System and method for computer aided septal defect diagnosis and surgery framework

• US 8,700,126 B2
• Filed: 01/11/2007
• Issued: 04/15/2014
• Est. Priority Date: 01/11/2007
• Status: Active Grant

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Li, Shou, Gill, Sukhdeep, Mahesh, Prakash, Roeder, Dave
• Primary Examiner(s): Chen, Tse
• Assistant Examiner(s): REMALY, MARK DONALD
• Application Number:
  US11/622,272
• Publication Number:
  US 20080171933A1
• Time in Patent Office: 2,651 Days
• Field of Search: 600/407, 600/410, 600/413, 600/419, 600/425, 600/426, 600/428
• US Class Current: 600/413
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/7289 Retrospective gating, i.e. associating measured signals or images with a physiological event after the actual measurement or image acquisition, e.g. by simultaneously recording an additional physiological signal during the measurement or image acquisition

Abstract

Certain embodiments of the present invention provide systems and methods for detecting septal defects. In an embodiment, the method may include acquiring gated MRI data and heart atlas data. A registration of the gated MRI data and the heart atlas data may be performed as well as a flow-balance measurement. An atrial septal detection and ventricular septal detection may be performed, as well as a septal measurement. A diagnostic report may be generated detailing the location and properties of the septal defects. A physician may utilize the diagnostic report for surgery planning. After surgery, the diagnostic report may be compared with a post-surgery diagnostic report to determine the success of the surgery.

Claims

1. A method for detecting a septal defect of a patient, the method comprising:

using a computer unit to perform at least the following;

acquiring gated MRI data of actual patient anatomy and pre-computed heart atlas data;

registering the gated MRI data with the pre-computed heart atlas data, wherein said registering indicates differences between the gated MRI data and the pre-computed heart atlas data, wherein said registering includes registering a first set of 3D volume images of the gated MRI data and the pre-computed heart atlas data for the voxels of the gated MRI data;

performing a flow-balance measurement comprising identifying two markers used to measure the amount of blood pumped into and out of a heart of the patient;

performing atrial septal detection and ventricular septal detection;

performing septal measurement; and

reporting output information in a diagnostic report.

2. The method of claim 1, further including registering a second set of 3D volume images of the gated MRI data and the pre-computed heart atlas data for heart wall voxels of the gated MRI data.

3. A method for detecting a septal defect of a patient, the method comprising:

using a computer unit to perform at least the following;

acquiring gated MRI data of actual patient anatomy and pre-computed heart atlas data;

registering the gated MRI data with the pre-computed heart atlas data, wherein said registering indicates differences between the gated MRI data and the pre-computed heart atlas data;

performing a flow-balance measurement comprising identifying two markers used to measure the amount of blood pumped into and out of a heart of the patient;

performing atrial septal detection and ventricular septal detection;

performing septal measurement; and

reporting output information in a diagnostic report, wherein the diagnostic report includes the following properties for each defect;

maximal size, minimal size, the location of the defect, whether the defect is an atrial septal defect or a ventricular septal defect.

4. A method for detecting a septal defect of a patient, the method comprising:

using a computer unit to perform at least the following;

acquiring gated MRI data of actual patient anatomy and pre-computed heart atlas data;

registering the gated MRI data with the pre-computed heart atlas data, wherein said registering indicates differences between the gated MRI data and the pre-computed heart atlas data;

performing a flow-balance measurement comprising identifying two markers used to measure the amount of blood pumped into and out of a heart of the patient;

performing atrial septal detection and ventricular septal detection;

performing septal measurement; and

reporting output information in a diagnostic report, wherein the diagnostic report includes the ability to visualize the defects.

5. A method for detecting a septal defect of a patient, the method comprising:

using a computer unit to perform at least the following;

acquiring gated MRI data of actual patient anatomy and pre-computed heart atlas data;

registering the gated MRI data with the pre-computed heart atlas data, wherein said registering indicates differences between the gated MRI data and the pre-computed heart atlas data;

performing a flow-balance measurement comprising identifying two markers used to measure the amount of blood pumped into and out of a heart of the patient;

performing atrial septal detection and ventricular septal detection;

performing septal measurement; and

reporting output information in a diagnostic report, further including;

acquiring post-surgery gated MRI data of the actual patient anatomy and the pre-computed heart atlas data;

registering the post-surgery gated MRI data with the pre-computed heart atlas data;

performing a post-surgery flow-balance measurement;

performing post-surgery atrial septal detection and post-surgery ventricular septal detection;

performing post-surgery septal measurement; and

reporting output information in a post-surgery diagnostic report.

6. The method of claim 5, wherein said registering the post-surgery gated MRI data with the heart atlas data includes registering a first set of 3D volume images of the post-surgery gated MRI data and the heart atlas data for the voxels of the post-surgery gated MRI data.

7. The method of claim 6, further including registering a second set of 3D volume images of the post-surgery gated MRI data and the heart atlas data for heart wall voxels of the post-surgery gated MRI data.

8. The method of claim 7, further including comparing the diagnostic report with the post-surgery diagnostic report.

9. A non-transitory computer-readable storage medium storing a set of instructions for a computer, the stored set of instructions comprising:

an acquisition routine for acquiring gated MRI data of actual patient anatomy and pre-computed heart atlas data;

a registration routine for registering the gated MRI data and the pre-computed heart atlas data;

a flow-balance routine for performing a flow-balance measurement that identifies two markers the measure blood pumped into and out of a heart of a patient;

a detection routine for performing atrial septal detection and ventricular septal detection;

a septal measurement routine for performing septal measurement; and

a diagnostic routine for reporting output information in a diagnostic report, wherein the registration routine includes a routine a first set of 3D volume images of the gated MRI data and the heart atlas data for the voxels of the gated MRI data.

10. The non-transitory computer readable medium of claim 9, wherein the registration routine includes a routine for registering a second set of 3D volume images of the gated MRI data and the heart atlas data for heart wall voxels of the gated MRI data.

11. A non-transitory computer-readable storage medium storing a set of instructions for a computer, the stored set of instructions comprising:

an acquisition routine for acquiring gated MRI data of actual patient anatomy and pre-computed heart atlas data;

a registration routine for registering the gated MRI data and the pre-computed heart atlas data;

a flow-balance routine for performing a flow-balance measurement that identifies two markers the measure blood pumped into and out of a heart of a patient;

a detection routine for performing atrial septal detection and ventricular septal detection;

a septal measurement routine for performing septal measurement; and

a diagnostic routine for reporting output information in a diagnostic report, further including;

a post-surgery acquisition routine for acquiring gated MRI data of the actual patient anatomy and the pre-computed heart atlas data;

a post-surgery registration routine for registering the gated MRI data and the heart atlas data;

a post-surgery flow-balance routine for performing a flow-balance measurement;

a post-surgery detection routine for performing atrial septal detection and ventricular septal detection;

a post-surgery septal measurement routine for performing septal measurement; and

a post-surgery diagnostic routine for reporting output information in a post-surgery diagnostic report.

12. The non-transitory computer readable medium of claim 11, wherein the post-surgery registration routine includes a routine for registering a first set of 3D volume images of the post-surgery gated MRI data and the heart atlas data for the voxels of the post-surgery gated MRI data and for registering a second set of 3D volume images of the post-surgery gated MRI data and the heart atlas data for heart wall voxels of the post-surgery gated MRI data.

13. The non-transitory computer readable medium of claim 11, further including a comparison routine for comparing the diagnostic report with the post-surgery diagnostic report.