Treatment related quantitative decision engine

• US 8,706,521 B2
• Filed: 07/15/2011
• Issued: 04/22/2014
• Est. Priority Date: 07/16/2010
• Status: Active Grant

• Current Assignee: Navya Network Inc.
• Original Assignee: Navya Network Inc.
• Inventors: Ramarajan, Naresh, Srivastava, Gitika
• Primary Examiner(s): Pauls, John
• Assistant Examiner(s): TIEDEMAN, JASON S
• Application Number:
  US13/183,757
• Publication Number:
  US 20120016690A1
• Time in Patent Office: 1,012 Days
• Field of Search: None
• US Class Current: 705/2
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: G16H 70/20 relating to practices or guidelines
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

A system and method generate a report to help decide among a plurality of treatment options for a medical condition. The system and method receive patient information and generate a plurality of potential treatment options for the medical condition. The system and method also receive the patient'"'"'s preference(s) for potential treatment outcomes of the treatment options, used to produce a preference value. The system and method also analyze indexed study data relating to the plurality of treatment options to produce, based on the analysis, a study score for each of the treatment options. For each treatment option, the system and method produce a treatment score based on at least the preference value and the study score, thus permitting generation of a report listing the treatment options and a) the treatment scores or b) the information derived from the treatment scores.

Claims

1. A method, for use with at least one processor on at least one computer, of generating a report to help decide among a plurality of treatment options for a patient with a given treatable medical condition, the method comprising:

receiving patient information related to the patient and the medical condition;

querying a treatment option database to generate a plurality of potential treatment options for the medical condition;

receiving preference information indicative of the patient'"'"'s preference for potential treatment outcomes of the treatment options to produce a preference value;

analyzing indexed study data relating to the plurality of treatment options by at least grading evidence within the indexed study data, wherein the indexed study data is derived from scientific studies, each of which evaluates an effect of a different treatment option on different trial subjects who have a similar medical condition as the patient;

producing a study score for each of the treatment options based on the analysis of the indexed data;

determining, for each distinct treatment option, a distinct treatment score as a function of at least the preference value and the study score corresponding to the distinct treatment option;

generating a report listing the treatment options and a) the treatment scores or b) information derived from the treatment scores.

2. The method as defined by claim 1 wherein the information derived from the treatment scores is a ranking of the treatment options as a function of the treatment scores for the treatment options.

3. The method as defined by claim 2, further comprising

determining that a difference between a highest treatment score and a next highest treatment score is larger than a threshold,

determining that no single value used to compute the highest treatment score is greater than the next highest treatment score or the value used to compute the next highest treatment score, and

selecting a recommended treatment option with the highest treatment score.

4. The method as defined by claim 2, further comprising

choosing two treatment options with the highest treatment scores;

determining if a difference between the two highest treatment scores falls below a pre-defined threshold, and if so, recalculating the treatment scores without using the preference value.

5. The method as define by claim 1, further comprising:

comparing the patient information with characteristics of trial subjects tested in at least one scientific study represented by the indexed study data to determine the applicability of at least one study to the patient, represented by an applicability value; and

recalculating, for each treatment option, the treatment score as a function of the preference value, study score, and applicability value.

6. The method as defined by claim 1 further comprising:

receiving treatment recommendations from a plurality of experts, the treatment recommendations relating to the plurality of treatment options;

converting, at least in part in a computer process, the treatment recommendations into an expert score for each treatment option; and

for each treatment option, recalculating the treatment score as a function of the preference value, study score, and expert score.

7. The method as define by claim 6, further comprising applying an expert weight to the expert score.

8. The method as defined by claim 7, wherein the expert weight is calculated using at least one of a ranking of the expert'"'"'s academic institution, a ranking of the expert'"'"'s employing institution, the expert'"'"'s previous success in recommending, the expert'"'"'s degree of experience, and the relatedness of the expert'"'"'s qualifications or experiences to treating or working or processing conditions of the patient.

9. The method as defined by claim 1, further comprising storing, in an outcome database, treatment decisions by a plurality of patients together with medical outcomes of the treatments and reporting to the patient information derived from the outcome database related to past outcomes.

10. The method as defined by claim 9, further comprising determining the treatment scores as a function of the success rate in the outcome database.

11. The method as defined by claim 1 further comprising formulating a medical question, the question comprising patient information, information about the medical condition, and a list of the potential treatment options.

12. The method as defined by claim 11, further comprising sending the question to a panel of experts, receiving response information from the experts about treatment options and reporting the response information to the patient.

13. The method as defined by claim 1 further comprising creating the treatment option database.

14. The method as defined by claim 1 further comprising creating a database with the indexed study data.

15. The method as defined by claim 1, wherein each study score also corresponds to an effectiveness demonstrated by the treatment option in a distinct study.

16. A computer program product including a non-transitory computer-readable medium having computer code thereon for generating a report to help decide among a plurality of treatment options for a patient for a given treatable medical condition, the computer code comprising:

computer code for receiving patient information related to the patient and the medical condition;

computer code for querying a treatment option database to generate a list of potential treatment options for the medical condition; and

computer code for receiving preference information indicative of the patient'"'"'s preference for potential treatment outcomes of the treatment options to produce a preference value;

computer code for analyzing indexed study data relating to the plurality of treatment options by at least grading evidence within the indexed study data, wherein the indexed study data is derived from scientific studies, each of which evaluates an effect of a different treatment option on different trial subjects who have a similar medical condition as the patient;

computer code for producing a study score for each of the treatment options based on the analysis of the indexed data;

computer code for determining, for each distinct treatment option, a distinct treatment score as a function of at least the preference value and the study score corresponding to the distinct treatment option; and

computer code for generating a report listing the treatment options and a) the treatment scores or b) information derived from the treatment scores.

17. The computer program as defined by claim 16 wherein the information derived from the treatment scores is a ranking of the treatment options as a function of the treatment scores for the treatment options.

18. The computer program as defined by claim 17, further comprising

computer code for determining that a difference between the highest treatment score and a next highest treatment score is larger than a threshold,

computer code for determining that no single value used to compute the highest treatment score is greater than the next highest treatment score or the values used to compute the next highest treatment score, and

computer code for selecting a recommended treatment option with a highest treatment score.

19. The computer program as defined by claim 17, further comprising

computer code for choosing two treatment options with the highest treatment scores;

and

computer code for determining if a difference between the two highest treatment scores falls below a pre-defined threshold, and if so, recalculating the treatment scores without using the preference value.

20. The computer program as define by claim 16, further comprising:

computer code for comparing the patient information with characteristics of trial subjects tested in at least one scientific study represented by the indexed study data to determine the applicability of at least one study to the patient represented by an applicability value; and

computer code for recalculating, for each treatment option, the treatment score as a function of the preference value, study score, and applicability value.

21. The computer program as defined by claim 16 further comprising:

computer code for receiving treatment recommendations from a plurality of experts, the treatment recommendations relating to the plurality of treatment options;

computer code for converting, in a computer process, the treatment recommendations into an expert score for each treatment option; and

computer code for recalculating, for each treatment option, the treatment score as a function of the preference value, study score, and expert score.

22. The computer program as define by claim 21, further comprising computer code for applying an expert weight to the expert score.

23. The computer program as defined by claim 22, wherein the expert weight is calculated using at least one of a ranking of the expert'"'"'s academic institution, a ranking of the expert'"'"'s employing institution, the expert'"'"'s previous success in recommending, the expert'"'"'s degree of experience, and the relatedness of the expert'"'"'s qualifications or experiences to treating or working or processing conditions of the patient.

24. The computer program as defined by claim 16, further comprising computer code for storing, in an outcome database, treatment decisions by a plurality of patients together with medical outcomes of the treatments and computer code for reporting to the patient information derived from the outcome database related to past outcomes.

25. The computer program as defined by claim 24, further comprising computer code for determining the treatment scores as a function of the success rate in the outcome database.

26. The computer program as defined by claim 16 further comprising computer code for formulating a medical question, the question comprising patient information, information about the medical condition, and a list of the potential treatment options.

27. The computer program as defined by claim 26, further comprising computer code for sending the question to a panel of experts, and computer code for receiving response information from the experts about treatment options and reporting the response information to the patient.

28. The computer program as defined by claim 16, wherein each study score also corresponds to an effectiveness demonstrated by the treatment option in a distinct study.

29. A medical treatment recommendation system for generating a report to help decide among a plurality of treatment options for a patient for a given treatable medical condition comprising:

a patient information receiving module executing on a computer that receives patient information related to the patient and the medical condition;

a querying module executing on a computer that queries a treatment option database to generate a list of potential treatment options for the medical condition;

a preference information receiving module executing on a computer that receives patient information indicative of the patient'"'"'s preference for potential treatment outcomes of the treatment options to produce a preference value;

an analysis module executing on a computer that analyzes indexed study data relating to the plurality of treatment options by at least grading evidence within the indexed study data, wherein the indexed study data is derived from scientific studies, each of which evaluates an effect of a different treatment option on different trial subjects who have a similar medical condition as the patient;

a study score producing module executing on a computer that produces a study score for each of the treatment options based on the analysis of the indexed data;

a treatment scoring module executing on a computer that determines for each distinct treatment option a distinct treatment score as a function of at least the preference value and study score corresponding to the distinct treatment option; and

a reporting module executing on a computer that generates a report listing the treatment options and a) the treatment scores or b) information derived from the treatment scores.

30. The system as defined by claim 29 wherein the information derived from the treatment scores is a ranking of the treatment options as a function of the treatment scores for the treatment options.

31. The system as defined by claim 30, further comprising

a module for determining that a difference between a highest treatment score and a next highest treatment score is larger than a threshold,

a module for determining that no single value used to compute the highest treatment score is greater than the next highest treatment score or the values used to compute the second highest treatment score, and

a module for selecting a recommended treatment option with the highest treatment score.

32. The system as defined by claim 30, further comprising

a module for choosing two treatment options with the highest treatment scores, and

a module for determining, if a difference between two highest treatment scores falls below a pre-defined threshold, and if so, recalculating the treatment scores without using the preference value.

33. The system as define by claim 29, further comprising:

a module for comparing the patient information with characteristics of trial subjects tested in at least one scientific study represented by the indexed study data to determine the applicability of at least one study to the patient represented by an applicability value; and

a module for recalculating, for each treatment option, the treatment score as a function of the preference value, study score, and applicability value.

34. The system as defined by claim 29 further comprising:

a module for receiving treatment recommendations from a plurality of experts, the treatment recommendations relating to the plurality of treatment options;

a module for converting, in a computer process, the treatment recommendations into an expert score for each treatment option; and

a module for recalculating, for each treatment option, the treatment score as a function of the preference value, study score, and expert score.

35. The system as define by claim 29, further comprising a module for applying an expert weight to the expert score.

36. The system as defined by claim 35, wherein the expert weight is calculated using at least one of a ranking of the expert'"'"'s academic institution, a ranking of the expert'"'"'s employing institution, the expert'"'"'s previous success in recommending, the expert'"'"'s degree of experience, and the relatedness of the expert'"'"'s qualifications or experiences to treating or working or processing conditions of the patient.

37. The system as defined by claim 29, further comprising a module for storing, in an outcome database, treatment decisions by a plurality of patients together with medical outcomes of the treatments and reporting to the patient information derived from the outcome database related to past outcomes.

38. The system as defined by claim 37, further comprising a module for determining the treatment scores as a function of the success rate in the outcome database.

39. The system as defined by claim 29 further comprising a module for formulating a medical question, the question comprising patient information, information about the medical condition, and a list of the potential treatment options.

40. The system as defined by claim 39, further comprising a module for sending the question to a panel of experts, receiving response information from the experts about treatment options and reporting the response information to the patient.

41. The system as defined by claim 29, wherein each study score also corresponds to an effectiveness demonstrated by the treatment option in a distinct study.