Debubbler

• US 8,696,626 B2
• Filed: 07/30/2008
• Issued: 04/15/2014
• Est. Priority Date: 07/30/2008
• Status: Active Grant

• Current Assignee: Claudia F.E. Kirsch
• Original Assignee: Claudia F.E. Kirsch
• Inventors: Kirsch, Claudia F. E.
• Primary Examiner(s): Lucchesi, Nicholas
• Assistant Examiner(s): Zhang, Jenna
• Application Number:
  US12/182,489
• Publication Number:
  US 20100030151A1
• Time in Patent Office: 2,085 Days
• Field of Search: 604/122, 604/123, 604/126, 604/128, 604/129, 961/93, 95/46, 422/48
• US Class Current: 604/126
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 5/36 with means for eliminating or preventing injection or infusion of air into body dialysis systems, blood oxygenators A61M1/14; haemofiltration equipment A61M1/34; automatic tube cut-off A61M39/281
• CPC Class Codes: A61M 5/385 using hydrophobic filters
• CPC Class Codes: B01D 19/0031 by filtration
• CPC Class Codes: B01D 19/0036 Flash degasification the other groups take precedence

Abstract

A device for removal of a gas from a liquid in a medical infusion line has a housing containing a plurality of hollow fiber membranes. Preferably liquid passes on the exterior of the membranes and gas bubbles in the liquid pass into the lumens of the hollow fiber membranes. This is for removal by a vacuum. The device can include its own vacuum chamber. When the device has its own vacuum chamber, it can include a warning system to alert a user to replace the device when the provided vacuum is no longer sufficient.

Claims

1. A device for removal of gas from a liquid being delivered to a patient through a medical fluid infusion line, the device comprising:

a) a housing having an internal surface, an internal degassing chamber in the housing, a vacuum chamber in the housing, an inlet port for receiving liquid from the medical fluid infusion line for flow into the internal degassing chamber, an outlet port for discharging the liquid from the degassing chamber, and a vent in communication with the degassing chamber for passing gas from the degassing chamber to the vacuum chamber;

b) a plurality of hollow fiber membranes in the internal degassing chamber for removing gas from the liquid, wherein removed gas is in gas flow communication with the vent; and

c) a mechanical source of vacuum in the housing containing the hollow fiber membranes, the mechanical source of vacuum being movably mounted in the vacuum chamber and entirely in the housing and in gas flow communication with the vent for withdrawing gas from the internal degassing chamber to the vacuum chamber so that the device is self-contained and adapted for use without connection to an external source of vacuum,

wherein the mechanical source of the vacuum comprises a piston having a length about equal to the distance between the inlet port and the outlet port, the piston being biased away from the vent by a spring.

2. The device of claim 1 wherein the vacuum at the vent is from about 25 ton to about 500 torr.

3. The device of claim 2 wherein the vacuum at the vent is from about 50 torr to about 125 torr.

4. The device of claim 1 comprising an indicator for indicating when the piston has moved to a warning position that the piston no longer provides an effective vacuum.

5. The device of claim 4 comprising an alert switch activatable by the piston for providing a perceptible alert that the piston no longer provides an effective vacuum, the alert switch being positioned that the alert switch is activated after the piston has moved to the warning position.

6. The device of claim 5 wherein the perceptible alert is selected from the group consisting of an audible beep, flashing lights, and an electric signal.

7. A method for removing gas from a liquid infused to an internal delivery site of an organism, the method comprising the steps of:

a) selecting the device of claim 4; and

b) introducing the liquid into the inlet port of the device; and

c) replacing or adjusting the device after the piston moves to the warning position.

8. The device of claim 1 comprising an alert switch activatable by the piston for providing a perceptible alert to replace or adjust the device.

9. A method for removing gas from a liquid infused to an internal delivery site of an organism, the method comprising the steps of:

a) selecting the device of claim 8;

b) introducing the liquid into the inlet port of the device; and

c) replacing the device when the perceptible alert is perceived.

10. A method for removing gas from a liquid infused to an internal delivery site of an organism, the method comprising the steps of:

a) selecting the device of claim 1; and

b) introducing the liquid into the inlet port of the device.

11. The device of claim 1 wherein each hollow fiber membrane has an external wall and an internal lumen and are substantially impervious to the liquid and are pervious to gas in the liquid, wherein the external wall of each hollow fiber membrane is in liquid flow communication with the inlet port but not in gas flow communication with the vent, and

wherein the internal lumens of each hollow fiber membrane is in gas flow communication with the vent but not in liquid flow communication with the inlet port, so that gas in the liquid can pass through the external wall of each hollow fiber membrane without the liquid and be vented from the hollow fiber membranes through the vent.

12. The device of claim 1 wherein the housing has a vacuum connection in communication with the degassing chamber, wherein the vacuum connection can be attached to an external source of vacuum so the device can be used both with an external source of vacuum and without the external source of vacuum.

13. The device of claim 12 comprising a cap for optionally closing the vacuum connection.

14. A method for removing gas from a liquid being infused to an internal delivery site of an organism, the method comprising the steps of:

a) selecting the device of claim 13, wherein if the cap is on the vacuum connection the cap is removed from the vacuum connection;

b) connecting the vacuum connection to a vacuum source; and

c) introducing the liquid into the inlet port of the device, wherein gas is removed from the liquid and sucked through the vacuum connection toward the vacuum source.

15. A device suitable for removal of gas from a liquid being delivered to a patient through a medical fluid infusion line, the device comprising:

a) a housing having an internal surface, an internal degassing chamber in the housing, a vacuum chamber in the housing, an inlet port for receiving liquid from the medical fluid infusion line for flow into the internal degassing chamber, an outlet port for discharging the liquid from the degassing chamber, a vent in communication with the degassing chamber for passing gas from the degassing chamber to the vacuum chamber, and a vacuum connection in communication with the degassing chamber;

b) a plurality of hollow fiber membranes in the internal degassing chamber for removing gas from the liquid, wherein removed gas is in gas flow communication with the vent and the vacuum connection; and

c) a mechanical source of vacuum completely in the housing and comprising a piston movably mounted in the vacuum chamber and a spring biasing the piston away from the vent, the spring and piston being in gas flow communication with the vent for withdrawing gas from the internal degassing chamber so that the device is self-contained and adapted for use without connection to an external source of vacuum;

d) wherein the vacuum connection can be attached to the external source of vacuum so the device can be used both with the external source of vacuum and without the external source of vacuum; and

e) a cap for optionally closing the vacuum connection.