Compositions and methods for therapeutic delivery with frozen particles
First Claim
Patent Images
1. A system comprising:
- at least one computing device;
at least one computer program, configured with a computer-readable medium, for use with at least one computer system and wherein the computer program includes a plurality of instructions that when executed on the computing device cause the computing device to direct a pre-determined patterned delivery of a plurality of frozen particle therapeutic compositions to at least one biological tissue of at least one subject by a remote controlled device, the plurality of frozen particle therapeutic compositions including at least two sub-sets of frozen particles that include different therapeutic agents and at least one tracer agent; and
compare information related to the delivery with information regarding at least one clinical outcome following receipt by the at least one subject; and
at least one imaging device configured to measure the at least one tracer agent and provide real-time feedback control of the plurality of frozen particle therapeutic compositions administered to the at least one subject.
3 Assignments
0 Petitions
Accused Products
Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
292 Citations
30 Claims
-
1. A system comprising:
-
at least one computing device; at least one computer program, configured with a computer-readable medium, for use with at least one computer system and wherein the computer program includes a plurality of instructions that when executed on the computing device cause the computing device to direct a pre-determined patterned delivery of a plurality of frozen particle therapeutic compositions to at least one biological tissue of at least one subject by a remote controlled device, the plurality of frozen particle therapeutic compositions including at least two sub-sets of frozen particles that include different therapeutic agents and at least one tracer agent; and
compare information related to the delivery with information regarding at least one clinical outcome following receipt by the at least one subject; andat least one imaging device configured to measure the at least one tracer agent and provide real-time feedback control of the plurality of frozen particle therapeutic compositions administered to the at least one subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 30)
-
-
23. A system, comprising:
-
at least one computing device; at least one computer program, configured with a computer-readable medium, for use with at least one computer system and wherein the computer program includes a plurality of instructions that when executed on the computing device cause the computing device to direct a pre-determined patterned delivery of a plurality of frozen particle therapeutic compositions to at least one biological tissue of at least one subject by a remote controlled device, the plurality of frozen particle therapeutic compositions including at least two sub-sets of frozen particles that include different therapeutic agents and at least one tracer agent, and compare information related to the delivery, and information regarding the plurality of frozen particle therapeutic compositions; one or more instructions for applying one or more comparisons to the information related to the delivery to a plurality of people; detect the at least one tracer agent, and provide real-time feedback control of the amount of the plurality of frozen particle therapeutic compositions administered to the at least one subject. - View Dependent Claims (24, 25, 26, 27, 28)
-
-
29. A system, comprising:
-
at least one computing device; at least one computer program, configured with a computer-readable medium, for use with at least one computer system and wherein the computer program includes a plurality of instructions that when executed on the at least one computing device cause the computing device to direct a pre-determined patterned delivery of a plurality of frozen particle therapeutic compositions to at least one biological tissue of at least one subject by a remote controlled device, the plurality of frozen particle therapeutic compositions including at least two sub-sets of frozen particles that include different therapeutic agents and at least one tracer agent; and
compare information relating to delivery, and information regarding at least one frozen particle therapeutic composition of the plurality;one or more instructions for applying one or more comparisons to the information related to delivery to a plurality of people; one or more instructions for determining from the comparison at least one biological change following administration of one or more frozen particle therapeutic compositions of the plurality to the subject; and at least one imaging device configured to measure the at least one tracer agent and provide real-time feedback control of the amount of the at least one frozen particle therapeutic composition administered to the at least one subject.
-
Specification