×

Low cost electrochemical disposable sensor for measuring glycated hemoglobin

  • US 8,702,931 B2
  • Filed: 04/18/2012
  • Issued: 04/22/2014
  • Est. Priority Date: 04/18/2011
  • Status: Expired due to Fees
First Claim
Patent Images

1. A sensor for measuring percentage glycated hemoglobin (GHb) and total hemoglobin (Hb), said sensor comprising:

  • a salts-and-surfactant-embedded membrane to receive a blood sample, and for lysing erythrocytes in said blood cell sample to release hemoglobin molecules,said salts-and-surfactant-embedded membrane to allow said hemoglobin molecules and plasma to pass through as a filtrate, wherein said blood sample contains erythrocytes, white blood cells (WBCs), and platelets;

    a first working electrode to measure concentration of glycated hemoglobin (GHb) contained in said filtrate;

    a second working electrode to measure concentration of total hemoglobin (Hb) contained in said filtrate;

    a reference electrode to operate as a reference with respect to which measurements from said first working electrode and said second working electrodes are made; and

    a counter electrode for providing charge balance,wherein said salts-and-surfactant-embedded membrane has pores of small enough magnitude to retain any unlysed erythrocytes, said WBCs and said platelets, such that said filtrate passed through contains only said hemoglobin molecules and plasma.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×