Quantitative sleep analysis system and method

• US 8,712,513 B1
• Filed: 11/15/2012
• Issued: 04/29/2014
• Est. Priority Date: 06/04/2003
• Status: Expired due to Fees

• Current Assignee: Cleveland Medical Devices Inc.
• Original Assignee: Cleveland Medical Devices Inc.
• Inventors: Modarres, Mo
• Primary Examiner(s): Natnithithadha, Navin
• Application Number:
  US13/677,469
• Time in Patent Office: 530 Days
• Field of Search: 600/544, 600/545
• US Class Current: 600/544
• CPC Class Codes: A61B 5/374 Detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/4806 Sleep evaluation A61B5/4821 takes precedence; devices for inducing sleep A61M21/02
• CPC Class Codes: A61B 5/4818 Sleep apnoea

Abstract

The present invention relates to a method of analyzing a subject for excessive daytime sleepiness, and more particularly to a quick (short duration), quantitative method of sleep disorder analysis. The present invention additionally relates to a method that can be used to quantitatively measure the treatment endpoints for the subject, i.e., appropriate levels of stimulants. Additionally, the present invention relates to a device for sleep disorder analysis.

Claims

1. A system for analyzing sleep disorders of a subject comprising:

at least one brain wave sensor that measures brain wave signals;

a component for delivering a stimulus to a subject;

a component for measuring a response by the subject to the delivered stimulus; and

a processor or computer that analyzes the measured brain wave signals in relation to the stimulus to and the measured response from the subject, and determines whether the subject suffers from a sleeping disorder based on the analysis of the measured brain wave signals in relation to the stimulus to and the measured response from the subject.

2. The system in claim 1, wherein the at least sensor is a dry electrode.

3. The system in claim 1, wherein the sleeping disorder is quantitatively analyzed by the processor or computer.

4. The system in claim 1, wherein the stimulus is provided on an intermittent basis.

5. The system in claim 4, wherein the stimulus is one or more auditory signals.

6. The system in claim 1, wherein the processor or computer is additionally used to quantify scope of the sleep disorder.

7. The system in claim 6, wherein a power spectrum profile having alpha and one or more sub-alpha components is determined for the filtered brain wave signal and the determination of whether the subject suffers from a sleeping disorder is further based in part on the ratio of the alpha to the one or more sub-alpha components.

8. A system for analyzing sleep disorders of a subject comprising:

at least two brain wave sensors that measures brain wave signals;

a component for delivering at least different types of stimuli to a subject;

a component for subject to receive the delivered stimuli;

a component for measuring a response by the subject to the delivered stimuli; and

a processor or computer that analyzes the measured brain wave signals in relation to the stimuli to and response from the subject, and determines whether the subject suffers from a sleeping disorder based on the analysis of the measured brain wave signals in relation to the stimuli to and response from the subject.

9. The system in claim 8, wherein at least one of the at least two sensors is a dry electrode.

10. The system in claim 8, wherein the sleeping disorder is quantitatively analyzed by the processor or computer.

11. The system in claim 8, wherein the stimuli are provided on an intermittent basis.

12. The system in claim 11, wherein the stimulus is one or more auditory signals.

13. The system in claim 8, wherein the processor or computer is additionally used to quantify scope of the sleep disorder.

14. The system in claim 13, wherein a power spectrum profile from about 0 to 30 Hz is determined for the filtered brain wave signal in part in order to determine whether the subject has a sleeping disorder.

15. The system in claim 14, wherein determination of whether the subject suffers from a sleeping disorder is further based in part on the sum of the power between 0.5 and 7.5 Hz divided by the sum of the power between 7.5 and 13 Hz.

16. A system for analyzing sleep disorders of a subject comprising:

at least one brain wave sensor that measures brain wave signals;

a component for delivering a non-continuous stimulus to a subject for at least 10 minutes;

a component for measuring, at least at 200 Hz, a response by the subject to the delivered stimuli; and

a processor or computer that analyzes the measured brain wave signals in relation to the stimuli to and the measured response from the subject, and determines whether the subject suffers from a sleeping disorder based on the analysis of the measured brain wave signals in relation to the stimuli to and the measured response from the subject.

17. The system of claim 16, wherein the at least one sensor is a dry electrode.

18. The system of claim 16, wherein the non-continuous stimulus is delivered at 1.5 second intervals.

19. The system of claim 18, wherein the non-continuous stimulus one or more auditory signals.

20. The system in claim 16, wherein the processor or computer is additionally used to quantify scope of the sleep disorder.