Sensor for detection of carbohydrate
First Claim
1. A sensor for the detection or measurement of carbohydrate analyte in fluid, the sensor comprising components of a competitive binding assay the readout of which is a detectable or measurable optical signal retained by a material that permits diffusion of analyte but not the assay components, the assay components comprising:
- a mammalian lectin; and
an analyte analogue capable of competing with analyte for binding to the lectin;
wherein the lectin is mannose binding lectin.
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Accused Products
Abstract
A sensor for the detection or measurement of carbohydrate analyte (such as glucose) in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal (such as FRET assay) retained by a material that permits diffusion of analyte but not the assay components, the assay components comprising: an animal lectin; and an analyte analogue capable of competing with analyte for binding to the lectin.
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Citations
27 Claims
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1. A sensor for the detection or measurement of carbohydrate analyte in fluid, the sensor comprising components of a competitive binding assay the readout of which is a detectable or measurable optical signal retained by a material that permits diffusion of analyte but not the assay components, the assay components comprising:
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a mammalian lectin; and an analyte analogue capable of competing with analyte for binding to the lectin; wherein the lectin is mannose binding lectin. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A sensor for the detection or measurement of carbohydrate analyte in fluid, the sensor comprising components of a competitive binding assay the readout of which is a detectable or measurable optical signal retained by a material that permits diffusion of analyte but not the assay components, the assay components comprising:
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an animal lectin; and an analyte analogue capable of competing with analyte for binding to the lectin; wherein the lectin is in multimeric form, and wherein the lectin is mannose binding lectin in trimeric and/or tetrameric form.
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Specification