Method and apparatus for identifying cardiac risk
First Claim
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1. A method for computing a cardiac-based metric, the method comprising:
- for each of a plurality of cardiac cycles of a subject,identifying the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle, andidentifying the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle; and
computing the cardiac-based metric based upon a time difference between the end of the mechanical systole and the end of the electrical systole in each of the plurality of cardiac cycles.
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Abstract
A cardiac-based metric is computed based upon characteristics of a subject'"'"'s cardiac function. In accordance with one or more embodiments, the end of a mechanical systole is identified for each of a plurality of cardiac cycles of a subject, based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle. The end of an electrical systole of an electrocardiogram (ECG) signal for each cardiac cycle is also identified. A cardiac-based metric is computed, based upon a time difference between the end of the electrical systole and the end of the mechanical systole, for the respective cardiac cycles.
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Citations
25 Claims
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1. A method for computing a cardiac-based metric, the method comprising:
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for each of a plurality of cardiac cycles of a subject, identifying the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle, and identifying the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle; and computing the cardiac-based metric based upon a time difference between the end of the mechanical systole and the end of the electrical systole in each of the plurality of cardiac cycles. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. An apparatus for computing a cardiac-based metric of a subject using signal data for a plurality of cardiac cycles, the apparatus including:
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a first module configured and arranged to identify the end of a mechanical systole based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle; a second module configured and arranged to identify the end of an electrical systole of an electrocardiogram (ECG) signal for the cardiac cycle; and a third module configured and arranged to compute the cardiac-based metric based upon a time difference between the end of the mechanical systole and the end of the electrical systole in each of the cardiac cycles. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A method for computing a metric indicative of arrhythmic risk, the method comprising:
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computing beat-to-beat values of a subject'"'"'s cardiac function based on at least one of;
an electromechanical window corresponding to a time between the end of a mechanical systole and the end of an electrical systole of the subject'"'"'s heart, a QT interval corresponding to a time between the start of a Q wave and the end of a T wave of an ECG of the subject, and an R-R interval of the ECG;computing a time series for each of successive lags of the beat-to-beat values by applying a low-pass filter and decimator to the beat-to-beat values; computing a trend of the variability of the time series by using one of sample entropy, long-term instability, short-term instability, and variance; and evaluating arrhythmic risk based upon the computed trend. - View Dependent Claims (25)
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Specification