X-ray tomography method and apparatus used in conjunction with a charged particle cancer therapy system

• US 8,718,231 B2
• Filed: 02/16/2012
• Issued: 05/06/2014
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Balakin
• Inventors: Balakin, Vladimir
• Primary Examiner(s): Ho, Allen C.
• Application Number:
  US13/398,446
• Publication Number:
  US 20120209109A1
• Time in Patent Office: 810 Days
• Field of Search: 378/10, 378/20, 378/65, 378/68, 378/69, 378/209, 250/492.3
• US Class Current: 378/65
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/0421 with immobilising means
• CPC Class Codes: A61N 2005/1061 using an x-ray imaging system having a separate imaging source
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1097 Means for immobilizing the patient
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: A61N 5/1064 for adjusting radiation treatment in response to monitoring
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/107 in real time, i.e. during treatment

Abstract

The invention comprises an X-ray tomography method and apparatus used in conjunction with multi-axis charged particle or proton beam radiation therapy of cancerous tumors. In various embodiments, 3-D images are generated from a series of 2-D X-rays images; the X-ray source and detector are stationary while the patient rotates; the 2-D X-ray images are generated using an X-ray source proximate a charged particle beam in a charged particle cancer therapy system; and the X-ray tomography system uses an electron source having a geometry that enhances an electron source lifetime, where the electron source is used in generation of X-rays. The X-ray tomography system is optionally used in conjunction with systems used to both move and constrain movement of the patient, such as semi-vertical, sitting, or laying positioning systems. The X-ray images are optionally used in control of a charged particle cancer therapy system.

Claims

1. An apparatus for positioning a patient for imaging of a tumor with X-rays, comprising:

a statically positioned X-ray source;

a lower support unit;

at least one patient positioning device, said lower support unit supporting said at least one patient positioning device;

means for rotating said lower support unit about an about vertical axis to a plurality of rotation positions, wherein said plurality of rotation positions comprises at least five rotation positions in a period of less than two minutes during imaging of the tumor by the X-rays, said X-ray source configured to deliver the X-rays along an about horizontal axis over a portion of said lower support unit;

means for vertically adjusting said lower support unit, wherein said means for vertically adjusting adjusts the tumor of the patient to overlap protons extracted from a synchrotron, wherein during use the protons travel along a beam path substantially parallel to an X-ray path covered by said X-rays; and

independent control of all of;

a vertical position of said lower support unit, said lower support unit configured to support the patient during use;

a rotation position of said lower support unit;

energy of the protons, wherein said synchrotron comprises an extraction foil, in a proton beam acceleration path, used to control the energy of the protons; and

intensity of the protons, wherein an intensity controller uses electrons generated from said extraction foil in control of the intensity of the protons,

wherein delivery of the protons comprises coordination with rotation of the patient on said lower support unit during said plurality of rotation positions.

2. The apparatus of claim 1, further comprising motors configured to adjust at least one of a rotation position of said lower support unit and a vertical position of said lower support unit during delivery of the protons from said synchrotron.

3. The apparatus of claim 1, further comprising:

an upper support unit mechanically connected to said lower support unit, wherein said means for rotating rotates said lower support unit in synchronization with said upper support unit.

4. The apparatus of claim 3, further comprising:

a first thermal resistor held by said upper support unit, said first thermal resistor configured in an exhalation path of the patient;

a second thermal resistor configured to sense environmental temperature out of the exhalation path; and

a controller using at least one reading from said first thermal resistor and said second thermal resistor to determine a respiration cycle of the patient,

wherein said controller controls delivery of the X-rays from said X-ray source in phase with said respiration cycle.

5. The apparatus of claim 3, further comprising:

a motor for adjusting a distance between said lower support unit and said upper support unit.

6. The apparatus of claim 1, wherein said control of intensity comprises control through use of a feedback control using a current generated by the protons transmitting through said extraction foil in an extraction process of the protons at said energy.