Device and method for particle therapy monitoring and verification
First Claim
1. A device for monitoring and verification of treatment beam delivery to a target, with a particle radiation apparatus, said treatment beam comprising one or more treatment sub beams corresponding one or more treatment beam layers, said treatment beam layers being characterized by a set of treatment beam layer parameters, said particle radiation apparatus being configurable for a given set of treatment beam layer parameters, said device comprising:
- an acquirer configured to acquire treatment beam layer parameters for said one or more treatment beam layers;
an electronic 2D detector device configured to;
be placed between the particle irradiation apparatus and the target, andmeasure 2D responses of said treatment beam layer in a plane essentially perpendicular to the central axis of said treatment beam;
a 2D detector response predicting module configured to determine predicted 2D detector responses for said one or more treatment beam layers to be delivered with said particle radiation apparatus configured with said given set of treatment beam layer parameters;
a memory to store the predicted 2D detector responses of each said one or more treatment beam layers;
an acquirer configured to acquire in real time the 2D detector responses caused by said one or more treatment beam layers delivered by said particle radiation apparatus being configured with said given set of treatment beam layer parameters;
a 2D detector response comparison module configured to perform a comparison between the measured 2D detector responses and the corresponding said predicted 2D detector responses; and
an error handling module configured to signal the difference between said measured 2D detector responses and said predicted 2D detector responses, and wherein said 2D detector response predicting module further comprises;
a 2D detector fluence calculation device configured to calculate the particle fluence at the 2D detector position for said treatment beam layer parameters;
said article fluence calculation device comprising a beam model said beam model being based on a set of beam model parameters, said beam model parameters comprising characteristics of the particle radiation apparatus and said particles;
a 2D detector response calculation device configured to calculate for a given said article fluence at the 2D detector position the corresponding 2D detector responses said 2D detector response calculation device comprising a detector model of said 2D detector device describing the geometry of the 2D detector and a detector response model describing the response of the 2D detector to particle irradiation.
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Abstract
The present invention relates to a device and method for monitoring and verification of the quality of a radiation treatment beam in conformal radiation therapy, and in particular for IMPT (Intensity Modulated Particle Therapy) applications. The device comprises a 2D electronic detector measuring 2D responses to the delivered treatment beam. These 2D responses are compared with predicted 2D responses and differences in responses are signalled. Based on the measured 2D responses the effectively delivered 3D dose distribution in the target can be reconstructed.
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Citations
19 Claims
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1. A device for monitoring and verification of treatment beam delivery to a target, with a particle radiation apparatus, said treatment beam comprising one or more treatment sub beams corresponding one or more treatment beam layers, said treatment beam layers being characterized by a set of treatment beam layer parameters, said particle radiation apparatus being configurable for a given set of treatment beam layer parameters, said device comprising:
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an acquirer configured to acquire treatment beam layer parameters for said one or more treatment beam layers; an electronic 2D detector device configured to; be placed between the particle irradiation apparatus and the target, and measure 2D responses of said treatment beam layer in a plane essentially perpendicular to the central axis of said treatment beam; a 2D detector response predicting module configured to determine predicted 2D detector responses for said one or more treatment beam layers to be delivered with said particle radiation apparatus configured with said given set of treatment beam layer parameters; a memory to store the predicted 2D detector responses of each said one or more treatment beam layers; an acquirer configured to acquire in real time the 2D detector responses caused by said one or more treatment beam layers delivered by said particle radiation apparatus being configured with said given set of treatment beam layer parameters; a 2D detector response comparison module configured to perform a comparison between the measured 2D detector responses and the corresponding said predicted 2D detector responses; and an error handling module configured to signal the difference between said measured 2D detector responses and said predicted 2D detector responses, and wherein said 2D detector response predicting module further comprises; a 2D detector fluence calculation device configured to calculate the particle fluence at the 2D detector position for said treatment beam layer parameters;
said article fluence calculation device comprising a beam model said beam model being based on a set of beam model parameters, said beam model parameters comprising characteristics of the particle radiation apparatus and said particles;a 2D detector response calculation device configured to calculate for a given said article fluence at the 2D detector position the corresponding 2D detector responses said 2D detector response calculation device comprising a detector model of said 2D detector device describing the geometry of the 2D detector and a detector response model describing the response of the 2D detector to particle irradiation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19)
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14. A method for verifying treatment beam delivery from a particle radiation apparatus prior to the irradiation of a target, said method comprising:
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providing a particle radiation apparatus for delivery of a treatment beam to the target, said treatment beam comprising one or more treatment sub beams, the one or more treatment sub beams being defined as a treatment beam layer corresponding to an irradiation layer and comprising particles having essentially the same energy, the one or more treatment beam layers being characterized by a set of treatment beam layer parameters, said particle radiation apparatus being configurable for a given set of treatment beam layer parameters, providing an acquirer configured to acquire prescribed treatment beam layer parameters; providing, between the particle irradiation apparatus and the target, a 2D detector device configured to provide a measured 2D detector response of said treatment beam layer in a plane perpendicular to the central axis of said treatment beam; for the one or more beam layers, determining a predicted 2D detector response for said prescribed treatment beam layer parameters, said step of determining a predicted 2D detector response compromising; computing the particle fluence at the 2D detector position using the set of prescribed treatment beam layer parameters as input data and by using a beam model with a set of predetermined beam model parameters, computing the predicted 2D detector response using the particle fluence at the 2D detector position as input data and by using a detector model describing the geometry of the 2D detector and a detector response model describing the response of the 2D detector to particle irradiation; delivering said treatment beam layer to the target with said particle radiation apparatus being configured with said prescribed treatment beam layer parameters; measuring the 2D detector responses caused by the treatment beam layer delivered by said particle radiation apparatus; performing a comparison between the measured 2D detector response and the corresponding predicted 2D detector response; and signalling difference between said measured 2D detector response and said predicted 2D detector response. - View Dependent Claims (15, 16, 17, 18)
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Specification