Interventional catheter for retrograde use having embolic protection capability and methods of use

• US 8,728,113 B2
• Filed: 08/13/2012
• Issued: 05/20/2014
• Est. Priority Date: 12/21/2005
• Status: Active Grant

• Current Assignee: Mark C. Bates
• Original Assignee: Nexeon MedSystems, Inc.
• Inventors: Bates, Mark C.
• Primary Examiner(s): SEVERSON, RYAN J
• Application Number:
  US13/584,517
• Publication Number:
  US 20120310272A1
• Time in Patent Office: 645 Days
• Field of Search: 600/562, 604104-106, 606/110, 606/113, 606/114, 606/127, 606/128, 606/200
• US Class Current: 606/200
• CPC Class Codes: A61F 2/014 Retrograde blood flow filters, i.e. device inserted against the blood flow direction
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0097 Harpoon-shaped
• CPC Class Codes: A61F 2250/0039 differing in diameter

Abstract

Interventional catheters are disclosed for use in performing diagnostic and therapeutic procedures in vessels that are accessed retrograde to blood flow. The catheters include an elongated shaft slidably disposed within a sheath, a distal region having an end effector and a filter disposed proximal to the end effector to capture emboli liberated during the diagnostic or therapeutic procedure. The filter includes a plurality of struts that cooperate with an exterior surface of the catheter to define a reservoir to retain captured emboli, the reservoir configured so that advancement of the sheath contracts the filter without squeezing or dislodging captured emboli beyond a distal end of the filter.

Claims

1. An interventional catheter for use in a vessel, comprising:

an inner member having an exterior surface and a reduced diameter region;

a filter disposed on the inner member at the reduced diameter region, the filter comprising a plurality of longitudinally extending struts and an annular distal circumferential ring; and

a sheath slidably disposed on the inner member, the sheath movable from an extended position, wherein a distal end of the sheath retains the filter in a collapsed configuration, to a retracted position, wherein the filter is in a deployed configuration and the distal end of the sheath is located proximal to the filter, and

wherein the filter is configured so that the annular distal circumferential ring contacts the exterior surface of the inner member before the longitudinally extending struts.

2. The catheter of claim 1, wherein the plurality of longitudinally extending struts support a filter mesh.

3. The catheter of claim 2, wherein the filter mesh has a multiplicity of pores, the size of the pores sufficient to permit blood to pass through the filter, but to capture embolic material.

4. The catheter of claim 1, wherein each one of the plurality of longitudinally extending struts has a length longer than the reduced diameter region.

5. The catheter of claim 1, wherein the plurality of longitudinally extending struts are configured to seal the reduced diameter region in the extended position to define a reservoir and to retain emboli captured by the filter.

6. The catheter of claim 1, wherein the plurality of longitudinally extending struts are configured to self-expand to the deployed configuration upon retraction of the sheath.

7. The catheter of claim 1, wherein the inner member further comprises a diagnostic or therapeutic end effector located distal to the filter.

8. The catheter of claim 7, wherein the end effector comprises a balloon.

9. The catheter of claim 8, further comprising a stent disposed on the balloon.

10. The catheter of claim 1, wherein the sheath is configured such that a diagnostic or therapeutic procedure may be performed therethrough.

11. The catheter of claim 1, wherein the sheath is movable from the retracted position to the extended position.

12. The catheter of claim 1, wherein the plurality of longitudinally extending struts comprise four or more struts.

13. The catheter of claim 1, further comprising one or more radiopaque markers affixed to the inner member.

14. The catheter of claim 1, further comprising one or more radiopaque markers affixed to the plurality of longitudinally extending struts.

15. The catheter of claim 1, wherein the filter comprises a mounting ring.

16. The catheter of claim 15, wherein the mounting ring comprises a superelastic alloy.

17. The catheter of claim 1, wherein the plurality of longitudinally extending struts are integrally formed with a mounting ring that couples the plurality of longitudinally extending struts to the inner member.

18. The catheter of claim 17, wherein the plurality of longitudinally extending struts and the mounting ring comprise a superelastic alloy.

19. The catheter of claim 1, wherein a portion of the inner member has a diameter of 5 French.

20. The catheter of claim 1, wherein the inner member further comprises a guide wire lumen extending through a distal end of the inner member.