Direct assay of cholesterol in skin removed by tape stripping
First Claim
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1. A tape stripping device for use in obtaining skin samples, the device comprising:
- a) a sampling member including an interior surface and an outer surface, either the interior surface or the outer surface including releasable sections of the sampling member;
b) the releasable sections delineated by indentations in the sampling member;
c) a tape provided on the interior surface of the sampling member, the tape covering at least a portion of a plurality of the releasable sections, the tape having a medical skin stripping adhesive presented away from the interior surface; and
d) a closure member adapted to engage the sampling member and seal the tape within the device.
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Abstract
Skin cholesterol is measured by applying an adhesive tape onto a selected area of the skin to adhere the tape to the selected skin area and stripping the tape off the selected skin area to obtain a sample representative of the outer stratum corneum layer of the skin, the sample adhering to the tape so as to have exposed skin constituents. The sample is assayed using a detector reagent that specifically binds to cholesterol and in addition has an indicator component that allows quantitation of the amount of cholesterol present in the exposed skin constituents.
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16 Claims
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1. A tape stripping device for use in obtaining skin samples, the device comprising:
- a) a sampling member including an interior surface and an outer surface, either the interior surface or the outer surface including releasable sections of the sampling member;
b) the releasable sections delineated by indentations in the sampling member;
c) a tape provided on the interior surface of the sampling member, the tape covering at least a portion of a plurality of the releasable sections, the tape having a medical skin stripping adhesive presented away from the interior surface; and
d) a closure member adapted to engage the sampling member and seal the tape within the device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- a) a sampling member including an interior surface and an outer surface, either the interior surface or the outer surface including releasable sections of the sampling member;
Specification