×

Inhibition of neovascularization by cerium oxide nanoparticles

  • US 8,703,200 B2
  • Filed: 04/24/2009
  • Issued: 04/22/2014
  • Est. Priority Date: 04/29/2005
  • Status: Active Grant
First Claim
Patent Images

1. A method of inhibiting, reducing and/or reversing neovascularization associated with a pathological ocular condition in a mammalian subject, the method comprising the steps of:

  • administering a therapeutically effective amount of a pharmaceutical composition to a mammalian subject exhibiting neovascularization associated with a pathological ocular condition, the pharmaceutical composition comprising cerium oxide nanoparticles and a pharmaceutically acceptable carrier; and

    reducing at least one of (a) at least one vascular anomaly, (b) the number of illicit neovessels, (c) the rate of retinal neovascularization, and (d) the rate of proliferation of neovascular tissue in the eye of the mammalian subject upon administration of the cerium oxide nanoparticles present in the pharmaceutical composition.

View all claims
  • 3 Assignments
Timeline View
Assignment View
    ×
    ×