Medical devices for releasing therapeutic agent and methods of making the same
First Claim
1. A method for making an implantable medical device for releasing therapeutic agent, comprising:
- providing a medical device body;
positioning a plurality of reservoir-defining structures on a surface of the body to form at least one reservoir defined by the reservoir-defining structures;
loading therapeutic agent into the reservoir; and
moving a portion of at least one of the plurality of reservoir-defining structures from a first position to a second position so as to cover the reservoir almost completely such that an opening exists for the reservoir so that the therapeutic agent is released when the medical device is implanted,wherein the portion of the at least one of the plurality of reservoir-defining structures is moved after the therapeutic agent is loaded.
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Accused Products
Abstract
An implantable medical device for releasing therapeutic agent having a medical device body and a plurality of reservoir-defining structures disposed on a surface of the body. A reservoir can be defined by the reservoir-defining structures and therapeutic agent may be located in the reservoir. A cover may extend over the reservoir so that the therapeutic agent is released from the reservoir when the medical device implanted. Methods for making the medical device may also include providing a medical device body, positioning a plurality of reservoir-defining structures on a surface of the body to form a reservoir, loading therapeutic agent into the reservoir, and covering the reservoir so that the therapeutic agent may release when the medical device is implanted. Alternatively, the reservoir may be covered with a cover and an opening formed in the cover so that the therapeutic agent may release when the medical device is implanted.
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Citations
23 Claims
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1. A method for making an implantable medical device for releasing therapeutic agent, comprising:
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providing a medical device body; positioning a plurality of reservoir-defining structures on a surface of the body to form at least one reservoir defined by the reservoir-defining structures; loading therapeutic agent into the reservoir; and moving a portion of at least one of the plurality of reservoir-defining structures from a first position to a second position so as to cover the reservoir almost completely such that an opening exists for the reservoir so that the therapeutic agent is released when the medical device is implanted, wherein the portion of the at least one of the plurality of reservoir-defining structures is moved after the therapeutic agent is loaded. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method for making an implantable medical device for releasing therapeutic agent, comprising:
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providing a medical device body; positioning a plurality of reservoir-defining structures on a surface of the body to form at least one reservoir defined by the reservoir-defining structures; loading therapeutic agent into the reservoir; covering the reservoir with a cover; and forming a hole in the cover ex vivo so that the therapeutic agent releases through the opening when the medical device is implanted. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification