Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall

• US 8,709,034 B2
• Filed: 05/13/2011
• Issued: 04/29/2014
• Est. Priority Date: 05/13/2011
• Status: Active Grant

• Current Assignee: Broncus Medical Incorporated
• Original Assignee: Broncus Medical Incorporated
• Inventors: Keast, Thomas M., Laufer, Michael D., Wibowo, Henky, Cole, Cary, Kaplan, Gary S., Roschak, Edmund J.
• Primary Examiner(s): FISHBACK, ASHLEY LAUREN
• Application Number:
  US13/107,720
• Publication Number:
  US 20120289776A1
• Time in Patent Office: 1,082 Days
• Field of Search: 128/898, 604/500, 604/506, 604/507, 604/508, 604/510, 606/151, 606/184, 606/185
• US Class Current: 606/185
• CPC Class Codes: A61B 1/00082 Balloons
• CPC Class Codes: A61B 1/01 Guiding arrangements therefore
• CPC Class Codes: A61B 1/2676 Bronchoscopes
• CPC Class Codes: A61B 1/313 for introducing through surgical openings, e.g. laparoscopes
• CPC Class Codes: A61B 10/0233 Pointed or sharp biopsy instruments
• CPC Class Codes: A61B 17/0293 with ring member to support retractor elements
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/3209 Incision instruments
• CPC Class Codes: A61B 17/3423 Access ports, e.g. toroid shape introducers for instruments or hands access sites for liquids A61M39/0247
• CPC Class Codes: A61B 17/3478 Endoscopic needles, e.g. for infusion biopsy needles A61B10/0233; catheters with injection needles A61M25/0067
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/0417 T-fasteners
• CPC Class Codes: A61B 2017/0419 H-fasteners
• CPC Class Codes: A61B 2017/0427 having anchoring barbs or pins extending outwardly from the anchor body
• CPC Class Codes: A61B 2017/0464 for soft tissue
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22042 Details of the tip of the guide wire
• CPC Class Codes: A61B 2017/320056 : Tunnelers
• CPC Class Codes: A61B 2017/3425 : for internal organs, e.g. heart ports
• CPC Class Codes: A61B 2018/00541 : Lung or bronchi
• CPC Class Codes: A61B 2018/00577 : Ablation
• CPC Class Codes: A61B 2034/2051 : Electromagnetic tracking systems
• CPC Class Codes: A61B 2034/2055 : Optical tracking systems
• CPC Class Codes: A61B 2034/2057 : Details of tracking cameras
• CPC Class Codes: A61B 2090/061 : for measuring dimensions, e.g. length
• CPC Class Codes: A61B 2090/3782 : transmitter or receiver in catheter or minimal invasive instrument
• CPC Class Codes: A61B 2090/3945 : Active visible markers, e.g. light emitting diodes
• CPC Class Codes: A61B 34/20 : Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/062 : using magnetic field

Abstract

Methods and devices for diagnosing, monitoring, and/or treating tissue through an opening or port through an airway wall are provided herein.

Claims

1. A method of accessing target tissue in a lung, the method comprising:

locating a target site on an airway wall, wherein the target site is in a location that allows for creation of an opening leading to the target tissue and for advancement of an elongate instrument through the opening to the target tissue;

creating an opening through the airway wall at the target site with a hole-making instrument, the opening leading to the target tissue;

advancing the elongate instrument through the opening created in the airway wall;

providing an atraumatic tipped dissector, the dissector positioned within the elongate instrument;

tunneling from the opening in the airway wall to the target tissue with the elongate instrument and the dissector positioned therein;

removing the dissector from the elongate instrument such that the elongate instrument provides access to the target tissue for performing monitoring, diagnostic or therapeutic procedures through the elongate instrument; and

performing a procedure on the target tissue with a procedure instrument through the previously positioned elongate instrument leading to the target tissue.

2. The method of claim 1, wherein the target site is in a location that allows for advancement of an elongate instrument to the target tissue along a substantially straight path.

3. The method of claim 2, wherein the target site is determined by considering one or more of the following factors:

a size of the airway;

an outer diameter of a scope used to advance the elongate instrument in the airway;

space available within the airway to articulate a scope so that the scope working channel can point towards the target tissue;

a position of blood vessels in the lung;

a location of pleural surfaces within the lung;

a location of other airways in the lung; and

/or a location, size, and/or shape of a target tissue.

4. The method of claim 1, wherein the target site is in a location that allows for advancement of an elongate instrument from the opening in the airway wall to the target tissue along a substantially straight path.

5. The method of claim 1, wherein the target site is in a location that allows for the creation of a substantially straight tunnel or channel leading from the target site or opening to the target tissue.

6. The method of claim 1, wherein locating a target site on the airway wall comprises determining a direction or orientation of a tunnel or channel in space, the tunnel or channel leading from the airway wall to the target tissue in a substantially straight line.

7. The method of claim 1, wherein the opening through the airway wall at the target site is created by advancing a piercing member to the target site and through the airway wall.

8. The method of claim 7, further comprising dilating the opening with a balloon catheter or other expandable device.

9. The method of claim 1, further comprising articulating the elongate instrument within the airway such that a distal end of the elongate instrument points in a direction facing the target tissue before the elongate instrument advances through the opening.

10. The method of claim 1,

wherein the dissector is a dissecting catheter having a rounded tip.

11. The method of claim 1, further performing imaging to guide the elongate instrument to the target tissue.

12. The method of claim 11 wherein the imaging method used is comprised of at least one of:

fluoroscopy, computed tomography, positron emission technology, magnetic resonance imaging, or ultrasound.

13. The method of claim 1, wherein the target tissue is a tumor or diseased tissue.

14. The method of claim 1, wherein the procedure instrument is a biopsy tool, and the procedure is to obtain a biopsy sample through the elongate instrument.

15. A method of accessing target tissue in a lung, the method comprising:

advancing a flexible elongate instrument to a target site in an airway of the lung;

creating an opening through the airway wall at the target site with a hole-making instrument;

advancing the elongate instrument through the opening;

urging the elongate instrument and a dissector positioned within the elongate instrument forward through lung tissue, thereby creating a tunnel from the opening in the airway wall to the target tissue;

removing the dissector from the elongate instrument such that the elongate instrument provides access to the target tissue for performing monitoring, diagnostic or therapeutic procedures through the elongate instrument; and

performing a procedure on the target tissue with a procedure instrument through the previously positioned elongate instrument leading to the target tissue.

16. The method of claim 15, wherein the elongate instrument is advanced to the target tissue along a substantially straight path.

17. The method of claim 15, wherein the elongate instrument is advanced from the opening in the airway wall to the target tissue along a substantially straight path.

18. The method of claim 15, further comprising locating a target site on an airway wall, wherein the target site is in a location that allows for creation of an opening leading to the target tissue and for advancement of the elongate instrument through the opening to the target tissue.

19. The method of claim 18, wherein the elongate instrument is advanced to the target tissue along a substantially straight path.

20. The method of claim 15, further comprising dilating the opening with a balloon catheter or other expandable device.

21. The method of claim 15, further comprising articulating the elongate instrument within the airway such that a distal end of the elongate instrument points in a direction facing the target tissue before the elongate instrument advances through the opening.

22. The method of claim 15, further comprising leaving the elongate instrument in place to provide access to the target tissue for performing monitoring, diagnostic or therapeutic procedures or for delivering instruments or tools to the target tissue.

23. The method of claim 15, further performing imaging to guide the elongate instrument to the target tissue.

24. A method of accessing target tissue in a lung, the method comprising:

selecting a target site in an airway of the lung wherein the target site is in a location that allows for creation of an opening through the airway wall, the opening leading to the target tissue, and wherein the target site is in a location that allows for advancement of a flexible elongate instrument through the opening to the target tissue along a substantially straight path;

advancing the elongate instrument to a target site in an airway of the lung;

creating an opening through the airway wall at the target site with a hole-making instrument;

advancing the elongate instrument through the opening created in the airway wall;

urging the elongate instrument and a dissector positioned within the elongate instrument forward through lung tissue, thereby creating a tunnel from the opening in the airway wall to the target tissue;

removing the dissector from the elongate instrument such that the elongate instrument provides access to the target tissue for performing monitoring, diagnostic or therapeutic procedures; and

performing a procedure on the target tissue with a procedure instrument through the previously positioned elongate instrument leading to the target tissue.

25. The method of claim 24, further performing imaging to guide the elongate instrument to the target tissue.

26. The method of claim 25 wherein the imaging method used is comprised of at least one of:

fluoroscopy, computed tomography, positron emission technology, magnetic resonance imaging, or ultrasound.