Braid-ball embolic devices

• US 8,696,701 B2
• Filed: 09/28/2012
• Issued: 04/15/2014
• Est. Priority Date: 04/21/2008
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Becking, Frank P., Rosqueta, Arturo S.
• Primary Examiner(s): Erezo, Darwin
• Assistant Examiner(s): Yabut, Diane
• Application Number:
  US13/631,470
• Publication Number:
  US 20130085522A1
• Time in Patent Office: 564 Days
• Field of Search: 606/194, 606/200, 606/213, 623/1.11
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00862 elastic or resilient for sutures A61B2017/0618
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2018/00416 Treatment of aneurisms
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: Y10T 156/1051 by folding

Abstract

Embolic implants, delivery systems and methods of manufacture and delivery are provided. The devices can be used for aneurysm treatment and/or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

Claims

1. An embolic device that is adapted to occlude an aneurysm, comprising:

a braid body having a distal end region and a proximal end region, the braid body having a fold in the distal end region that forms an inner layer and an outer layer,

wherein the outer layer is biased to transition from a compressed shape that is adapted for delivery through a catheter, to an expanded shape, the expanded shape of the outer layer converging towards the distal end region such that it is dome-shaped and converging towards the proximal end region of the braid body such that it is flared,

wherein the inner layer is biased to transition from a compressed shape that is adapted for delivery through a catheter, to an expanded shape that defines an open, rounded volume, and

wherein a distance between the inner layer and the outer layer is substantially constant between the distal end region and the proximal end region of the inner layer, the inner and outer layers being coupled together at a hub in the proximal end region of the braid body, the hub having an open access port.

2. The embolic device of claim 1, further comprising a band coupled with the braid body at the hub.

3. The embolic device of claim 1, wherein a plurality of filaments of the braid are coupled together at the hub with a weld.

4. The embolic device of claim 1, wherein a radiopaque marker is coupled with the distal end region of the braid body.

5. The embolic device of claim 1, wherein a plurality of filaments of the braid body are coupled together at the hub with a weld.

6. The embolic device of claim 1, wherein the expanded shape of the inner layer substantially follows the expanded shape of the outer layer.

7. The embolic device of claim 1, wherein when expanded, the inner and outer layers each form substantially spherical shapes.

8. An embolic device adapted to occlude an aneurysm, comprising:

a braid body having a distal end region and a proximal end region, the braid body having a fold in the distal end region that forms an inner layer and an outer layer,

wherein a distance between the inner layer and the outer layer is substantially constant between the distal end region and the proximal end region of the inner layer,

wherein the outer layer is biased to transition from a compressed shape that is adapted for delivery through a catheter, to an expanded shape, the expanded shape of the outer layer converging towards the distal end region and the proximal end region of the braid body, and

wherein the inner layer is biased to transition from a compressed shape that is adapted for delivery through the catheter, to an expanded shape that is located within the outer layer.

9. The embolic device of claim 8, further comprising a fold in the distal end region coupled to the inner and outer layers and a filament tie interposed between the inner and outer layers adjacent the fold.

10. The embolic device of claim 8, wherein the expanded shape of the inner layer substantially follows the expanded shape of the outer layer.

11. The embolic device of claim 8, wherein the inner and outer layers are coupled together in the proximal end region of the braid body.

12. The embolic device of claim 8, wherein a hub is present in the proximal end region of the braid body.

13. The embolic device of claim 12, wherein the inner layer terminates distal to the hub.

14. The embolic device of claim 12, further comprising a band coupled with the braid body at the hub.

15. The embolic device of claim 12, wherein a plurality of filaments of the braid body are coupled together at the hub with a weld.

16. The embolic device of claim 8, wherein the proximal end region includes an access port.

17. The embolic device of claim 8, wherein a distal side of the outer layer is dome-shaped in the expanded shape.

18. The embolic device of claim 8, wherein a proximal side of the outer layer is flared in the expanded shape.

19. The embolic device of claim 8, wherein a radiopaque marker is coupled with the distal end region of the braid body.

20. The embolic device of claim 8, wherein a distal-most end of the braid body is open.

21. The embolic device of claim 8, wherein a distal-most end of the braid body is tied closed.

22. The embolic device of claim 8, wherein the inner layer defines an open, rounded volume in the expanded shape.

23. The embolic device of claim 8, wherein when expanded, the inner and outer layers each form substantially spherical shapes.

24. An embolic device adapted to occlude an aneurysm, comprising:

a braid body having a first end region and a second end region opposite the first end region, the braid body having a fold in the first end region that forms an inner layer and an outer layer,

wherein the outer layer is biased to transition from a compressed shape that is adapted for delivery through a catheter, to an expanded shape, the expanded shape of the outer layer converging towards the first end region and the second end region of the braid body, and

wherein the inner layer comprises a substantially cylindrical portion spaced at a substantially constant distance from the outer layer, the inner layer being biased to transition from a compressed shape that is adapted for delivery through the catheter, to an expanded shape that is located within the outer layer.

25. The embolic device of claim 24, wherein the inner and outer layers are coupled together in the second end region of the braid body.

26. The embolic device of claim 24, wherein a hub is present in the second end region of the braid body.

27. The embolic device of claim 24, wherein when expanded, the inner and outer layers each form substantially hemi-spherical shapes.