Apparatus and methods for detecting migration of neurostimulation leads

• US 8,718,757 B2
• Filed: 02/06/2012
• Issued: 05/06/2014
• Est. Priority Date: 04/01/2005
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Bradley, Kerry, Kapoor, Sunil K.
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): Dinga, Roland
• Application Number:
  US13/367,163
• Publication Number:
  US 20120136411A1
• Time in Patent Office: 820 Days
• Field of Search: 600/547, 600/554, 600/424, 607/2, 607/27, 607/28, 607/62, 607/116, 128/898, 128/899
• US Class Current: 607/2
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/3614 based on impedance measurement
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37241 providing test stimulations

Abstract

Apparatus and methods for detecting lead migration through the use of measured artifactual data about the tissue in the vicinity of the lead.

Claims

1. A neurostimulation system for use with an implantable neurostimulation lead, the neurostimulation system comprising:

at least one stimulation source; and

circuitry configured for taking a baseline evoked potential measurement by prompting the at least one stimulation source to convey a first stimulation pulse to tissue with the neurostimulation lead while at a baseline location, and measuring an evoked potential resulting from the conveyance of the first stimulation pulse to the tissue, configured for taking a subsequent evoked potential measurement by prompting the at least one stimulation source to convey a second stimulation pulse to tissue with the neurostimulation lead at a subsequent time after the neurostimulation lead has migrated from the baseline location, and measuring an evoked potential resulting from the conveyance of the second stimulation pulse to the tissue, and configured for determining a magnitude that the neurostimulation lead has migrated from the baseline position by comparing the subsequent evoked potential measurement to the baseline evoked potential measurement.

2. The neurostimulation system of claim 1, wherein the circuitry is configured for reprogramming a therapeutic regimen in response to a determination that the neurostimulation lead has migrated.

3. The neurostimulation system of claim 1, wherein the circuitry is configured for measuring the evoked potentials at the neurostimulation lead.

4. The neurostimulation system of claim 1, wherein the circuitry is configured for measuring the evoked potentials at another neurostimulation lead.

5. The neurostimulation system of claim 1, wherein the circuitry is further configured for maintaining the baseline evoked potential measurement as a non-trended baseline evoked potential measurement.

6. The neurostimulation system of claim 1, wherein the circuitry is further configured for creating a trended baseline evoked potential measurement based on the baseline evoked potential measurement.

7. The neurostimulation system of claim 6, wherein the trended baseline evoked potential measurement is a moving average that includes the baseline evoked potential measurement and the subsequent baseline evoked potential measurement.

8. The neurostimulation system of claim 6, wherein the trended baseline evoked potential measurement is based on a difference between the baseline evoked potential measurement and the subsequent evoked potential measurement.

9. The neurostimulation system of claim 8, wherein the circuitry is configured for creating the trended baseline evoked potential measurement by replacing the baseline evoked potential measurement with a new baseline evoked potential measurement if the difference is relatively small, and maintaining the baseline evoked potential measurement if the difference is relatively large.

10. The neurostimulation system of claim 9, wherein the new baseline evoked potential measurement is the subsequent baseline evoked potential measurement.

11. The neurostimulation system of claim 9, wherein the new baseline evoked potential measurement is an average of the baseline evoked potential measurement and the subsequent baseline evoked potential measurement.

12. The neurostimulation system of claim 1, wherein the circuitry is further configured for determining a direction in which the neurostimulation lead has migrated from the baseline location by comparing the subsequent evoked potential measurement to the baseline evoked potential measurement.

13. The neurostimulation system of claim 1, wherein the circuitry is configured for comparing the subsequent evoked potential measurement to the baseline evoked potential measurement using a feature comparison analysis.

14. The neurostimulation system of claim 1, wherein the control circuitry is configured for taking the baseline evoked potential measurement by conveying the first stimulation pulse to the tissue with a first electrode on the neurostimulation lead and measuring the resulting evoked potential at a second electrode, and configured for taking the subsequent evoked potential measurement by conveying the second stimulation pulse to the tissue with a third electrode on the neurostimulation lead and measuring the resulting evoked potential at a fourth electrode.

15. A neurostimulation system of claim 14, wherein the first, second, third, and fourth electrodes are on the neurostimulation lead.

16. A neurostimulation system of claim 14, wherein the circuitry is configured for determining the magnitude to which the neurostimulation lead has migrated to be the distance between the third electrode and the fourth electrode if the subsequent evoked potential measurement is similar to the baseline evoked potential measurement.

17. A neurostimulation system of claim 14, wherein the first and third electrodes are different electrodes.