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Microneedle devices and methods of manufacture and use thereof

  • US 8,708,966 B2
  • Filed: 08/09/2010
  • Issued: 04/29/2014
  • Est. Priority Date: 06/10/1998
  • Status: Expired due to Fees
First Claim
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1. A method for delivering of active agent across a biological barrier, the method comprising the steps of:

  • puncturing the biological barrier with a plurality of microneedles, the microneedles attached to or integrally formed with a substrate, wherein each of the microneedles is formed of a biodegradable polymer and an active agent dispersed in the biodegradable polymer of the microneedles;

    delivering the active agent solely through biodegradation of the biodegradable polymer of the microneedles in the biological barrier.

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