Aortic valve stent graft

• US 8,715,337 B2
• Filed: 11/04/2008
• Issued: 05/06/2014
• Est. Priority Date: 11/09/2007
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Inventors: Chuter, Timothy A M
• Primary Examiner(s): Sweet, Thomas J
• Assistant Examiner(s): Mathew, Seema
• Application Number:
  US12/264,740
• Publication Number:
  US 20090125098A1
• Time in Patent Office: 2,009 Days
• Field of Search: 623/1.15, 623/1.19, 623/1.53, 623/2.1, 623/1.13, 623/1.16, 623/1.24, 623/1.35, 623/2.18, 623/1.31, 606/158
• US Class Current: 623/1.16
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0007 for adjusting length
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/006 modular

Abstract

An implantable endoluminal prosthesis for replacing a damaged aortic valve is provided. In one embodiment, the prosthesis includes a balloon-expandable stent, a tubular conduit that extends into the ascending aorta, and a self-expanding stent. The tubular conduit extends across the balloon-expandable stent. The tubular conduit includes an artificial valve. The self-expanding stent extends across the tubular conduit into the ascending aorta. The balloon-expandable stent, the tubular conduit, and the self-expanding stent are coupled to provide unidirectional flow of fluid into the aorta and further into the coronary arteries. Also provided is a method for implanting the endoluminal prosthesis.

Claims

1. An endoluminal prosthesis having an inflow end and an outflow end that is downstream of the inflow end, the prosthesis comprising:

a first stent at the inflow end of the prosthesis, wherein the first stent is configured to lie at least partially within a native valve annulus;

a tubular conduit comprising an aortic valve replacement, the aortic valve replacement positioned downstream of the first stent, wherein at least a portion of the tubular conduit overlaps at least a portion of the first stent; and

a second stent downstream of the first stent that overlaps at least a portion of the tubular conduit,

wherein ones of the first stent, tubular conduit, and the second stent are coaxially arranged for unidirectionally passing fluid through the prosthesis, and

wherein the first and second stents lack an overlapping relationship with one another,

wherein the first stent and the tubular conduit are configured to allow fluid to pass unidirectionally therethrough,

wherein an outflow end of the tubular conduit terminates at a location between proximal and distal ends of the second stent,

wherein the second stent comprises at least one uncovered region, distal to the aortic valve replacement, to allow fluid to pass radially outside of an outer perimeter of the second stent after passing through the aortic valve replacement,

wherein the second stent comprises a proximal zone having a first diameter and a distal zone having a second diameter, where the first diameter is narrower than the second diameter, and there is a taper between the first and second diameters, and

wherein the taper of the second stent is positioned at least partially downstream of the aortic valve replacement.

2. The endoluminal prosthesis of claim 1, wherein the first stent comprises a balloon-expandable stent and the second stent comprises a self-expanding stent.

3. The endoluminal prosthesis of claim 2, wherein the self-expanding stent at least partially surrounds the tubular conduit, and the tubular conduit at least partially surrounds the balloon-expandable stent.

4. The endoluminal prosthesis of claim 2, wherein both the balloon-expandable stent and the self-expanding stent at least partially surround an exterior surface of the tubular conduit.

5. The endoluminal prosthesis of claim 1, wherein the aortic valve replacement comprises an artificial valve.

6. The endoluminal prosthesis of claim 1, wherein the aortic valve replacement is located at the distal end of the tubular conduit.

7. The endoluminal prosthesis of claim 1 further comprising one or more barbs.

8. The endoluminal prosthesis of claim 1, wherein at least one of the first stent or the second stent comprises a braided bottle stent.

9. A prosthesis for replacing an aortic valve, the prosthesis having an inflow end and an outflow end that is downstream of the inflow end, the prosthesis comprising:

at least first, second and third tubular members,

wherein the second tubular member comprises a valve,

wherein the first tubular member is at the inflow end of the prosthesis and exerts a force upon the coronary sinus and the third tubular member is at the outflow end of the prosthesis and exerts a force upon the ascending aorta,

wherein the first tubular member and the second tubular member are configured to allow fluid to pass unidirectionally therethrough,

wherein a distal end of the second tubular member terminates at a location between proximal and distal ends of the third tubular member,

wherein the third tubular member comprises a proximal zone having a first diameter and a distal zone having a second diameter, where the first diameter is narrower than the second diameter, wherein there is a taper between the first and second diameters of the third tubular member,

wherein an open mesh of the third tubular member allows fluid to pass radially outside of an outer perimeter of the third tubular member after passing through the valve, and

wherein the taper of the third tubular member is positioned at least partially downstream of the valve.

10. The prosthesis of claim 9, wherein at least the first tubular member comprises a balloon-expandable stent.

11. The prosthesis of claim 9, wherein at least the third tubular member comprises a braided bottle stent.

12. The prosthesis of claim 9, wherein at least one of the first and third tubular members comprises a self-expanding stent.

13. The prosthesis of claim 9, wherein the second tubular member comprises a tubular conduit, wherein the valve is located at a distal end of the tubular conduit.

14. The prosthesis of claim 9 further comprising one or more barbs.