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Non-invasive polarimetric apparatus and method for analyte sensing in birefringent media

  • US 8,718,734 B2
  • Filed: 11/07/2008
  • Issued: 05/06/2014
  • Est. Priority Date: 11/07/2007
  • Status: Active Grant
First Claim
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1. A noninvasive polarimetric apparatus used to measure levels of a substance in a sample, in which the sample may exhibit dynamically changing birefringence comprising:

  • a polarization system configured to generate multiple states of polarized light which interact with a given sample that exhibits dynamically changing birefringence, wherein the polarized light oscillates between left and right circularly polarized light, with elliptically polarized light between the left and right circularly polarized light; and

    ,an analyzer system configured to receive the resulting signal and generate a secondary signal which can be further processed to measure levels of a substance in the sample,wherein the measured levels provide a measurement of optical activity in relation to analyte concentration.

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