Thrombus retrieval device

• US 8,702,724 B2
• Filed: 12/21/2009
• Issued: 04/22/2014
• Est. Priority Date: 05/18/2009
• Status: Active Grant

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Inventors: Olsen, Kian, Jensen, Anders Ginge, Christiansen, Frank, Skdt, Carsten, Elgrd, Per
• Primary Examiner(s): Holwerda, Kathleen
• Assistant Examiner(s): TANNER, JOCELIN C
• Application Number:
  US12/643,204
• Publication Number:
  US 20100292726A1
• Time in Patent Office: 1,583 Days
• Field of Search: 606/200, 606/191, 606/198, 606/159, 606/194, 606/108, 606/213, 606/128, 606/127, 606/46, 606/47, 606/170, 606/171, 606/167, 606110-115, 606/48, 606/45, 623/1.11, 604104-109, 604/262, 604/267, 600562-572, 600/206, 600/106, 600/184, 600/104, 600/107, 600/114, 600/373, 600/374, 600/385, 600/393, 607/113, 607125-128, 607/122
• US Class Current: 606/127
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/32056 Surgical snare instruments for removing or smashing calculi A61B2017/2212; tonsillotomes A61B17/26
• CPC Class Codes: A61B 2017/00867 shape memory effect

Abstract

A thrombus retrieval device has one or more thrombus engaging elements that are movable between a retracted configuration in which they are stowed within the device and a deployed configuration in which they project from the device to snare an adjacent thrombus for removal from a blood vessel.

Claims

1. A device for the retrieval of a thrombus from a blood vessel, the device comprising:

a delivery tube with a plurality of side holes oriented radially, the delivery tube being insertable into a blood vessel containing a thrombus; and

one or more thrombus engaging elements for each side hole, each thrombus engaging element comprising a wire and being movable radially of the delivery tube between a retracted configuration in which it is retained within the delivery tube and a deployed configuration in which it projects from the delivery tube through the side hole, wherein each wire has a free end being movable radially of the delivery tube between the retracted and deployed configurations and is configured for piercing a thrombus, wherein a portion of each wire has a semi-circular shape in a radial plane of the delivery tube after deployment and extends from the side hole to the free end in the same circumferential direction as each other one of the thrombus engaging elements.

2. The device of claim 1, wherein the free end is movable along a curved path in said radial plane between the retracted and deployed configurations.

3. The device of claim 1, wherein each thrombus engaging element is arranged so that movement of its proximal end along the delivery tube causes its distal end to move radially.

4. The device of claim 1, wherein a portion of the wire has a circular shape after deployment.

5. The device of claim 1, wherein one or more of the one or more thrombus engaging elements are made of a memory material.

6. The device of claim 5, wherein one or more of the one or more thrombus engaging elements are made of NiTi.

7. The device of claim 1, further comprising one or more radiopaque markers arranged to allow determination of the position of the plurality of side holes.

8. The device of claim 1, wherein at least a portion of one or more of the one or more thrombus engaging elements is textured.

9. The device of claim 1, wherein at least a portion of one or more of the one or more thrombus engaging elements has a cross sectional profile comprising one or more flat edges.

10. The device of claim 1, further comprising two or more thrombus engaging elements and two or more side holes, the side holes being arranged in a line parallel to a longitudinal axis of the device.

11. A device for the retrieval of a thrombus from a blood vessel, the device comprising:

a delivery tube with at least two side holes oriented radially, the delivery tube being insertable into a blood vessel containing a thrombus; and

one or more thrombus engaging elements for each side hole, each thrombus engaging element comprising a wire configured to pierce a thrombus and being movable radially of the delivery tube between a retracted configuration in which it is retained within the delivery tube and a deployed configuration in which it projects from the delivery tube through the side hole, wherein each thrombus engaging element is configured to curl in a radial plane of the delivery tube after deployment through the side hole, wherein all of the thrombus engaging elements curl in a clockwise direction or all of the thrombus engaging elements curl in a counterclockwise direction.

12. The device of claim 11, further comprising a pushing member for transmitting a pushing force to the one or more thrombus engaging elements, wherein the cross-sectional area of the pushing member is greater than that of the one or more thrombus engaging elements, the pushing member having a stop surface cooperating with a complementary stop surface in the delivery tube, the stop surfaces defining the deployed configuration of the one or more thrombus engaging elements by abutting each other.

13. A device for the retrieval of a thrombus from a blood vessel, the device comprising:

a delivery tube with at least two side holes oriented radially, the delivery tube being insertable into a blood vessel containing a thrombus; and

one or more thrombus engaging elements for each side hole, each thrombus engaging element being movable radially of the delivery tube between a retracted configuration in which it is retained within the delivery tube and a deployed configuration configured for piercing thrombi with a free end, in which it projects in a radial plane and extends from the delivery tube through the side hole to the free end in the same circumferential direction as each other one of the thrombus engaging elements, the device further comprising a positioning apparatus configured in use operable to push the delivery tube against a wall of the vessel, wherein the delivery tube further comprises a positioning hole and the positioning apparatus comprises a deployable positioning wire movable between a retracted configuration in which it is retained in the delivery tube and a positioning configuration in which it projects from the delivery tube through the positioning hole so as to push the delivery tube against a wall of the vessel.

14. The device of claim 13, wherein the deployable positioning wire is configured to curl after deployment through the positioning hole.

15. A device for the retrieval of a thrombus from a blood vessel, the device comprising:

a delivery tube with a plurality of side holes oriented radially, the delivery tube being insertable into a blood vessel containing a thrombus; and

one or more thrombus engaging elements for each side hole, each thrombus engaging element being movable radially of the delivery tube between a retracted configuration in which it is retained within the delivery tube and a deployed configuration in which it projects with a free end from the delivery tube through the side hole and curls in a radial plane from the side hole to the free end in the same circumferential direction as each other one of the thrombus engaging elements, wherein the one or more thrombus engaging elements have cross-sections with one or more flat sides arranged so that, when the device is in the deployed configuration and is being retracted from the vessel in a direction transverse to a direction in which each thrombus engaging element projects, contact between the one or more flat sides and a wall of the vessel acts to push the contacted thrombus engaging element away from the vessel wall.

16. A device for the retrieval of a thrombus from a blood vessel, the device comprising:

a delivery tube with at least two side holes oriented radially, the delivery tube being insertable into a blood vessel containing a thrombus; and

one or more thrombus engaging elements for each side hole, each thrombus engaging element comprising a wire with a free distal end and being movable radially of the delivery tube between a retracted configuration in which it is retained within the delivery tube and a deployed configuration in which the free distal end projects from the delivery tube through the side hole, wherein the one or more thrombus engaging elements are curled with a curvature that, during movement into the deployed configuration, causes the free distal end to enter into the one or more holes in the delivery tube, leaving only intermediate portions of the one or more thrombus engaging elements project from the one or more side holes wherein all of the thrombus engaging elements curl in a clockwise direction or all of the thrombus engaging elements curl in a counterclockwise direction from the side holes to the free distal ends.