Intracardiac tracking system

• US 8,725,240 B2
• Filed: 08/20/2013
• Issued: 05/13/2014
• Est. Priority Date: 04/02/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Rhythmia Medical, Inc. (Boston Scientific Corporation)
• Inventors: Harlev, Doron, Badics, Zsolt, Eldar, Rotem
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Stice, Paula J
• Application Number:
  US13/970,742
• Publication Number:
  US 20130345538A1
• Time in Patent Office: 266 Days
• Field of Search: 600508-509, 600/424, 600/547, 606/34, 606/41
• US Class Current: 600/509
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2562/0214 Capacitive electrodes
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/061 Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body A61B1/00158 takes precedence
• CPC Class Codes: A61B 5/063 using impedance measurements
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 5/068 using impedance sensors
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence

Abstract

In general, in one aspect, a method is disclosed for determining information about a position of an object. The method includes: (i) causing current to flow between each of three or more sets of current-injecting electrodes on a first catheter inserted into an organ in a patient'"'"'s body, the organ having a periphery (ii) in response to current flow caused by each set of current injecting electrodes, measuring an electrical signal at each of one or more measuring electrodes located on one or more additional catheters inserted into the organ in the patient'"'"'s body and (iii) determining the position of each of one or more of the measuring electrodes on the additional catheters relative to the first catheter based on the measured signals from the one or more measuring electrodes.

Claims

1. A method comprising:

causing current to flow between each of three or more sets of current-injecting electrodes on a first catheter inserted into an organ in a patient'"'"'s body, the organ having a periphery;

in response to current flow caused by each set of current injecting electrodes, measuring electric signals at each of multiple measuring electrodes on the first catheter and measuring an electrical signal at each of one or more measuring electrodes located on one or more additional catheters inserted into the organ in the patient'"'"'s body; and

determining the position of each of one or more of the measuring electrodes on the one or more additional catheters relative to the first catheter based on the measured signals for the measuring electrodes on the first catheter and the one or more additional catheters, the determination associating each measured signal with a homogeneous component that depends on the relative position of each signal measuring electrode with respect to each set of current injecting electrodes and an inhomogeneous component associated with the periphery of the organ.

2. The method of claim 1, wherein the inhomogeneous component is modeled as a variation in electric potential along a surface enclosing at least the first catheter that depends on the relative positions between the current injecting electrodes and the signal measuring electrodes and on an estimate for conductivity inside the organ.

3. The method of claim 1, wherein the determination accounts for a change in conductivity at the organ'"'"'s periphery.

4. The method of claim 1, wherein the determination associates each measured signal with a homogeneous component and an inhomogeneous component associated with the organ'"'"'s periphery.

5. The method of claim 1, wherein the determination comprises an optimization technique that minimizes collective differences between each of the measured signals and an estimate for each of the respective measured signals as a function of the relative position between each of the measuring electrodes on the first and the one or more additional catheters and the sets of current-injecting electrodes on the first catheter and the change in conductivity at the organ'"'"'s periphery.

6. The method of claim 1, wherein the determination comprises an optimization technique that minimizes collective differences between each of the measured signals and an estimate for each of the respective measured signals as a function of the relative position between each of the measuring electrodes on the first and the one or more additional catheters and the sets of current-injecting electrodes on the first catheter and the estimate for conductivity inside the organ.

7. The method of claim 1, wherein the determination comprises an optimization technique that minimizes collective differences between each of the measured signals and an estimate for each of the respective measured signals as a function of the relative position between each of the measuring electrodes on the first and the one or more additional catheters and the sets of current-injecting electrodes on the first catheter, the change in conductivity at the organ'"'"'s periphery and the estimate for conductivity inside the organ.

8. The method of claim 1, further comprising using the multiple signal measuring electrodes on the first catheter to measure cardiac signals.

9. The method of claim 1, further comprising securing at least three electrodes to be used for reference to fixed locations within the organ.

10. The method of claim 9, further comprising determining a position of each of the reference electrodes relative to the first catheter and determining a location of each of the one or more electrodes on the one or more additional catheters relative to the surface of the organ.

11. The method of claim 10, wherein determining a location of each of the one or more electrodes on the one or more additional catheters relative to the surface of the organ comprises correcting a location of the one or more additional catheters based on a movement of the organ.

12. The method of claim 10, wherein determining a location of each of the one or more electrodes on the second catheter relative to the surface of the organ comprises correcting a location of each of the one or more electrodes on the second catheter based on a movement of the first catheter.

13. The method of claim 10, further comprising determining the position of each of the one or more the measuring electrodes on the second catheter relative to the surface of the organ by solving an optimization problem that minimizes collective difference between a reference distribution of the reference electrodes based on the fixed locations and a determined position of each of the reference electrodes.

14. The method of claim 1, further comprising using multiple signal measuring electrodes on the first catheter and the one or more electrodes on the one or more additional catheters to measure cardiac signals.

15. The method of claim 14, further comprising moving a catheter comprising an ablation electrode inside the organ and tracking the position of the ablation electrode on that catheter relative to the surface of the organ based on signals measured by the ablation electrode in response to current flow caused by each set of current injecting electrodes on the first catheter.

16. The method of claim 1, wherein measuring the electrical signal at each of the one or more measuring electrodes on the one or more additional catheters comprises simultaneously measuring the electrical signal at each the one or more measuring electrodes on the one or more additional catheters.

17. The method of claim 1, wherein the determination comprises an optimization technique that minimizes collective differences between each of the measured signals and an estimate for each of the respective measured signals as a function of the relative position between each of the one or more measuring electrodes on the one or more additional catheters and the sets of current-injecting electrodes on the first catheter.

18. The method of claim 1, wherein determining the position of each of the one or more measuring electrodes on the second catheter relative to the first catheter based on the measured signals from the one or more electrodes comprises distinguishing cardiac signals from signals responsive to the injected current.

19. The method of claim 1, further comprising displaying the position of the one or more additional catheters relative to a surface of the organ.