Methods and systems for presenting an inhalation experience

• US 8,712,794 B2
• Filed: 04/27/2009
• Issued: 04/29/2014
• Est. Priority Date: 12/30/2008
• Status: Active Grant

• Current Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Hyde, Roderick A., Langer, Robert, Leuthardt, Eric C., Lord, Robert W., Sweeney, Elizabeth A., Tegreene, Clarence T., Wood, Lowell L. Jr.
• Primary Examiner(s): NGUYEN, HIEP VAN
• Application Number:
  US12/387,057
• Publication Number:
  US 20100164729A1
• Time in Patent Office: 1,828 Days
• Field of Search: 705/2
• US Class Current: 705/2
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/02 Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0065 Inhalators with dosage or measuring devices A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 15/02 with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2021/0016 : by the smell sense
• CPC Class Codes: A61M 2205/3553 : remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3569 : sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3584 : using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/3592 : using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/50 : with microprocessors or computers
• CPC Class Codes: A61M 2205/581 : by audible feedback
• CPC Class Codes: A61M 2205/582 : by tactile feedback
• CPC Class Codes: A61M 2205/583 : by visual feedback
• CPC Class Codes: A61M 2205/588 : by olfactory feedback, i.e. smell
• CPC Class Codes: A61M 2209/088 : on the body
• CPC Class Codes: A61M 2230/201 : Glucose concentration
• CPC Class Codes: A61M 2230/205 : partial oxygen pressure (P-O2)
• CPC Class Codes: A63F 2300/65 : for computing the condition of a game character
• CPC Class Codes: A63F 2300/6692 : using special effects, generally involving post-processing, e.g. blooming
• CPC Class Codes: G16H 20/13 : delivered from dispensers

Abstract

Methods, computer program products, and systems are described that include accepting an indication of an individual'"'"'s compliance with an artificial sensory experience and presenting an indication of an inhalation device-dispensed bioactive agent at least partially based on the indication of the individual'"'"'s compliance with the artificial sensory experience.

Claims

1. A system, comprising:

means for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience;

means for determining at least one agent associated with at least one bioactive effect at least partially based on the means for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience; and

means for presenting at least one indication at least partially based on the means for determining at least one agent associated with at least one bioactive effect.

2. The system of claim 1, wherein the means for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

means for accepting at least one report related to the at least one individual'"'"'s compliance from at least one virtual world experience provider.

3. The system of claim 1, wherein the means for determining at least one agent associated with at least one bioactive effect at least partially based on the means for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

means for utilizing at least one algorithm configured for comparing at least one effect of the at least one agent associated with at least one bioactive effect with at least one expected behavior of the at least one individual at one or more times substantially proximate to the at least one individual'"'"'s use of the at least one virtual world experience.

4. The system of claim 1, wherein the means for presenting at least one indication at least partially based on the means for determining at least one agent associated with at least one bioactive effect comprises:

means for selectively presenting the at least one indication only to the at least one individual.

5. A system, comprising:

a computing device; and

one or more instructions that when executed on the computing device cause the computing device to

accept at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience;

determine at least one agent associated with at least one bioactive effect at least partially based on the at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience; and

present at least one indication at least partially based on the at least one agent associated with at least one bioactive effect.

6. The system of claim 5, wherein the computing device comprises:

one or more of a personal digital assistant (PDA), a personal entertainment device, a mobile phone, a laptop computer, a tablet personal computer, a networked computer, a computing system comprised of a cluster of processors, a computing system comprised of a cluster of servers, a workstation computer, or a desktop computer.

7. The system of claim 5, wherein the computing device is operable to accept the at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience, determine the at least one agent associated with at least one bioactive effect at least partially based on the at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience, and present the at least one indication at least partially based on the at least one agent associated with at least one bioactive effect from at least one memory.

8. The system of claim 5, wherein, in causing the computing device to accept at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience, the one or more instructions cause the computing device to:

accept at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience prescribed for the at least one individual.

9. The system of claim 5, wherein, in causing the computing device to determine at least one agent associated with at least one bioactive effect at least partially based on the at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience, the one or more instructions cause the computing device to:

determine a compatibility between the at least one virtual world experience and the at least one agent associated with at least one bioactive effect using at least one of at least one medical history, at least some experimental data, or at least one medical reference book.

10. The system of claim 5, wherein, in causing the computing device to present at least one indication at least partially based on the at least one agent associated with at least one bioactive effect, the one or more instructions cause the computing device to:

present at least one identification of at least one prescribed inhalation device-dispensed bioactive agent.

11. A computer-implemented method, comprising:

accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience;

determining at least one agent associated with at least one bioactive effect at least partially based on the at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience; and

presenting at least one indication at least partially based on the at least one agent associated with at least one bioactive effect,

wherein at least one of the accepting, determining, or presenting is at least partially implemented using computing hardware.

12. The computer-implemented method of claim 11, wherein accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

accepting at least one report related to self compliance by the at least one individual.

13. The computer-implemented method of claim 11, wherein determining at least one agent associated with at least one bioactive effect at least partially based on the at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience comprises:

utilizing at least one algorithm configured for matching at least one detected physiologic attribute of the at least one individual with at least one prescription inhalation device-dispensed medication at one or more times substantially proximate to the at least one individual'"'"'s use of the at least one virtual world experience.

14. The computer-implemented method of claim 11, wherein presenting at least one indication at least partially based on the at least one agent associated with at least one bioactive effect comprises:

presenting at least one effect of the at least one agent associated with at least one bioactive effect in near real time.

15. A computer program product, comprising:

at least one non-transitory computer-readable medium including at least;

one or more instructions for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience;

one or more instructions for determining at least one agent associated with at least one bioactive effect at least partially based on the one or more instructions for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience; and

one or more instructions for presenting at least one indication at least partially based on the one or more instructions for determining at least one agent associated with at least one bioactive effect.

16. The computer program product of claim 15, wherein the one or more instructions for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprise:

one or more instructions for accepting at least one report related to the at least one individual'"'"'s compliance from at least one health care provider.

17. The computer program product of claim 15, wherein the one or more instructions for determining at least one agent associated with at least one bioactive effect at least partially based on the one or more instructions for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprise:

one or more instructions for indicating at least one of one or more recommended dosages or one or more recommended delivery methods.

18. The computer program product of claim 15, wherein the one or more instructions for presenting at least one indication at least partially based on the one or more instructions for determining at least one agent associated with at least one bioactive effect comprise:

one or more instructions for indicating at least one side effect of the at least one agent associated with at least one bioactive effect.

19. A system, comprising:

circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience;

circuitry for determining at least one agent associated with at least one bioactive effect at least partially based on the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience; and

circuitry for presenting at least one indication at least partially based on the circuitry for determining at least one agent associated with at least one bioactive effect.

20. The system of claim 19, wherein the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

circuitry for accepting at least one indication related to usage of at least one virtual world experience by the at least one individual.

21. The system of claim 20, wherein the circuitry for accepting at least one indication related to usage of at least one virtual world experience by the at least one individual comprises:

circuitry for accepting at least one indication of computer usage.

22. The system of claim 21, wherein the circuitry for accepting at least one indication of computer usage comprises:

circuitry for accepting at least one indication of at least one of virtual world usage or a computer activity log.

23. The system of claim 20, wherein the circuitry for accepting at least one indication related to usage of at least one virtual world experience by the at least one individual comprises:

circuitry for accepting at least one indication of interactive device usage.

24. The system of claim 19, wherein the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

circuitry for accepting at least one output from at least one of one or more presence detectors or one or more location reporting devices.

25. The system of claim 24, wherein the circuitry for accepting at least one output from at least one of one or more presence detectors or one or more location reporting devices comprises:

circuitry for accepting at least one output from at least one of one or more infrared detectors, one or more motion detectors, or one or more radio-frequency identification systems.

26. The system of claim 19, wherein the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

circuitry for accepting at least one indication of one or more physiological measurements.

27. The system of claim 26, wherein the circuitry for accepting at least one indication of one or more physiological measurements comprises:

circuitry for accepting at least one indication of at least one of a respiratory rate, body weight, body mass index number, heart rate, blood oxygen level, or blood pressure proximate to administration of the bioactive agent.

28. The system of claim 26, wherein the circuitry for accepting at least one indication of one or more physiological measurements comprises:

circuitry for continuously monitoring at least one parameter of at least one physiological measurement.

29. The system of claim 26, wherein the circuitry for accepting at least one indication of one or more physiological measurements comprises:

circuitry for accepting at least one indication of at least one current parameter value compared with at least one expected parameter value.

30. The system of claim 19, wherein the circuitry for determining at least one agent associated with at least one bioactive effect at least partially based on the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

circuitry for utilizing at least one algorithm configured for recommending the at least one agent associated with at least one bioactive effect.

31. The system of claim 30, wherein the circuitry for utilizing at least one algorithm configured for recommending the at least one agent associated with at least one bioactive effect comprises:

circuitry for utilizing at least one algorithm configured for identifying at least one contraindication of the at least one agent associated with at least one bioactive effect.

32. The system of claim 19, wherein the circuitry for presenting at least one indication at least partially based on the circuitry for determining at least one agent associated with at least one bioactive effect comprises:

circuitry for presenting the at least one indication to at least one output device.

33. The system of claim 32, wherein the circuitry for presenting the at least one indication to at least one output device comprises:

circuitry for presenting the at least one indication including at least via at least one user interface.

34. The system of claim 32, wherein the circuitry for presenting the at least one indication to at least one output device comprises:

circuitry for presenting the at least one indication to at least one mobile device.

35. The system of claim 19, wherein the circuitry for presenting at least one indication at least partially based on the circuitry for determining at least one agent associated with at least one bioactive effect comprises:

circuitry for presenting the at least one indication to at least one third party.

36. The system of claim 35, wherein the circuitry for presenting the at least one indication to at least one third party comprises:

circuitry for presenting the at least one indication to at least one health care provider.

37. The system of claim 19, wherein the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience, the circuitry for determining at least one agent associated with at least one bioactive effect at least partially based on the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience, and the circuitry for presenting at least one indication at least partially based on the circuitry for determining at least one agent associated with at least one bioactive effect comprise:

circuitry for accepting a self report by an individual of compliance with a prescription for a virtual world configured to reduce breathing difficulty and circuitry for presenting a prescribed dosage for an inhaler-dispensed bronchodilator at least partly based on the self report.

38. The system of claim 19, wherein the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience comprises:

circuitry for accepting an indication of an individual'"'"'s compliance with an artificial sensory experience.

39. The system of claim 19, wherein the circuitry for determining at least one agent associated with at least one bioactive effect at least partially based on the circuitry for accepting at least one indication related to at least one individual'"'"'s compliance with at least one virtual world experience and the circuitry for presenting at least one indication at least partially based on the circuitry for determining at least one agent associated with at least one bioactive effect comprise:

circuitry for presenting an indication of an inhalation device-dispensed bioactive agent at least partially based on the indication of the individual'"'"'s compliance with the artificial sensory experience.

40. The system of claim 19, wherein the circuitry for determining at least one agent associated with at least one bioactive effect at least partially based on the circuitry for accepting at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience comprises:

circuitry for determining at least one agent associated with at least one central nervous system effect at least partially based on the circuitry for accepting at least one indication related to the at least one individual'"'"'s compliance with the at least one virtual world experience.