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Composition and process for bone growth and repair

  • US 8,690,874 B2
  • Filed: 08/03/2010
  • Issued: 04/08/2014
  • Est. Priority Date: 12/22/2000
  • Status: Expired due to Fees
First Claim
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1. A bone graft composition comprising:

  • particles of dehydrothermally cross-linked substrate including about 25 wt. % to about 40 wt. % bovine Type I dehydrothermally cross-linked dermal collagen and about 60 wt. % to about 75 wt. % calcium hydrogen phosphate, wherein the particles were prepared from a lyophilized composition of collagen and calcium hydrogen phosphate; and

    a fluid selected from the group consisting of bone marrow aspirate, whole blood or combinations thereof,wherein the composition comprises about 2 to about 150 parts by weight of fluid.

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