Medical image processing device, method and program

• US 8,693,753 B2
• Filed: 09/27/2012
• Issued: 04/08/2014
• Est. Priority Date: 09/30/2011
• Status: Active Grant

• Current Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Original Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Inventors: Nakamura, Keigo
• Primary Examiner(s): Drennan, Barry
• Assistant Examiner(s): Mistry, Oneal R
• Application Number:
  US13/629,232
• Publication Number:
  US 20130083982A1
• Time in Patent Office: 558 Days
• Field of Search: 382128-134
• US Class Current: 382/128
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/20164 Salient point detection; Corner detection
• CPC Class Codes: G06T 2207/30048 Heart; Cardiac
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G06T 7/12 Edge-based segmentation
• CPC Class Codes: G06T 7/149 involving deformable models, e.g. active contour models
• CPC Class Codes: G06V 10/248 by interactive preprocessing or interactive shape modelling, e.g. feature points assigned by a user
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS

Abstract

A medical image processing device for extracting an endocardium of a left ventricle from 3D image data representing the left ventricle is provided. The device includes: a blood region extracting unit to extract a blood region in the left ventricle from the image data; a convex and concave points identifying unit to find a convex hull from sample points on a contour of the extracted blood region and identify convex points forming the convex hull and concave points, which are sample points other than the convex points; and an endocardium determining unit to deform the contour of the blood region by moving at least a part of the concave points outward from the blood region by an amount determined based on a positional relationship among each concave point and the convex points located around the concave point and determine a deformed contour of the blood region to be the endocardium.

Claims

1. A medical image processing device for extracting an endocardium of a left ventricle from 3D image data representing the left ventricle, the device comprising:

a blood region extracting unit configured to extract a blood region in the left ventricle from the image data;

a convex and concave points identifying unit configured to find a convex hull from a plurality of sample points on a contour of the extracted blood region and identify convex points forming the convex hull and concave points, which are sample points other than the convex points; and

an endocardium determining unit configured to deform the contour of the blood region by moving at least a part of the concave points outward from the blood region by an amount determined based on a positional relationship among each concave point and the convex points located around the concave point and determine a deformed contour of the blood region to be the endocardium.

2. The medical image processing device as claimed in claim 1, wherein

the convex and concave points identifying unit identifies the convex points forming the convex hull and the concave points, which are the sample points other than the convex points, by finding the convex hull from the sample points on the contour of the extracted blood region in each of pieces of 2D image data representing cross sections perpendicular to an axis passing through a base and an apex of a heart set in the left ventricle;

and

the endocardium determining unit obtains, in each of the pieces of 2D image data, a deformed contour of the blood region deformed by moving at least a part of the concave points outward from the blood region based on a positional relationship among each concave point and the convex points located on both sides of the concave point, and determines the endocardium based on the deformed contour.

3. The medical image processing device as claimed in claim 1, wherein, when the concave point to be moved is present within a predetermined range from a base of a heart along a direction of an axis passing through the base and an apex of the heart set in the left ventricle, the endocardium determining unit makes a degree of the movement of the concave point smaller than that in a case where the concave point to be moved is present outside the range.

4. The medical image processing device as claimed in claim 1, wherein, when the concave point to be moved is present within a predetermined range containing a central area between a base and an apex of a heart set in advance along a direction of an axis passing through the base and the apex of the heart set in the left ventricle, the endocardium determining unit makes a degree of the movement of the concave point larger than that in a case where the concave point to be moved is present outside the range.

5. The medical image processing device as claimed in claim 1, wherein the endocardium determining unit makes a degree of the movement of the concave point smaller as an angle formed between straight lines respectively connecting an arbitrary point set in a central area between the blood region with convex points located around the concave point is larger.

6. The medical image processing device as claimed in claim 1, further comprising an epicardium extracting unit configured to extract an epicardium of the left ventricle from the image data,

wherein the endocardium determining unit moves at least the part of the concave points with setting an upper limit of the movement at a position at a predetermined distance inward from the extracted epicardium.

7. A medical image processing method for extracting an endocardium of a left ventricle from 3D image data representing the left ventricle, the method comprising the steps of:

extracting a blood region in the left ventricle from the image data;

finding a convex hull from a plurality of sample points on a contour of the extracted blood region and identifying convex points forming the convex hull and concave points, which are sample points other than the convex points; and

deforming the contour of the blood region by moving at least a part of the concave points outward from the blood region by an amount determined based on a positional relationship among each concave point and the convex points located around the concave point and determining a deformed contour of the blood region to be the endocardium.

8. The medical image processing method as claimed in claim 7, wherein the step of identifying the convex and concave points comprises identifying the convex points forming the convex hull and the concave points, which are the sample points other than the convex points, by finding the convex hull from the sample points on the contour of the extracted blood region in each of pieces of 2D image data representing cross sections perpendicular to an axis passing through a base and an apex of a heart set in the left ventricle;

and

the step of determining the endocardium comprises obtaining, in each of the pieces of 2D image data, a deformed contour of the blood region deformed by moving at least a part of the concave points outward from the blood region based on a positional relationship among each concave point and the convex points located on both sides of the concave point, and determining the endocardium based on the deformed contour.

9. The medical image processing method as claimed in claim 7, wherein the step of determining the endocardium comprises, when the concave point to be moved is present within a predetermined range from a base of a heart along a direction of an axis passing through the base and an apex of the heart set in the left ventricle, making a degree of the movement of the concave point smaller than that in a case where the concave point to be moved is present outside the range.

10. The medical image processing method as claimed in claim 7, wherein the step of determining the endocardium comprises, when the concave point to be moved is present within a predetermined range containing a central area between a base and an apex of a heart set in advance along a direction of an axis passing through the base and the apex of the heart set in the left ventricle, making a degree of the movement of the concave point larger than that in a case where the concave point to be moved is present outside the range.

11. The medical image processing method as claimed in claim 7, wherein the step of determining the endocardium comprises making a degree of the movement of the concave point smaller as an angle formed between straight lines respectively connecting an arbitrary point set in a central area between the blood region with convex points located around the concave point is larger.

12. The medical image processing method as claimed in claim 7, further comprising extracting an epicardium of the left ventricle from the image data,

wherein the step of determining the endocardium comprises moving at least the part of the concave points with setting an upper limit of the movement at a position at a predetermined distance inward from the extracted epicardium.

13. A non-transitory computer readable medium containing a medical image processing program for causing a computer to execute an operation to extract an endocardium of a left ventricle from 3D image data representing the left ventricle, the program causing the computer to carry out the steps of:

extracting a blood region in the left ventricle from the image data;

finding a convex hull from a plurality of sample points on a contour of the extracted blood region and identifying convex points forming the convex hull and concave points, which are sample points other than the convex points; and

deforming the contour of the blood region by moving at least a part of the concave points outward from the blood region by an amount determined based on a positional relationship among each concave point and the convex points located around the concave point and determining a deformed contour of the blood region to be the endocardium.

14. The non-transitory computer readable medium as claimed in claim 13, wherein the step of identifying the convex and concave points comprises identifying the convex points forming the convex hull and the concave points, which are the sample points other than the convex points, by finding the convex hull from the sample points on the contour of the extracted blood region in each of pieces of 2D image data representing cross sections perpendicular to an axis passing through a base and an apex of a heart set in the left ventricle;

and

the step of determining the endocardium comprises obtaining, in each of the pieces of 2D image data, a deformed contour of the blood region deformed by moving at least a part of the concave points outward from the blood region based on a positional relationship among each concave point and the convex points located on both sides of the concave point, and determining the endocardium based on the deformed contour.