Flow disrupting devices

• US 8,728,117 B1
• Filed: 12/02/2013
• Issued: 05/20/2014
• Est. Priority Date: 07/29/2013
• Status: Active Grant

• Current Assignee: Insera Therapeutics, Inc.
• Original Assignee: Insera Therapeutics, Inc.
• Inventors: Janardhan, Vallabh, Janardhan, Vikram
• Primary Examiner(s): MILES, JONATHAN WADE
• Application Number:
  US14/093,831
• Time in Patent Office: 169 Days
• Field of Search: 623/1.13, 623/1.14, 623/1.15, 623/1.16, 623/1.17, 623/1.18, 623/1.19, 623/1.2, 623/1.21, 623/1.3, 623/1.31, 623/1.34, 623/1.51, 623/1.53, 623/13.19, 606/159, 606/191, 606/194, 606/198, 606/200, 606/213, 606/214, 606/215, 606/216, 606/228, 606/229, 606/230, 606/231, 600/139, 600/140, 600/141, 600/142, 600/146, 600/587, 604/523, 604/524, 604/525, 128/831, 128/843
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/22032 having inflatable gripping elements balloon catheters A61M25/10
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/32056 Surgical snare instruments for removing or smashing calculi A61B2017/2212; tonsillotomes A61B17/26
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00641 for closing fistulae, e.g. anorectal fistulae
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/22001 Angioplasty, e.g. PCTA
• CPC Class Codes: A61B 2017/22002 preventing restenosis
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22035 for retrieving or repositioning foreign objects
• CPC Class Codes: A61B 2017/22067 : Blocking; Occlusion A61B2017/22054 takes precedence
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 90/39 : Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/011 : Instruments for their placement or removal
• CPC Class Codes: A61F 2002/018 : made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61M 1/74 : Suction control underwater drainage A61M1/61
• CPC Class Codes: A61M 1/84 : Drainage tubes; Aspiration tips for negative pressure wound therapy A61M1/90; for surgical cutting instruments A61B17/32
• CPC Class Codes: A61M 2025/0042 : Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2202/06 : Solids
• CPC Class Codes: A61M 2207/10 : Device therefor
• CPC Class Codes: A61M 2210/12 : Blood circulatory system
• CPC Class Codes: A61M 25/0023 : by the form of the lumen, e.g. cross-section, variable diameter
• CPC Class Codes: A61M 25/10 : Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 29/00 : Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00
• CPC Class Codes: B23K 26/083 : Devices involving movement of the workpiece in at least one axial direction
• CPC Class Codes: B23K 26/14 : using a fluid stream, e.g. a jet of gas, in conjunction with the laser beam; Nozzles therefor B23K26/12 takes precedence
• CPC Class Codes: B23K 26/142 : for the removal of by-products
• CPC Class Codes: B23K 26/1435 : involving specially adapted flow control means
• CPC Class Codes: B23K 26/146 : the fluid stream containing a liquid
• CPC Class Codes: B23K 26/20 : Bonding soldering by means of radiant energy B23K1/005; joining of preformed plastics parts by heating using laser beam B29C65/16
• CPC Class Codes: B23K 26/38 : by boring or cutting
• CPC Class Codes: B26F 3/004 : by means of a fluid jet methods for use of abrasive blasting for cutting B24C1/045; guns for abrasive fluid jets B24C5/02; perforating by non-mechanical means, e.g. by fluid jet B26F1/26
• CPC Class Codes: D04C 1/06 : Braid or lace serving particular purposes
• CPC Class Codes: D04C 1/12 : Cords, lines, or tows
• CPC Class Codes: D04C 3/48 : Auxiliary devices
• CPC Class Codes: D10B 2403/0333 : with tubular portions of variable diameter or distinct axial orientation
• CPC Class Codes: D10B 2509/06 : Vascular grafts; stents
• CPC Class Codes: Y10T 137/8376 : Combined
• CPC Class Codes: Y10T 137/85954 : Closed circulating system
• CPC Class Codes: Y10T 156/10 : Methods of surface bonding and/or assembly therefor
• CPC Class Codes: Y10T 29/49913 : by constricting outer annulus
• CPC Class Codes: Y10T 29/49995 : Shaping one-piece blank by removing material
• CPC Class Codes: Y10T 82/2521 : Bar feeder

Abstract

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Claims

1. A device for treating a vascular cavity, the device comprising:

a plurality of wires woven to form a textile structure expandable between a radially compressed state and a radially expanded state, the textile structure in the radially expanded state comprising;

a first bulb, the first bulb having a first braid angle, the first bulb having a first diameter, the first bulb having a porosity configured to decrease flow into and out of the vascular cavity,

a second bulb, the second bulb having a second braid angle less than the first braid angle, the second bulb having a second diameter,

a third bulb, the second bulb between the first bulb and the third bulb, the third bulb having a third braid angle less than the first braid angle, the third bulb having a third diameter less than the first diameter,

a first neck between the first bulb and the second bulb, the first neck having a fourth braid angle less than the first braid angle, the first neck having a fourth diameter less than the first diameter and the second diameter,

a second neck between the second bulb and the third bulb, the second neck having a fifth braid angle less than the first braid angle, the second neck having a fifth diameter less than the second diameter and the third diameter,

a third neck extending from the third bulb, and

a fourth neck extending from the first bulb.

2. The device of claim 1, wherein the textile structure in the radially expanded state further comprises:

a fourth bulb between the first bulb and the first neck, the fourth bulb having a sixth braid angle greater than the second braid angle, the third braid angle, the fourth braid angle, and the fifth braid angle, the fourth bulb having a sixth diameter, and

a fourth neck between the first bulb and the fourth bulb, the fourth neck having a seventh diameter less than the first diameter and the sixth diameter.

3. The device of claim 2, wherein the sixth diameter is less than the first diameter and greater than the third diameter.

4. The device of claim 2, wherein the fourth bulb has a porosity configured to decrease flow into the vascular cavity.

5. The device of claim 1, wherein each of the first bulb, the second bulb, and the third bulb has a shape of an ellipsoid or oblate spheroid having a polar axis diameter smaller than an equatorial axis diameter.

6. The device of claim 5, wherein the first bulb, the second bulb, and the third bulb are coupled along the polar axes of the first bulb, the second bulb, and the third bulb.

7. The device of claim 1, wherein the textile structure is mechanically or electrolytically detachable from a proximal portion at a joint.

8. The device of claim 1, wherein the first braid angle is between 91°

and 180°

.

9. The device of claim 1, further comprising a proximal portion detachably coupled to the textile structure, wherein each of the first bulb, the second bulb, and the third bulb has a shape of an ellipsoid or oblate spheroid having a polar axis diameter smaller than an equatorial axis diameter, wherein the first bulb, the second bulb, and the third bulb are coupled along the polar axes of the first bulb, the second bulb, and the third bulb, and wherein the textile structure in the radially expanded state further comprises:

a fourth bulb between the first bulb and the first neck, the fourth bulb having a sixth braid angle greater than the second braid angle, the third braid angle, the fourth braid angle, and the fifth braid angle, the fourth bulb having a sixth diameter less than the first diameter and greater than the third diameter, wherein the fourth bulb has a porosity configured to decrease flow into the vascular cavity, and

a fourth neck between the first bulb and the fourth bulb, the fourth neck having a seventh diameter less than the first diameter and the sixth diameter.

10. A device for treating a vascular cavity, the device comprising:

a textile structure changeable between a radially compressed state and a radially expanded state,

the textile structure comprising, in the radially expanded state, a plurality of bulbs along a longitudinal axis from a proximal end to a distal end, wherein the plurality of bulbs comprises a proximal-most bulb having a first braid angle, at least one bulb distal to the proximal-most bulb having a second braid angle less than the first braid angle,

each said bulb longitudinally spaced from another said bulb by a neck, at least one neck distal to the proximal-most bulb having a third braid angle less than the first braid angle,

the proximal-most bulb of the plurality of bulbs having a porosity configured to reduce flow into the vascular cavity; and

a proximal portion coupled to the textile structure at a joint proximal to the proximal-most bulb,

the textile structure detachable from the proximal portion at the joint.

11. The device of claim 10, wherein the plurality of bulbs comprises:

a second bulb distal to the proximal-most bulb, the second bulb having the second braid angle; and

a third bulb distal to the second bulb, the third bulb having a fourth braid angle less than the first braid angle.

12. The device of claim 10, wherein the plurality of bulbs comprises:

a second bulb distal to the proximal-most bulb, the second bulb having a fourth braid angle;

a third bulb distal to the second bulb, the third bulb having the second braid angle less than the first braid angle and the fourth braid angle; and

a fourth bulb distal to the third bulb, the fourth bulb having a fifth braid angle less than the first braid angle and the fourth braid angle.

13. The device of claim 10, wherein each of the plurality of bulbs has a shape of an ellipsoid or oblate spheroid having a polar axis diameter smaller than an equatorial axis diameter.

14. The device of claim 13, wherein the plurality of bulbs are coupled along the polar axes.

15. The device of claim 10, wherein the textile structure is mechanically detachable from the proximal portion at the joint.

16. The device of claim 10, wherein the textile structure is electrolytically detachable from the proximal portion at the joint.

17. The device of claim 10, wherein the plurality of bulbs comprises:

a second bulb distal to the proximal-most bulb, the second bulb having the second braid angle;

a third bulb distal to the second bulb, the third bulb having the second braid angle; and

a distal neck distal to a distal-most bulb of the plurality of bulbs, the distal neck having a free distal end,

wherein each of the plurality of bulbs has a shape of an ellipsoid or oblate spheroid having a polar axis diameter smaller than an equatorial axis diameter,

wherein the plurality of bulbs are coupled along the polar axes,

wherein the first braid angle is between 91° and

180°

, and

wherein the textile structure is completely hollow.

18. A device for treating a vascular cavity, the device comprising:

a structure transformable between a radially compressed state and a radially expanded state,

the structure comprising, in the radially expanded state, a plurality of bulbs, wherein the plurality of bulbs comprises a proximal-most bulb having a first braid angle, at least one bulb distal to the proximal-most bulb having a second braid angle less than the first braid angle,

each said bulb longitudinally spaced from another said bulb by a neck, at least one neck distal to the proximal-most bulb having a third braid angle less than the first braid angle,

the proximal-most bulb having a porosity configured to inhibit flow into the vascular cavity.

19. The device of claim 18, wherein the structure comprises a plurality of wires, and wherein the plurality of bulbs comprises:

a second bulb distal to the proximal-most bulb, the second bulb having the second braid angle; and

a third bulb distal to the second bulb, the third bulb having the second braid angle,

wherein the first braid angle is between about 91° and

about 180°

, and

wherein the textile structure is completely hollow.

20. The device of claim 18, wherein each of the plurality of bulbs has a shape of an ellipsoid or oblate spheroid having a polar axis diameter smaller than an equatorial axis diameter and wherein the plurality of bulbs are coupled along the polar axes.