Two-stage reconstituting injector

• US 8,696,618 B2
• Filed: 08/13/2012
• Issued: 04/15/2014
• Est. Priority Date: 05/03/2006
• Status: Active Grant

• Current Assignee: Antares Pharma Incorporated
• Original Assignee: Antares Pharma Incorporated
• Inventors: Kramer, Thomas E., Sadowski, Peter L.
• Primary Examiner(s): FLICK, JASON E
• Application Number:
  US13/584,317
• Publication Number:
  US 20120302989A1
• Time in Patent Office: 610 Days
• Field of Search: 604/82
• US Class Current: 604/82
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/2474 with movable piercing means, e.g. ampoule remains fixed or steady
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/2466 by piercing without internal pressure increase A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.

Claims

1. An injector for injecting a medicament into a patient, comprising:

a container, the container defining a first chamber containing a fluid, and a second chamber;

an injection conduit in association with the container and configured for directing a fluid fired from the container into the patient, the injection conduit having a position that is fluidly incommunicated with the second chamber;

a transfer mechanism operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation;

a firing mechanism operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation, the firing mechanism including a needle guard that has a protective position disposed for covering a needle of the injection conduit, and a retracted position exposing the needle;

a cap covering the injection conduit, the needle, and the needle guard;

an energy source in powering association with the transfer and firing mechanisms to drive transfer and firing mechanisms in both the first and second stages; and

a transfer control that is manually operable to operate the transfer mechanism in the first stage of operation and to fluidly communicate the injection conduit with the second chamber in the first stage of operation,

wherein the needle guard is configured for causing the firing mechanism to fire the fluid when moved to the retracted position.

2. The injector of claim 1, further comprising an injection trigger mechanism operably associated with the firing mechanism to operate the firing mechanism in the second stage.

3. The injector of claim 1, wherein the transfer control is further manually operable to vent the second chamber.

4. The injector of claim 1, wherein the transfer control comprises a second cap associated with the container and disposed to cover the injection conduit prior to the first stage of operation, which cap is separable from the injection conduit and container after the first stage of operation.

5. The injector of claim 1, wherein the injection conduit comprises a communicating needle portion, the transfer control operable to relatively move the communicating needle portion with respect to the second chamber to pierce the container to fluidly communicate the second chamber with the communicating needle portion in the first stage of operation.