Prevention and treatment of oxidative stress disorders by gluthathione and phase II detoxification enzymes
First Claim
1. A method of treating a subject in need of treatment of an oxidative stress disorder, said method comprising administering to said subject a composition comprising an effective amount of a compound that elevates intracellular levels of glutathione or intracelluar levels of at least one Phase IT detoxification enzyme in diseased tissue of said subject, wherein said oxidative stress disorder is selected from the group consisting of Alzheimer'"'"'s Disease and aging.
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Abstract
The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders.
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Citations
14 Claims
- 1. A method of treating a subject in need of treatment of an oxidative stress disorder, said method comprising administering to said subject a composition comprising an effective amount of a compound that elevates intracellular levels of glutathione or intracelluar levels of at least one Phase IT detoxification enzyme in diseased tissue of said subject, wherein said oxidative stress disorder is selected from the group consisting of Alzheimer'"'"'s Disease and aging.
- 5. A method of protecting a subject from an oxidative stress disorder, said method comprising administering to said subject a composition comprising an effective amount of a compound that elevates intracellular levels of glutathione or intracellular levels of at least one Phase II detoxification enzyme in diseased tissue of said subject, wherein said oxidative stress disorder is selected from the group consisting of Alzheimer'"'"'s Disease and aging.
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