Prosthetic valve for transluminal delivery

• US 8,721,708 B2
• Filed: 09/23/2011
• Issued: 05/13/2014
• Est. Priority Date: 11/17/1999
• Status: Expired due to Fees

• Current Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Original Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Inventors: Brtlein, Georg, Sguin, Jacques
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): SCHILLINGER, ANN M
• Application Number:
  US13/243,967
• Publication Number:
  US 20120083878A1
• Time in Patent Office: 963 Days
• Field of Search: 623 111- 154
• US Class Current: 623/1.24
• CPC Class Codes: A61B 17/0218 for minimally invasive surgery A61B17/0281, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/93 circumferentially expandable by using ratcheting locks
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections
• CPC Class Codes: A61F 2210/0023 operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 : conical
• CPC Class Codes: A61F 2230/0078 : hyperboloidal
• CPC Class Codes: A61F 2250/0003 : having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0039 : differing in diameter
• CPC Class Codes: A61F 2250/0048 : differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/0069 : Sealing means

Abstract

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchors may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. A radial restraint, comprising a wire, thread or cuff, may be used to ensure expansion does not exceed the preset diameter.

Claims

1. A prosthetic valve assembly, the valve assembly comprising:

a valve having a plurality of leaflets and commissure points; and

a valve support including a first zone and a second zone, the first zone being formed of a radially repeating shape of a first size and the second zone being formed of a radially repeating shape of a second size,

wherein the shape of the first size is smaller than the shape of the second size such that the radial expansion force in the first zone is greater than the radial expansion force in the second zone, and

wherein the valve longitudinally spans the first zone and the second zone.

2. The prosthetic valve assembly according to claim 1, wherein the radially repeating shape is a diamond-shaped mesh.

3. The prosthetic valve assembly according to claim 1, wherein the valve support is configured to be collapsible for transluminal delivery.

4. The prosthetic valve assembly according to claim 3, wherein the valve support is self-expanding.

5. The prosthetic valve assembly according to claim 1, wherein the second zone is an anchor configured to engage the vessel wall bordering an existing cardiac ring.

6. The prosthetic valve assembly according to claim 5, wherein the diameter of the second zone is greater than the diameter of the first zone.

7. The prosthetic valve assembly according to claim 1, wherein the commissure attachment holes are provided in the first zone proximal to the second zone.

8. A prosthetic valve assembly, the valve assembly comprising:

a valve having a plurality of leaflets and commissure points; and

a valve support including a first zone with a first radial expansion force and a second zone with a second radial expansion force less than the first radial expansion force;

wherein longitudinally spans the first zone and the second zone wherein the diameter of the second zone is configured to be larger than the diameter of the first zone.

9. The prosthetic valve assembly according to claim 8, wherein the valve support is configured to be collapsible for trans luminal delivery.

10. The prosthetic valve assembly according to claim 9, wherein the valve support is self-expanding.

11. The prosthetic valve assembly according to claim 8, wherein the valve support further comprises a valve support member including a valve support member thickness, the valve support member thickness being the difference between an inner radius and an outer radius of the valve support member;

wherein the valve support member thickness in the first zone is greater than the valve support member thickness in the second zone to provide a greater radial expansion force.

12. The prosthetic valve assembly according to claim 11, wherein the first zone of the valve support is configured to expand against leaflets of a deficient native valve;

and

wherein the valve support is configured to contact the leaflets of the deficient native valve at a first position in the first zone of the valve support.

13. The prosthetic valve assembly according to claim 12, wherein the radial expansion force of the valve support is greatest at the first position.