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Scalable parallel gene therapy injector array

  • US 8,708,965 B2
  • Filed: 11/17/2009
  • Issued: 04/29/2014
  • Est. Priority Date: 11/17/2008
  • Status: Active Grant
First Claim
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1. An injector array, comprising:

  • a plurality of capillary tubes of varying lengths, each capillary tube being individually connectible at a proximal end to a displacement-controlled pump, each capillary tube being adapted at a distal end for insertion into a brain or body part, each capillary tube being further adapted for delivery of fluidic materials through the distal end to the brain or body part, wherein the length of each individual capillary tube is individually determined according to the location of a respective one of a plurality of specific target areas in the brain or body part and at least some of the individual capillary tubes are of different lengths than others of the individual capillary tubes;

    a support structure for holding the plurality of capillary tubes such that their distal ends, taken together, terminate in a three-dimensional spatial pattern that permits delivery of the fluidic materials in parallel to the plurality of specific target areas in the brain or body part; and

    a stereotaxic device to which the support structure is attachable, the stereotaxic device being configured to control the angular orientation of the support structure with respect to the brain or body part so that the distal end of each capillary tube is positioned at its respective target area.

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