Gallium-containing sealant for medical use
First Claim
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1. A polymeric medical sealant article of manufacture, the medical sealant article comprising a protective layer that contacts a deciliated mucosal tissue portion from which a biofilm has been removed, and the protective layer comprising sufficient polymeric film-former and sufficient gallium-containing antimicrobial agent to reduce biofilm reformation on such tissue portion.
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Abstract
Chronic rhinosinusitis and other bacterial sinus conditions may be treated by applying a solvating system containing a surfactant to a bacterial biofilm in a nasal or sinus cavity, disrupting the biofilm, and applying a protective layer of a polymeric film-forming medical sealant.
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14 Claims
- 1. A polymeric medical sealant article of manufacture, the medical sealant article comprising a protective layer that contacts a deciliated mucosal tissue portion from which a biofilm has been removed, and the protective layer comprising sufficient polymeric film-former and sufficient gallium-containing antimicrobial agent to reduce biofilm reformation on such tissue portion.
Specification