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Swallowable drug delivery device and methods of drug delivery

  • US 8,721,620 B2
  • Filed: 12/23/2010
  • Issued: 05/13/2014
  • Est. Priority Date: 12/24/2009
  • Status: Active Grant
First Claim
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1. A method for delivering a therapeutic agent into the wall of a small intestine of a patient, the method comprising:

  • swallowing a drug delivery device comprising a release element and a solid therapeutic agent shaped as a tissue penetrating member configured to be inserted into the wall of a small intestine;

    wherein the solid therapeutic agent would chemically degrade if released within a lumen of the gastrointestinal tract;

    wherein the release element releases the solid therapeutic agent from the device into the wall of the small intestine responsive to a condition in the small intestine; and

    wherein the solid therapeutic agent penetrates into the wall of the small intestine such that the chemical degradation of the therapeutic agent in the lumen is inhibited.

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