Automated analysis of data collected by in-vivo devices

• US 8,688,467 B2
• Filed: 01/09/2009
• Issued: 04/01/2014
• Est. Priority Date: 01/09/2009
• Status: Active Grant

• Current Assignee: Cerner Innovation, Inc. (Oracle Corporation)
• Original Assignee: Cerner Innovation, Inc. (Oracle Corporation)
• Inventors: Cross, Lori N., Devers, Daniel P., Hauck, Arthur J., Harrison, Kyle R., Hernandez, Carlos, Miner, Travis, Jimenez, Timothy
• Primary Examiner(s): Gort, Elaine
• Assistant Examiner(s): Ng, Jonathan K
• Application Number:
  US12/351,612
• Publication Number:
  US 20100179820A1
• Time in Patent Office: 1,908 Days
• Field of Search: None
• US Class Current: 705/2
• CPC Class Codes: G06Q 10/10 Office automation; Time management
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 40/60 for the operation of medical equipment or devices
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Systems and methods for operably coupling medical device(s) together with an evaluation device such that closed-loop processing may occur are provided. To achieve closed-loop processing, the evaluation device is configured to receive diagnostic information related to physiological attributes of a patient and operational-status information of the medical device(s). Upon receipt of this information, the evaluation device may automatically analyze the data and automatically compose instructions based on the analysis. Analyzing includes comparing the data against content within an electronic medical record (EMR) or applying rules to the data. The rules are built on evidence-based medical procedures consistent with current medical practice. The instructions, when distributed and implemented, invoke actions at the medical device(s), such as dispensing a medication and reprogramming configuration settings, as well as actions at a notification component configured to request a healthcare professional to intervene in a patient'"'"'s treatment and to provide feedback of medical events.

Claims

1. One or more computer-readable media accommodated by an evaluation device having computer-useable instructions embodied thereon that, when executed, perform a method for observing and analyzing physiological attributes of a patient, wherein the method comprises:

receiving diagnostic information from an in-vivo device at the evaluation device wherein the diagnostic information characterizes, in part, the physiological attributes of the patient attained by monitoring the patient utilizing the in-vivo device;

accessing an electronic medical record (EMR) that is associated with the patient, wherein the EMR includes medical information that describes the patient'"'"'s medical history and interactions with healthcare systems;

inspecting the EMR to discover content within the medical information that is relevant to the received diagnostic information;

accessing rules that are derived from evidence-based medical procedures;

amending a treatment being administered to the patient as a function of the relevant content and the received diagnostic information in view of the rules;

automatically causing the in-vivo device to implement the amended treatment, wherein the in-vivo device and the EMR participate in a closed-loop system that self-regulates the treatment of the patient;

upon the in-vivo device implementing the amended treatment, providing a notice from the evaluation device to the patient'"'"'s insurance company that a new medication, more of a current medication, or a comparable generic medication is necessary for proper treatment of the patient;

receiving operational-status information from the in-vivo device at the evaluation device, wherein the operational-status information characterizes functional aspects of the in-vivo device;

comparing the functional aspects read from the operational-status information against device specifications accessed from a dynamically updatable source;

when the functional aspects fail to satisfy the device specifications upon comparison, causing configuration settings within the in-vivo device to be adjusted based on, in part, the device specifications;

invoking adjustment of the configuration settings of the in-vivo device by causing testing criteria within the configuration settings to be reprogrammed in accordance with the device specifications to influence either a dosage or frequency of medication being dispensed to the patient by the in-vivo device, wherein reprogramming the testing criteria affects a quality of the diagnostic information received from the in-vivo device, wherein the in-vivo device and the evaluation device participate in a closed-loop system that self-regulates the testing criteria employed by the in-vivo device;

receiving updated physiological attributes of the patient attained by monitoring the patient in accordance with the reprogrammed testing criteria.

2. The computer-readable media of claim 1, wherein the patient'"'"'s medical information of the EMR comprises predefined values that are derived from expected physical attributes of the patient, and wherein comparatively evaluating the data against the patient'"'"'s medical information of the EMR comprises:

comparing the diagnostic information against the predefined values;

based on the comparison, ascertaining that the diagnostic information fails to satisfy the predefined values; and

providing a notification of the failure.

3. The computer-readable media of claim 2, wherein causing the in-vivo device to implement the amended treatment comprises instructing the in-vivo device to administer the amended treatment to the patient.

4. The computer-readable media of claim 1, wherein the dynamically updatable source includes an information store that maintains the predetermined device specifications, and wherein the predetermined device specifications include predefined properties of the in-vivo device.

5. The computer-readable media of claim 4, wherein causing the in-vivo device to implement the amended treatment further comprises:

examining medical-device events within the operational-status information to identify whether the in-vivo device has encountered a failure; and

incident to the examination, issuing a command to reprogram the in-vivo device.

6. The computer-readable media of claim 1, wherein reprogramming testing criteria of the in-vivo device comprises causing the in-vivo device to adjust a sampling frequency of the physiological attributes of the patient.

7. The computer-readable media of claim 6, the method further comprising determining whether to accept the data from the in-vivo device, wherein the process of determining comprises:

ascertaining that a format of the data received from the in-vivo device is incompatible with an expected format;

temporarily storing the incompatibly formatted data in a memory location; and

attempting to adjust the incompatible format of the data being communicated from the in-vivo device to align with the expected format.

8. The computer-readable media of claim 7, wherein the process of determining whether to accept the data from the in-vivo device further comprises performing a quality control process to validate the data is being communicated from the in-vivo device, and wherein the quality control process comprises:

reading the configuration settings of the in-vivo device from the operational-status information; and

confirming that the data is accurate based on the configuration settings.

9. The computer-readable media of claim 8, wherein the process of determining whether to accept the data from the in-vivo device further comprises performing an authentication process comprising:

verifying the in-vivo device is a source of the data; and

decoding a security measure imposed by the in-vivo device to protect impermissible access of the data.

10. The computer-readable media of claim 1, wherein the method further comprises primarily establishing a wireless connection between the in-vivo device and the evaluation device for receiving the data.

11. The computer-readable media of claim 10, wherein the method further comprises, upon detecting a disruption in a network carrying the wireless communication, exercising an auxiliary connection to resume communication of the data between the in-vivo device and the evaluation device.

12. The computer-readable media of claim 11, wherein the data is received by the evaluation device according to a communication scheme, wherein the communication scheme instructs the in-vivo device to transmit the data in real time, at regular intervals, or upon the issuance of a request for data.

13. The computer-readable media of claim 1, wherein reprogramming testing criteria of the in-vivo device comprises causing the in-vivo device to adjust which physiological attributes of the patient to monitor.

14. A computerized method for automatically invoking one or more actions based on an analysis of data communicated from an in-vivo device, wherein the method comprises:

receiving diagnostic information from the in-vivo device at an evaluation device wherein the diagnostic information characterizes, in part, physiological attributes of a patient attained by monitoring the patient utilizing the in-vivo device;

accessing rules that are derived from evidence-based medical procedures;

amending a treatment being administered to the patient as a function of the received diagnostic information in view of the rules;

automatically causing the in-vivo device to implement the amended treatment;

upon automatically causing the in-vivo device to implement the amended treatment, providing a notice from the evaluation device to the patient'"'"'s insurance company that a new medication, more of a current medication, or a comparable generic medication is necessary for proper treatment of the patient;

receiving operational-status information communicated from the in-vivo device, wherein the operational-status information describes an operational status of the in-vivo device that is internally implanted within a patient, and wherein the operational status corresponds with device specifications of the in-vivo device maintained at a dynamically updatable source;

accessing the dynamically updateable source that maintains the device specifications;

recognizing that an update to the device specifications has occurred, wherein the updated device specifications are based on, in part, the physiological attributes of the patient attained by monitoring the patient utilizing the in-vivo device;

automatically analyzing the operational-status information by employing a clinical procedure that comprises;

(a) accessing the updated device specifications maintained at the dynamically updatable source;

(b) comparing the operational-status information of the in-vivo device against the updated device specifications; and

(c) upon comparison, determining that the operational-status information of the in-vivo device does not correspond with the updated device specifications; and

automatically reprogramming configuration settings stored on the in-vivo device to reflect the updated device specifications, wherein the configuration settings influence either a dosage or frequency of medication being dispensed to the patient by the in-vivo device, and wherein the in-vivo device and the dynamically updatable source participate in a closed-loop system that self-regulates the configuration settings of the in-vivo device.