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Methods related to TIM 3, a Th1-specific cell surface molecule, for activating antigen presenting cells

  • US 8,697,069 B2
  • Filed: 12/20/2011
  • Issued: 04/15/2014
  • Est. Priority Date: 01/30/2002
  • Status: Active Grant
First Claim
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1. A method for promoting antigen presenting cell (APC) activation, comprising contacting a T cell with a T cell Immunoglobulin domain and Mucin domain (TIM-3)-binding molecule;

  • and contacting an APC with the T cell to activate the APC, wherein the TIM-3-binding molecule is an antibody specific for TIM-3 or an antigen-binding fragment of an antibody specific for TIM-3.

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