Analyzer for measuring blood gas parameters

• US 8,690,774 B2
• Filed: 11/19/2008
• Issued: 04/08/2014
• Est. Priority Date: 05/31/2002
• Status: Expired due to Fees

• Current Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Ruether, Horst, Huemer, Herfried
• Primary Examiner(s): Mallari, Patricia
• Assistant Examiner(s): JANG, CHRISTIAN YONGKYUN
• Application Number:
  US12/273,749
• Publication Number:
  US 20090163792A1
• Time in Patent Office: 1,966 Days
• Field of Search: 600/353, 600/364, 600/549, 422/81, 604 401- 606, 604/6.13, 604403-410, 604/415
• US Class Current: 600/364
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: G01N 33/4925 measuring blood gas content, e.g. O2, CO2 , HCO3

Abstract

The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO₂, and pO₂, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Claims

1. An analyzer comprising:

at least one measuring cell;

a temperature sensor for measuring the temperature of the measuring cell;

elements for heating and cooling the measuring cell;

a regulating unit for adjusting the temperature of the measuring cell to the temperature of a patient or blood sample upon sample withdrawal;

a temperature probe for measuring the temperature of the patient or blood sample, wherein the regulating unit is connected to the temperature probe via a cable or wireless link for data transmission from the probe to the regulating unit; and

a locking device on a sample input element, wherein the regulating unit enables sample input only when the measuring cell temperature is equal to the blood sample temperature or patient temperature.

2. The analyzer of claim 1, wherein the wireless link comprises an infrared or a radio frequency signal.

3. The analyzer of claim 1, wherein the regulating unit is configured to adjust the temperature of the measuring cell between about 22 and about 40°

C.

4. The analyzer of claim 1 further comprising an electrochemical measurement electrode configured for measuring at least one blood gas parameter in the blood sample, wherein the blood gas parameter is selected from pH, pCO₂, pO₂, and combinations thereof.

5. An analyzer comprising:

at least one measuring cell;

a temperature sensor for measuring the temperature of the measuring cell;

elements for heating and cooling the measuring cell;

a regulating unit for adjusting the temperature of the measuring cell to the temperature of a patient or blood sample upon sample withdrawal; and

a temperature probe for measuring the temperature of the patient or blood sample, wherein

the regulating unit is connected to the temperature probe via a cable or wireless link for data transmission from the probe to the regulating unit, and

the analyzer enables the blood sample to enter the measuring cell only if the temperature of the measuring cell is substantially equal to the measured temperature of the patient or blood sample upon sample withdrawal.

6. The analyzer of claim 5, wherein the temperature of the measuring cell is adjusted to the measured temperature of the patient or blood sample upon sample withdrawal, before the analyzer enables the blood sample to enter the measuring cell.

7. An analyzer comprising:

at least one measuring cell;

a temperature sensor for measuring the temperature of the measuring cell;

elements for heating and cooling the measuring cell;

a regulating unit for adjusting the temperature of the measuring cell to the temperature of a patient or blood sample upon sample withdrawal; and

a temperature probe for continuously measuring the temperature of the patient or blood sample, wherein

the regulating unit is connected to the temperature probe via a cable or wireless link for data transmission from the probe to the regulating unit, and

the regulating unit is configured to continually adjust the temperature of the measuring cell synchronously with the measured temperature of the patient.