Eye therapy system

• US 8,712,536 B2
• Filed: 04/02/2010
• Issued: 04/29/2014
• Est. Priority Date: 04/02/2009
• Status: Expired due to Fees

• Current Assignee: Avedro, Inc. (Glaukos Corporation)
• Original Assignee: Avedro, Inc. (Glaukos Corporation)
• Inventors: Muller, David, Ryan, Thomas, Scharf, Ronald
• Primary Examiner(s): Kahelin, Michael
• Assistant Examiner(s): ALTER MORSCHAUSER, ALYSSA MARGO
• Application Number:
  US12/753,523
• Publication Number:
  US 20100256705A1
• Time in Patent Office: 1,488 Days
• Field of Search: 607/53
• US Class Current: 607/53
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/0079 using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
• CPC Class Codes: A61F 9/013 Instruments for compensation of ocular refraction A61F9/008 takes precedence; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
• CPC Class Codes: A61N 1/403 for thermotherapy, e.g. hyperthermia

Abstract

An electrical energy applicator in one embodiment extends from a proximal end to a distal end. The energy conducting applicator includes, at the proximal end, a connection to one or more electrical energy sources. The energy conducting applicator directs electrical energy from the one or more electrical energy sources to the distal end. The energy conducting applicator includes an outer conductor and an inner conductor extending to the distal end. The outer conductor and the inner conductor are separated by a gap. The outer conductor includes a plurality of moveable outer segments and the inner conductor includes a plurality of moveable inner segments. The plurality of outer segments and the plurality of inner segments form a total contact surface at the distal end. The total contact surface is positionable at a surface of an eye. The electrical energy is applied to the eye according to the total contact surface.

Claims

1. A system for applying thermokeratoplasty to an eye, the system comprising:

an electrical energy source; and

an electrical energy conducting element extending from a proximal end to a distal end, the energy conducting element electrically connected to the electrical energy source at the proximal end, the energy conducting element including;

an outer conductor extending to the distal end, the outer conductor including a plurality of moveable outer segments; and

an inner conductor extending to the distal end and disposed within the outer conductor, the inner conductor including a plurality of moveable inner segments, the outer conductor and the inner conductor being separated by a gap, the plurality of outer segments and the plurality of inner segments forming a total contact surface at the distal end, the total contact surface being positionable at a corneal surface of an eye such that an energy is applied to the eye according to the total contact surface to cause shrinkage of corneal tissue of the eye in response to the electrical connection between the energy conducting element and the electrical energy source,

wherein each of the plurality of outer segments is individually and separately moveable and each of the plurality of inner segments is individually and separately moveable.

2. The system of claim 1, wherein the total contact surface corresponds to the shape of a cornea.

3. The system of claim 1, wherein the plurality of outer segments and the plurality of inner segments are operable to adjust to the shape of the eye.

4. The system of claim 1, wherein the plurality of outer segments and the plurality of inner segments extend from an intermediate section of the conducting element to the distal end, the intermediate section being between the proximal end and the distal end.

5. The system of claim 4, wherein the plurality of outer conductors and the plurality of inner conductors are connected to the intermediate section by one or more coupling devices.

6. The system of claim 1 further comprising at least one biasing member, the at least one biasing member biasing the plurality of outer segments and the plurality of inner segments towards the distal end.

7. The system of claim 1, wherein the plurality of outer segments and the plurality of inner segments are substantially cylindrical at the distal end.

8. The system of claim 1, wherein the plurality of outer segments and the plurality of inner segments are moveable between the proximal end and the distal end.

9. The system of claim 1, wherein at least one of the outer segments and at least one of the inner segments are operable to be fixed at one or more positions between the proximal end and the distal end.

10. The system of claim 9, wherein the position at which the at least one outer segment and the at least one inner segment are fixed is dependent upon a pattern of energy to be applied to the eye.

11. The system of claim 10, wherein the pattern is asymmetric.

12. The system of claim 9, wherein the position at which the at least one outer segment and the at least one inner segment are fixed is dependent upon a selected depth of penetration of the energy to be applied to the eye.

13. The system of claim 1, wherein the gap is a substantially annular gap.

14. The system of claim 1 further comprising a controller configured to control the supply of electrical energy to each outer segment and each inner segment, each outer segment and each inner segment being individually coupled to the electrical energy source.

15. The system of claim 1, wherein each outer segment is spaced apart from each adjacent outer segment such that the plurality of outer segments collectively act as a single outer conductor and each inner segment is spaced apart from each adjacent inner segment such that the plurality of inner segments collectively act as a single inner conductor.

16. The system of claim 1 further comprising a layer of dielectric material disposed on at least a portion of the total contact surface, the layer of dielectric material being configured to substantially inhibit an electrical current from the inner conductor and the outer conductor into the corneal tissue while allowing a microwave heating pattern to be applied to the eye according to the total contact surface to cause shrinkage of corneal tissue of the eye in response to the electrical connection between the energy conducting element and the electrical energy source.

17. A method for applying thermokeratoplasty to an eye, the method comprising:

positioning a total contact surface of an electrical energy conducting element at a corneal surface of an eye, the energy conducting element being operably connected to an electrical energy source at a proximal end and extending to the total contact surface at a distal end, the energy conducting element including;

an outer conductor extending to the distal end, the outer conductor including a plurality of moveable outer segments; and

an inner conductor extending to the distal end and disposed within the outer conductor, the inner conductor including a plurality of moveable inner segments, the outer conductor and the inner conductor being separated by a gap, the plurality of outer segments and the plurality of inner segments forming the total contact surface at the distal end; and

applying energy from the electrical energy conducting element to the eye according to the total contact surface to cause shrinkage of corneal tissue of the eye,

wherein each of the plurality of outer segments is individually and separately moveable and each of the plurality of inner segments is individually and separately moveable.

18. The method of claim 17, wherein the total contact surface corresponds to the shape of a cornea.

19. The method of claim 17, wherein the plurality of outer segments and the plurality of inner segments are operable to adjust to the shape of the eye.

20. The method of claim 17, wherein the contact surface is positioned at the eye such that the contact surface applies a uniform pressure on the eye.

21. The method of claim 17, wherein the electrical energy conducting unit includes at least one biasing member, the at least one biasing member biasing the plurality of outer segments and the plurality of inner segments towards the distal end.

22. The method of claim 17, wherein the plurality of outer segments and the plurality of inner segments are substantially cylindrical at the distal end.

23. The method of claim 17 further comprising moving at least one outer segment to a position between the distal end and the proximal end.

24. The method of claim 23, wherein the position is selected such that the at least one outer segment does not contact the eye.

25. The method of claim 17 further comprising moving at least one inner segment to a position between the distal end and the proximal end.

26. The method of claim 25, wherein the position is selected such that the at least one inner segment does not contact the eye.

27. The method of claim 17 further comprising moving at least one outer segment and at least one inner segment to achieve at least one of the group consisting of a selected pattern of energy applied to the eye and a selected depth of penetration of energy into the eye.

28. The method of claim 27, wherein the pattern is asymmetric.

29. The method of claim 17 further comprising supplying energy from the electrical energy source to one or more outer segments and one or more inner segments.

30. The method of claim 29, wherein the energy is not supplied to at least one outer segment.

31. The method of claim 29, wherein the energy is not supplied to at least one inner segment.

32. The method of claim 17 further comprising selectively supplying energy to at least one outer segment and at least one inner segment to apply energy to a cornea according to an asymmetric pattern.

33. A system for applying thermokeratoplasty to an eye, the system comprising:

an electrical energy source; and

an electrical energy conducting element extending from a proximal end to a distal end, the energy conducting element electrically connected to the electrical energy source at the proximal end, the energy conducting element including;

an outer conductor extending along a longitudinal axis to the distal end, the longitudinal axis being generally in a direction from the proximal end to the distal end, the outer conductor having an interior surface, the outer conductor including a plurality of moveable outer segments, the plurality of moveable outer segments being configured to be individually and separately moveable along the longitudinal axis;

an inner conductor extending along the longitudinal axis to the distal end and disposed within the outer conductor, the inner conductor including a plurality of moveable inner segments, the plurality of moveable inner segments are configured to be individually and separately moveable along the longitudinal axis, the inner conductor having an exterior surface separated from the interior surface of the outer conductor by a gap, the gap extending entirely around the exterior surface of the inner conductor; and

a flexible sheath-like structure of dielectric material covering the distal end configured to substantially inhibit an electrical current from the inner conductor and the outer conductor into the corneal tissue, the plurality of outer segments and the plurality of inner segments forming a total contact surface at the distal end, the total contact surface being positionable at a corneal surface of an eye such that a microwave energy is applied to the eye according to the total contact surface to cause shrinkage of corneal tissue of the eye in response to the electrical connection between the energy conducting element and the electrical energy source.