Methods and systems for presenting an inhalation experience

• US 8,694,330 B2
• Filed: 04/01/2009
• Issued: 04/08/2014
• Est. Priority Date: 12/30/2008
• Status: Active Grant

• Current Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Hyde, Roderick A., Langer, Robert, Leuthardt, Eric C., Lord, Robert W., Sweeney, Elizabeth A., Tegreene, Clarence T., Wood, Lowell L. Jr.
• Primary Examiner(s): NGUYEN, HIEP VAN
• Application Number:
  US12/384,203
• Publication Number:
  US 20100163037A1
• Time in Patent Office: 1,833 Days
• Field of Search: 705/1
• US Class Current: 705/2
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/02 Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0065 Inhalators with dosage or measuring devices A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 15/02 with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2021/0016 : by the smell sense
• CPC Class Codes: A61M 2205/3553 : remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3569 : sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3584 : using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/3592 : using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/50 : with microprocessors or computers
• CPC Class Codes: A61M 2205/581 : by audible feedback
• CPC Class Codes: A61M 2205/582 : by tactile feedback
• CPC Class Codes: A61M 2205/583 : by visual feedback
• CPC Class Codes: A61M 2205/588 : by olfactory feedback, i.e. smell
• CPC Class Codes: A61M 2209/088 : on the body
• CPC Class Codes: A61M 2230/201 : Glucose concentration
• CPC Class Codes: A61M 2230/205 : partial oxygen pressure (P-O2)
• CPC Class Codes: A63F 2300/65 : for computing the condition of a game character
• CPC Class Codes: A63F 2300/6692 : using special effects, generally involving post-processing, e.g. blooming
• CPC Class Codes: G16H 20/13 : delivered from dispensers

Abstract

Methods, computer program products, and systems are described that include measuring at least one effect of an inhalation device-dispensed bioactive agent and artificial sensory experience on an individual and modifying at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on the at least one effect.

Claims

1. A system, comprising:

an effect measurer module configured to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience;

a behavior measurer module configured to observe at least one behavior of the individual engaged with the artificial sensory experience;

a behavior data comparer module configured to compare the observed at least one behavior with at least some expected behavior data associated with the artificial sensory experience; and

a modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior, wherein at least one of the effect measurer module, the behavior measurer module, the behavior data comparer module, or the modifier module is at least partially implemented using one or more processing devices.

2. The system of claim 1, wherein the effect measurer module configured to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience comprises:

an empirical data comparer module.

3. The system of claim 1, wherein the effect measurer module configured to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience comprises:

an effect measurer module configured to utilize medical imaging, the medical imaging including at least one of magnetic resonance imaging or computed tomography, to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience.

4. The system of claim 1, wherein the effect measurer module configured to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience comprises:

a laboratory test utilizer module.

5. The system of claim 1, wherein the effect measurer module configured to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience comprises:

a self assessment measurer module.

6. The system of claim 1, wherein the effect measurer module configured to measure at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience comprises:

a computerized assessment measurer module.

7. The system of claim 6, wherein the computerized assessment measurer module comprises:

a score measurer.

8. The system of claim 1, wherein the behavior measurer module configured to observe at least one behavior of the individual engaged with the artificial sensory experience comprises:

a behavior measurer module configured to observe a rate of respiration of the individual engaged with the artificial sensory experience.

9. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a mobile device modifier module configured to, at least partially responsive to the measuring the at least one effect and the comparing the observed at least one behavior, modify an artificial sensory experience implemented on at least one mobile device associated with the individual, including at least;

modifying, at least partially responsive to the measuring the at least one effect and the comparing the observed at least one behavior, at least one visual effect of the mobile device while at least some medication is bioavailable to the individual.

10. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

an access modifier module.

11. The system of claim 10, wherein the access modifier module comprises:

a restricter module.

12. The system of claim 10, wherein the access modifier module comprises:

a granter module.

13. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a visual object modifier module.

14. The system of claim 13, wherein the visual object modifier module comprises:

a color scheme modifier module.

15. The system of claim 13, wherein the visual object modifier module comprises:

a text modifier module.

16. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a sound alterer module.

17. The system of claim 16, wherein the sound alterer module comprises:

a music alterer module.

18. The system of claim 16, wherein the sound alterer module comprises:

an ambient noise alterer module.

19. The system of claim 16, wherein the sound alterer module comprises:

a voice alterer module.

20. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a dosage modifier module.

21. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a combination modifier module.

22. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a delivery modifier module.

23. The system of claim 22, wherein the delivery modifier module comprises:

a bioactive agent deliverer module.

24. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

an efficacy modifier module.

25. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a side effect reduction modifier module.

26. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

an adder module.

27. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a deleter module.

28. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a sensate experience modifier module.

29. The system of claim 28, wherein the sensate experience modifier module comprises:

a stimulus modifier module.

30. The system of claim 1, wherein the modifier module configured to modify at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on measuring the at least one effect and the comparing the observed at least one behavior comprises:

a mobile device modifier module.

31. The system of claim 1, further comprising:

a presenter module.

32. The system of claim 31, wherein the presenter module comprises:

an output device presenter module.

33. The system of claim 32, wherein the output device presenter module comprises:

a user interface presenter module.

34. The system of claim 32, wherein the output device presenter module comprises:

a mobile device presenter module.

35. The system of claim 31, wherein the presenter module comprises:

a third party presenter module.

36. The system of claim 35, wherein the third party presenter module comprises:

a health care provider presenter module.

37. The system of claim 35, wherein the third party presenter module comprises:

a selective presenter module.

38. A method, comprising:

measuring at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience;

observing at least one behavior of the individual engaged with the artificial sensory experience;

comparing the observed at least one behavior with at least some expected behavior data associated with the artificial sensory experience; and

modifying at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on the measuring at least one effect and the comparing the observed at least one behavior,

wherein at least one of the measuring, observing, comparing or modifying is at least partially implemented in hardware.

39. The method of claim 38, wherein measuring at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual engaged with the artificial sensory experience and observing at least one behavior of the individual engaged with the artificial sensory experience comprise:

measuring at least one effect of at least one of an inhalation device-dispensed anti-anxiety medication or a simulated flying experience on an individual being conditioned to overcome a flying phobia; and

observing at least one rate of respiration of the at least one individual responsive to a jet landing portion of the simulated flying experience.

40. The method of claim 39, wherein comparing the observed at least one behavior with at least some expected behavior data associated with the artificial sensory experience and modifying at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on the measuring at least one effect and the comparing the observed at least one behavior comprise:

comparing the observed at least one rate of respiration of the at least one individual responsive to the jet landing portion of the simulated flying experience with at least some average response data for a group of individuals; and

modifying at least one of the inhalation device-dispensed anti-anxiety medication or the simulated flying experience at least partially based on the measuring at least one effect and the comparing the observed at least one rate of respiration.

41. The method of claim 40, wherein modifying at least one of the inhalation device-dispensed anti-anxiety medication or the simulated flying experience at least partially based on the measuring at least one effect and the comparing the observed at least one rate of respiration comprises:

modifying the simulated flying experience visually, including at least adding window covers over the windows of a virtual plane of the simulated flying experience, at least partially based on the measuring at least one effect and the comparing the observed at least one rate of respiration.

42. A method, comprising:

measuring at least one effect of at least one of an inhalation device-dispensed bioactive agent or an artificial sensory experience on an individual;

modifying at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on the measuring at least one effect of at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience, the modifying the at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially triggering one or more of sight, hearing, touch or taste in the at least one individual,

wherein at least one of the measuring or modifying is at least partially implemented in hardware.