step of horizontally controlling and said step of vertically controlling use said X-ray input signal.

6. A method for positioning a tumor of a patient for treatment with positively charged particles, comprising the steps of:

positioning the patient with a patient positioning system, said patient positioning system comprising an upper body support, wherein said upper body support comprises a semi-upright patient support surface;

after said step of positioning, collecting multi-field images of the tumor in the patient;

developing a tumor irradiation plan;

repositioning the tumor using said patient positioning system;

after said step of repositioning, verifying position of the tumor;

irradiating the tumor of the patient with the positively charged particles from a charged particle system, said charged particle system comprising a charged particle beam path, said charge particle beam path passing within about six inches of said semi-upright patient support surface;

repeating said step of irradiating in at least four rotation positions; and

controlling a magnetic field in a bending magnet of a synchrotron in said charged particle system, said bending magnet comprising;

a tapered iron based core adjacent a gap, said tapered iron based core comprising a surface polish of less than about ten microns roughness; and

a focusing geometry comprising;

a first cross-sectional distance of said tapered iron based core forming an edge of said gap,

a second cross-sectional distance of said iron based core not in contact with said gap, wherein said second cross-sectional distance is at least fifty percent larger than said first cross-sectional distance, said first cross-sectional distance running parallel said second cross-sectional distance.